Patents by Inventor Marie P. Foloppe

Marie P. Foloppe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5332735
    Abstract: Compounds of the general formula (I): ##STR1## where A, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are defined in the description.Medicinal products.
    Type: Grant
    Filed: November 14, 1991
    Date of Patent: July 26, 1994
    Assignee: Adir et Compagnie
    Inventors: Sylvain Rault, Marie P. Foloppe, Max Robba, Michel Boulouard, Pierre Renard, Michelle Devissaguet, Gerard Adam
  • Patent number: 5153190
    Abstract: The invention relates to pyrrolo [1,2-a] thieno [3,2-f][1,4]diazepine compounds of the formula (I) ##STR1## in which: R.sub.1 is hydrogen; alkyl optionally substituted with alkoxy, hydroxy, cycloalkyl, or phenyl; or alkyl- or arylsulfonyl; R.sub.2 is hydrogen, phenyl, or phenylalkyl; alkyl optionally substituted with hydroxyl, alkoxy, oxo, cycloalkyl or phenyl; or optionally substituted amino; R.sub.3 represents hydrogen or alkyl, and R.sub.4 and R.sub.5 independently represent: hydrogen, alkyl optionally substituted with alkoxy, cycloalkyl, or phenyl; or phenyl; their isomers, diastereoisomers and enantiomers as well as their addition salts with pharmaceutically-acceptable acids. The compounds are useful for treating cerebral ischemia, hypertriglyceridemia, hypercholesterolemia, hyperlipidemia, and hyperglycemia and are obtained in a few steps from the corresponding substituted 2-(1-pyrrolyl)thiophenes ##STR2## Y=--CHO or H; X= CN, CONH.sub.2, CH.sub.2 NHCOR.sub.2, or CH.sub.2 NH.sub.2.
    Type: Grant
    Filed: March 7, 1991
    Date of Patent: October 6, 1992
    Assignee: Adir et Compagnie
    Inventors: Sylvain Rault, Michel Boulouard, Marie P. Foloppe, Max Robba, Beatrice Guardiola, Michelle Devissague