Abstract: A simulation system stores information representing a plurality of scenarios of index vectors generated by simulation and a plurality of clusters in which the index vectors in each of a plurality of time steps are classified, classifies the clusters of a final time step of the plurality of scenarios into a plurality of groups, calculates a transition probability at which the index vectors belonging to the cluster in the time step transition to each group in the final time step for each of combinations of the time steps and the clusters and a cluster in which the index vectors belonging to the cluster in the time step are transmissible in a subsequent step, and displays the transition probability and the transmissible cluster.

Abstract: Provided is an innovative method for sterilization or inactivation treatment of heat-resistant spore-forming bacteria that demonstrates a sufficient sterilization effect in a reliable manner and that can be implemented using simple equipment by reducing the heat resistance of heat-resistant spore-forming bacteria by the effect of decompression treatment in a high-pressure process, and by carrying out a heat sterilization treatment after a predetermined resting time has elapsed after the decompression to thereby sterilize and inactivate heat-resistant bacteria that have reduced heat resistance. A method for sterilizing or inactivating heat-resistant spore-forming bacteria by performing, as a pretreatment of a heat sterilization treatment, a high-pressure treatment in which a hydrostatic pressure of 50 MPa or more and 200 MPa or less is applied to an object under a temperature of 50° C.