Patents by Inventor Marinus Petrus MACHIELSEN

Marinus Petrus MACHIELSEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetically modified (R)-lactic acid producing thermophilic bacteria
    Patent number: 10731186
    Abstract: The invention relates to a genetically engineered thermophilic bacterial cell that is facultative anaerobic comprising: a) inactivation or deletion of the endogenous (S)-lactate dehydrogenase gene; b) introduction of a (R)-lactate dehydrogenase gene; c) inactivation or deletion of the endogenous pyruvate formate lyase A and/or B gene.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: August 4, 2020
    Assignee: PURAC BIOCHEM BV
    Inventors: Marinus Petrus Machielsen, Mariska Van Hartskamp, Richard Van Kranenburg
  • Genetic modification of (S)-lactic acid producing thermophilic bacteria
    Patent number: 10273509
    Abstract: A genetically engineered thermophilic bacterial cell that is facultative anaerobic and (S)-lactic acid producing including inactivation or deletion of the endogenous methylglyoxal synthase gene mgsA.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: April 30, 2019
    Assignee: PURAC BIOCHEM B.V.
    Inventors: Richard Van Kranenburg, Anna Verhoef, Marinus Petrus Machielsen
  • GENETIC MODIFICATION OF (S)-LACTIC ACID PRODUCING THERMOPHILIC BACTERIA
    Publication number: 20170298398
    Abstract: A genetically engineered thermophilic bacterial cell that is facultative anaerobic and (S)-lactic producing including inactivation or deletion of the endogenous methylglyoxal synthase gene mgsA.
    Type: Application
    Filed: July 13, 2015
    Publication date: October 19, 2017
    Applicant: PURAC BIOCHEM B.V.
    Inventors: Richard VAN KRANENBURG, Anna VERHOEF, Marinus Petrus MACHIELSEN
  • GENETICALLY MODIFIED (R)-LACTIC ACID PRODUCING THERMOPHILIC BACTERIA
    Publication number: 20170275656
    Abstract: The invention relates to a genetically engineered thermophilic bacterial cell that is facultative anaerobic comprising: a) inactivation or deletion of the endogenous (S)-lactate dehydrogenase gene; b) introduction of a (R)-lactate dehydrogenase gene; c) inactivation or deletion of the endogenous pyruvate formate lyase A and/or B gene.
    Type: Application
    Filed: July 13, 2015
    Publication date: September 28, 2017
    Applicant: PURAC BIOCHEM BV
    Inventors: Marinus Petrus MACHIELSEN, Mariska VAN HARTSKAMP, Richard VAN KRANENBURG