Abstract: An order picking system includes a robot and pallet support shuttle which i) loads an empty pallet from an empty pallet distribution system, ii) carries the empty pallets adjacent a selected one of a plurality of SKU pallet stations including selected products; iii) charges one or a plurality of the selected products from the selected one of the SKU pallet stations on the one of the empty pallets, iv) repeats steps ii) and iii) until a mixed pallet is completed according to an order; and iv) unloads the mixed pallet onto a mixed pallet receiver to be picked up. The shuttle includes a robot and a pallet-receiving area both moving in unison on a rail. This minimizes robot traveling since the mixed pallet always travels with the robot. The order picking system is enclosed with safety fencing having limited pick and drop areas.