Patents by Inventor Mario Fantucci

Mario Fantucci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6211380
    Abstract: A process for the preparation of heteroaryl-zinc halides of the formula (II): Het—Zn—X, wherein Het is an optionally substituted 5 or 6 membered aromatic heterocyclic group with one or two heteroatoms selected among nitrogen, oxygen or sulphur; X is a chlorine, bromine or iodine atom; comprising metallation reaction of heteroarylhalide with metallic zinc optionally activated by washing with acids, is described. Compounds of the formula (II) are intermediates useful in the synthesis for the preparation of compounds endowed with pharmacological activity.
    Type: Grant
    Filed: July 8, 1999
    Date of Patent: April 3, 2001
    Assignee: Zambon Group S.p.A.
    Inventors: Mario Fantucci, Francesco Santangelo
  • Patent number: 6177571
    Abstract: A method for removing heavy metals, selected from palladium, tin and nickel, from heavy metal complexes with thiazole compounds in aqueous or alcoholic solution, by precipitation as sulfides, characterised in that such solutions are treated with a water-soluble ammonium, alkaline or alkaline-earth sulfide.
    Type: Grant
    Filed: September 27, 1999
    Date of Patent: January 23, 2001
    Assignee: Zambon Group S.p.A.
    Inventor: Mario Fantucci
  • Patent number: 5994539
    Abstract: Compounds of formula ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, m and n have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as active ingredients are described.The compounds of formula I are endowed with a mixed ACE-inhibitory and NEP-inhibitory activity and are useful in the treatment of cardiovascular diseases.
    Type: Grant
    Filed: December 18, 1997
    Date of Patent: November 30, 1999
    Assignee: Zambon Group S.p.A.
    Inventors: Franco Pellacini, Stefano Romagnano, Gabriele Norcini, Francesco Santangelo, Mario Fantucci, Claudio Semeraro
  • Patent number: 5760241
    Abstract: Compounds of formula ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, m and n have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as active ingredients are described.The compounds of formula I are endowed with a mixed ACE-inhibitory and NEP-inhibitory activity and are useful in the treatment of cardiovascular diseases.
    Type: Grant
    Filed: December 24, 1996
    Date of Patent: June 2, 1998
    Assignee: Zambon Group S.p.A.
    Inventors: Francesco Santangelo, Mario Fantucci, Claudio Semeraro, Franco Pellacini, Stefano Romagnano, Gabriele Norcini
  • Patent number: 5556829
    Abstract: Compounds of formula ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and X have the meanings reported in the description, can be used in compositions for agricultural use in particular as herbicides in the defense of useful crops from weeds.
    Type: Grant
    Filed: May 27, 1994
    Date of Patent: September 17, 1996
    Assignees: Zambon Group S.p.A., Agrimont S.p.A.
    Inventors: Giovanni Camaggi, Dario Chiarino, Mario Fantucci, Giovanni Meazza
  • Patent number: 5336664
    Abstract: Compounds of formula ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and X have the meanings reported in the description, can be used in compositions for agricultural use in particular as herbicides in the defence of useful crops from weeds.
    Type: Grant
    Filed: April 22, 1991
    Date of Patent: August 9, 1994
    Assignees: Zambon Group S.p.A., Agrimont S.r.l.
    Inventors: Giovanni Camaggi, Dario Chiarino, Mario Fantucci, Giovanni Meazza
  • Patent number: 4988691
    Abstract: Compounds of formula ##STR1## (wherein R, R.sub.1, R.sub.2 and Y have the meanings indicated in the description), a process for the preparation thereof and pharmaceutical compositions containing them as active ingredient are described.Compounds of formula I exhibit anto-serotonin activity.
    Type: Grant
    Filed: January 8, 1990
    Date of Patent: January 29, 1991
    Assignee: Zambon Group S.p.A.
    Inventors: Giancarlo Benelli, Angelo Carenzi, Dario Chiarino, Mario Fantucci
  • Patent number: 4918095
    Abstract: The compound N-[(1S,2R)-fluoromethyl-2-hydroxy-2-(4-methylsulphonyl-phenyl)-ethyl]-2-pr openamide and the derivatives thereof in which the hydroxy in 2 position is esterified by a mono or dicarboxylic acid or by an aminoacid are described.Such compounds have antibiotic activity and are useful in human and veterinary therapy.
    Type: Grant
    Filed: December 18, 1987
    Date of Patent: April 17, 1990
    Assignee: Zambon S.p.A.
    Inventors: Davide Della Bella, Giancarlo Jommi, Mario Fantucci, Dario Chiarino
  • Patent number: 4638003
    Abstract: N-substituted derivatives of 1-(4'-alkylthiophenyl)-2-amino-1,3-propanediol, their salts with pharmaceutically acceptable organic and inorganic acids, processes for preparing them, pharmaceutical compositions containing them and intermediates useful in the preparation thereof.The novel derivatives according to this invention are endowed with calcium antagonist activity and are useful as antiarrhythmic and vasodilating agents.
    Type: Grant
    Filed: August 1, 1984
    Date of Patent: January 20, 1987
    Assignee: Zambon S.p.A.
    Inventors: Dario Chiarino, Angelo Carenzi, Davide Della Bella, Mario Fantucci
  • Patent number: 4632940
    Abstract: N-substituted derivatives of 1-(4'-alkylsulfonylphenyl)-2-amino-1,3-propanediol, their salts with pharmaceutically acceptable organic and inorganic acids, processes for preparing them, pharmaceutical compositions containing them and intermediates useful in the preparation thereof.The novel derivatives according to this invention are endowed with local anesthetic activity.
    Type: Grant
    Filed: August 3, 1984
    Date of Patent: December 30, 1986
    Assignee: Zambon S.p.A.
    Inventors: Dario Chiarino, Angelo Carenzi, Davide Della Bella, Mario Fantucci