Abstract: The invention concerns an injector device (100), comprising access means (110, 115) configured to selectively allow and prevent a cartridge (120) storing a pharmaceutical product (122) from being removed from the injector device (100), a self-test unit (130) configured to cause a self-test of at least one of an electronic component and an electronic assembly of the injector device (100), and a control unit (140) configured to control the access means (110, 115) to allow the cartridge (120) to be removed from the injector device (100) in case the self-test has failed.

Abstract: The present disclosure relates to a system (100) for use of a pharmaceutical product. The system comprises a container (102) accommodating a pharmaceutical product, the container (102) comprising a wireless communication unit (112) and a memory (116) which stores pairing-specific information for one or more medical devices (104), and a medical device (104) enabled for wireless communication with the wireless communication unit (112) of the container (102) and configured to read the pairing-specific information from the memory (116) of the container (102) to verify whether the container (102) is permitted to be used by the medical device (104).

Abstract: A prosthetic heart valve includes a support frame and a plurality of leaflets disposed inside the support frame. The support frame extends between an inflow end and an outflow end and includes a leaflet frame and a plurality of positioning members coupled to the leaflet frame. The leaflet frame has an undulating shape at the outflow end of the support frame and includes a plurality of commissure regions spaced apart from each other. The positioning members are disposed between the commissure regions of the leaflet frame and extend radially outwardly relative to the leaflet frame. The positioning members are configured to contact native tissue and anchor the support frame relative to the native tissue. The leaflets are coupled to the commissure regions of the leaflet frame. The leaflets are configured to allow flow in a first direction and to substantially block flow in an opposite direction.

Abstract: A prosthetic heart valve includes a support frame and a plurality of leaflets disposed inside the support frame. The support frame extends between an inflow end and an outflow end and includes a leaflet frame and a plurality of positioning members coupled to the leaflet frame. The leaflet frame has an undulating shape at the outflow end of the support frame and includes a plurality of commissure regions spaced apart from each other. The positioning members are disposed between the commissure regions of the leaflet frame and extend radially outwardly relative to the leaflet frame. The positioning members are configured to contact native tissue and anchor the support frame relative to the native tissue. The leaflets are coupled to the commissure regions of the leaflet frame. The leaflets are configured to allow flow in a first direction and to substantially block flow in an opposite direction.

Abstract: A medical device (100) comprises a container receiver unit (110) configured to receive and hold a container (120), wherein the container (120) accommodates a pharmaceutical product (125) and comprises a first communication tag (130) configured to store information regarding the pharmaceutical product (125), a reader unit (140) configured to wirelessly read the information from the first communication tag (130), and a control unit (150) configured to control the medical device (100) based on the information read from the first communication tag (130). The medical device (100) further comprises an opening or a transparent window (165) allowing to at least partially see from the outside the container (120) inserted into the container receiver unit (110), wherein the reader unit (140) comprises a first antenna unit (142, 144), and the container (120) inserted into the container receiver unit (110) is located between (i) the opening or the transparent window (165) and (ii) the first antenna unit (142, 144).

Abstract: An exemplary eyewear system includes a user interface and a composite lens. A first layer of the composite lens changes opacity in response to a signal. A second layer of the composite lens is a transparent display. The eyewear system further includes a camera, a processing device, and a memory. The processing device receives input via the user interface and, in response to the received input, sends a signal to the first layer of the composite lens to change the opacity of the first layer to cause the composite lens to be at least partially opaque, activates the camera, enhances video feed captured by the camera to increase the contrast of at least a portion of each of a plurality of frames of the video feed, and displays the enhanced video feed in real time using the second layer of the composite lens.

Abstract: The present disclosure relates to a system (100) for administering a pharmaceutical product. The system comprises a container (102) accommodating a pharmaceutical product. The container (102) comprises a wireless communication unit (112) and a memory (116) which stores an administration scheme specifically adapted to the pharmaceutical product accommodated in the container (102). The administration scheme specifies at least one administration-related parameter to be adhered to in administering the pharmaceutical product to a patient. The system further comprises a wireless communication device (104; 206; 208) configured to read the administration scheme from the memory (116) of the container (102) and to perform at least one action based on the administration scheme.

Abstract: A valve catheter is advanced through a patient's vasculature while a prosthetic heart valve is attached to flexible extensions along a distal end thereof. The valve catheter is advanced through a tubular sleeve for exposing the prosthetic heart valve and allowing the prosthetic heart valve to self-expand while the extensions remain attached to the prosthetic heart valve. A release mechanism on a handle portion is actuated for releasing the prosthetic heart valve from the extensions, thereby implanting the prosthetic heart in a native heart valve. If the operator is not satisfied with the initial expansion, the prosthetic heart valve may be reoriented before release from the extensions by retracting the prosthetic heart valve back into the tubular sleeve, adjusting the orientation of the prosthetic heart valve and then re-advancing the valve catheter from the tubular sleeve for allowing the prosthetic heart valve to re-self-expand at a more desirable location.

Abstract: The invention concerns an injector device (100), comprising access means (110, 115) configured to selectively allow and prevent a cartridge (120) storing a pharmaceutical product (122) from being removed from the injector device (100), a self-test unit (130) configured to cause a self-test of at least one of an electronic component and an electronic assembly of the injector device (100), and a control unit (140) configured to control the access means (110, 115) to allow the cartridge (120) to be removed from the injector device (100) in case the self-test has failed.

Abstract: An exemplary eyewear system includes a user interface and a composite lens. A first layer of the composite lens changes opacity in response to a signal. A second layer of the composite lens is a transparent display. The eyewear system further includes a camera, a processing device, and a memory. The processing device receives input via the user interface and, in response to the received input, sends a signal to the first layer of the composite lens to change the opacity of the first layer to cause the composite lens to be at least partially opaque, activates the camera, enhances video feed captured by the camera to increase the contrast of at least a portion of each of a plurality of frames of the video feed, and displays the enhanced video feed in real time using the second layer of the composite lens.

Abstract: A driving mechanism (100) for an injector device comprises a coil spring (10) having a proximal end (12) and a distal end (14), a spring guide (20) adapted to guide a movement of the coil spring (10), and an actuator (50, 52, 54, 56, 58, 60) adapted to cause a force on the proximal end (12) of the coil spring (10), wherein the spring guide (20) comprises a curved part (22) having a curved shape. An injector device comprises a driving mechanism (100) and a needle ejection mechanism comprising a hollow skin needle, wherein the driving mechanism (100) is adapted to cause a dispensing of a drug from a cartridge (70) through the hollow skin needle and an ejection of the hollow skin needle from the injector device.

Abstract: A needle ejection and retraction mechanism (10) comprises a needle (12), a needle hub (14) connected to the needle (12) and adapted to be displaced in a distal direction and in a proximal direction, a first spring mechanism (16) compressed to exert a force in the distal direction on the needle hub (14) and adapted to cause the needle (12) to eject in the distal direction, a second spring mechanism (18) compressed to exert a force in the proximal direction on the needle hub (14) and adapted to cause the needle (12) to retract in the proximal direction after it has been ejected in the distal direction, and an actuator (20) which is adapted to activate the exertion of the force in the distal direction on the needle hub (14) and the exertion of the force in the proximal direction on the needle hub (14).

Abstract: The present disclosure relates to a system (100) for administering a pharmaceutical product. The system comprises a container (102) accommodating a pharmaceutical product. The container (102) comprises a wireless communication unit (112) and a memory (116) which stores an administration scheme specifically adapted to the pharmaceutical product accommodated in the container (102). The administration scheme specifies at least one administration-related parameter to be adhered to in administering the pharmaceutical product to a patient. The system further comprises a wireless communication device (104; 206; 208) configured to read the administration scheme from the memory (116) of the container (102) and to perform at least one action based on the administration scheme.

Abstract: A medical device (100) comprises a container receiver unit (110) configured to receive and hold a container (120), wherein the container (120) accommodates a pharmaceutical product (125) and comprises a first communication tag (130) configured to store information regarding the pharmaceutical product (125), a reader unit (140) configured to wirelessly read the information from the first communication tag (130), and a control unit (150) configured to control the medical device (100) based on the information read from the first communication tag (130). The medical device (100) further comprises an opening or a transparent window (165) allowing to at least partially see from the outside the container (120) inserted into the container receiver unit (110), wherein the reader unit (140) comprises a first antenna unit (142, 144), and the container (120) inserted into the container receiver unit (110) is located between (i) the opening or the transparent window (165) and (ii) the first antenna unit (142, 144).

Abstract: The present disclosure relates to a system (100) for use of a pharmaceutical product. The system comprises a container (102) accommodating a pharmaceutical product, the container (102) comprising a wireless communication unit (112) and a memory (116) which stores pairing-specific information for one or more medical devices (104), and a medical device (104) enabled for wireless communication with the wireless communication unit (112) of the container (102) and configured to read the pairing-specific information from the memory (116) of the container (102) to verify whether the container (102) is permitted to be used by the medical device (104).

Abstract: A piercing mechanism for piercing a cartridge (10) comprises a cartridge container (20) adapted to receive and hold a cartridge (10) and allow a movement of the cartridge (10) from a start position via a piercing state to an end position, the cartridge (10) comprising a septum (14) covering a dispensing port (15) and a piston (12) adapted to be moved from a proximal position along an axial direction of the cartridge (10) to a distal position, a hollow needle (30) having a distal end (31) and a proximal end (32), the hollow needle (30) being immovably fixed in the piercing mechanism and adapted to pierce the septum (14) with the proximal end (32) when the cartridge (10) is moved from the start position via the piercing state to the end position, a plunger (40) adapted to cause the movement of the piston (12) when the plunger (40) is moved from a first position to a second position, wherein the second position is closer to the hollow needle (30) than the first position, and a spring mechanism (50) adapted to be

Abstract: A prosthetic heart valve includes a support frame and a plurality of leaflets disposed inside the support frame. The support frame extends between an inflow end and an outflow end and includes a leaflet frame and a plurality of positioning members coupled to the leaflet frame. The leaflet frame has an undulating shape at the outflow end of the support frame and includes a plurality of commissure regions spaced apart from each other. The positioning members are disposed between the commissure regions of the leaflet frame and extend radially outwardly relative to the leaflet frame. The positioning members are configured to contact native tissue and anchor the support frame relative to the native tissue. The leaflets are coupled to the commissure regions of the leaflet frame. The leaflets are configured to allow flow in a first direction and to substantially block flow in an opposite direction.

Abstract: A prosthetic heart valve includes a collapsible and expandable support frame extending between an inflow end and an outflow end and a plurality of commissures, wherein each commissure is formed with an elongate opening. A plurality of leaflets are supported inside the support structure and operative for allowing flow in a first direction from the inflow end to the outflow end and to substantially block flow in an opposite direction from the outflow end to the inflow end. Each of the plurality of leaflets includes tabs. The prosthetic heart valve includes at least a first panel of fabric covering the opening of a first commissure. The first panel of fabric is attached to a first tab of a first leaflet via a suture extending orthogonal to the first panel of fabric, wherein the first panel of fabric is positioned radially outwardly of the first tab.

Abstract: A prosthetic heart valve has three cusp regions positioned at an inflow end intermediate three commissure regions positioned at an outflow end thereof. A support frame including three cusp positioners is fixed with respect to a leaflet frame and located intermediate each pair of adjacent commissure regions. The valve is desirably compressible. In the aortic valve position, the cusp positioners angle outward into contact with the sinus cavities, and compress the native leaflets if they are not excised, or the aortic wall if they are.

Abstract: A prosthetic heart valve includes a collapsible and expandable support frame extending between an inflow end and an outflow end and a plurality of commissures, wherein each commis sure is formed with an elongate opening. A plurality of leaflets are supported inside the support structure and operative for allowing flow in a first direction from the inflow end to the outflow end and to substantially block flow in an opposite direction from the outflow end to the inflow end. Each of the plurality of leaflets includes tabs. The prosthetic heart valve includes at least a first panel of fabric covering the opening of a first commissure. The first panel of fabric is attached to a first tab of a first leaflet via a suture extending orthogonal to the first panel of fabric, wherein the first panel of fabric is positioned radially outwardly of the first tab.