Abstract: A heart valve prosthesis can be formed with a harvested tissue heart valve and a sewing rim that extends outwardly from the annulus of the harvested heart valve for easier attachment of the prosthesis. The heart valve prosthesis can further include a belt that extends along the annulus to provide further support to the valve annulus. A single piece of pericardial tissue can be used to form the sewing rim, belt and a collar that envelopes the edge of the annulus. The harvested heart valve prosthesis can have the diameter of its annulus adjusted using pledgeted suture prior to the application of additional support structures such as the belt, sewing rim and collar.

Abstract: Prosthetic conduits include biocompatible material formed into a generally cylindrical section and an expanded section connected to the generally cylindrical section. The conduit has a lumen extending through the generally cylindrical section and the expanded section. The biocompatible material may be tissue. The biocompatible material can include one segment or a plurality of segments joined together to form the generally cylindrical section and the expanded section. The prosthetic conduit may include a reinforcement to prevent dilation or collapse of the conduit. The reinforcement can be placed at or near the junction of a generally cylindrical section and an expanded section and/or at other locations along the conduit. The prosthetic conduit may include a prosthetic heart valve. The prosthetic conduit can include tubules to facilitate attachment of coronary arteries to the prosthetic conduit The prosthetic conduit includes two sections that are joined to form the prosthetic conduit.

Abstract: In some embodiments, prosthetic conduits include biocompatible material formed into a generally cylindrical section and an expanded section connected to the generally cylindrical section to form a conduit. The conduit has a lumen extending through the generally cylindrical section and the expanded section. In some embodiments, the biocompatible material is tissue. The biocompatible material can include one segment or a plurality of segments joined together to form the generally cylindrical section and the expanded section. In some embodiments, the prosthetic conduit includes a reinforcement to prevent unwanted dilation or collapse of the conduit. The reinforcement can be placed at or near the junction of a generally cylindrical section and an expanded section and/or at other locations along the conduit. The prosthetic conduit may or may not include a prosthetic heart valve.

Abstract: A semilunar stentless valve is formed entirely of biological tissue, and has a plurality of leaflets that are joined to form an annulus and coapt to form a one-way valve. The leaflets open fully to minimize obstruction. A narrow rim of tissue is provided over commissures where the leaflets join and around a base of the valve for a sewing ring. The valves can be sutured to heart tissue wall in a single suture row.

Abstract: A heart valve prosthesis can be formed with a harvested tissue heart valve and a sewing rim that extends outwardly from the annulus of the harvested heart valve for easier attachment of the prosthesis. The heart valve prosthesis can further include a belt that extends along the annulus to provide further support to the valve annulus. A single piece of pericardial tissue can be used to form the sewing rim, belt and a collar that envelopes the edge of the annulus. The harvested heart valve prosthesis can have the diameter of its annulus adjusted using pledgeted suture prior to the application of additional support structures such as the belt, sewing rim and collar.

Abstract: A heart valve prosthesis can be formed with a harvested tissue heart valve and a sewing rim that extends outwardly from the annulus of the harvested heart valve for easier attachment of the prosthesis. The heart valve prosthesis can further include a belt that extends along the annulus to provide further support to the valve annulus. A single piece of pericardial tissue can be used to form the sewing rim, belt and a collar that envelopes the edge of the annulus. The harvested heart valve prosthesis can have the diameter of its annulus adjusted using pledgeted suture prior to the application of additional support structures such as the belt, sewing rim and collar.

Abstract: A semilunar stentless valve is formed entirely of biological tissue, and has a plurality of leaflets that are joined to form an annulus and coapt to form a one-way valve. The leaflets open fully to minimize obstruction. A narrow rim of tissue is provided over commissures where the leaflets join and around a base of the valve for a serving ring. The valves can be sutured to heart tissue wall in a single suture row.

Abstract: A semilunar stentless valve is constructed entirely of biocompatible material, and has a plurality of leaflets that are joined to form an annulus and coapt to form a one-way valve. The leaflets open fully to minimize obstruction. A narrow rim strip overlies commissures where the leaflets join and around a base of the valve. The valve is of a conical design, flexible, easy to fit and preserves the integrity of the coronary sinuses. The valves can be implanted with a single suture row, reducing implant time significantly.

Abstract: The present invention relates to a heterologous total stentless mitral valve prosthesis for the use in mitral and tricuspid position which provides for better hemodynamic performance. This mitral valve prosthesis addresses the specific needs of flow and contractility, thereby prolonging durability. The heterologous total stentless mitral heart valve prosthesis of this present invention comprises one sewing ring, leaflets, and subvalvular apparatus having new chordal insertions which are fixed to or in between two heterologous pericardial patches. This heart valve prosthesis is obtained from heterologous mammals, such as swine, ovine, bovine, and moreover, the pericardial patches used may also be of synthetic material.

Abstract: The present invention relates to a heterologous total stentless mitral valve prosthesis for the use in mitral and tricuspid position which provides for better hemodynamic performance. This mitral valve prosthesis addresses the specific needs of flow and contractility, thereby prolonging durability. The heterologous total stentless mitral heart valve prosthesis of this present invention comprises one sewing ring, leaflets, and subvalvar apparatus having new chordal insertions which are fixed between two heterologous pericardial patches. This heart valve prosthesis is obtained from heterologous mammals, such as swine, ovine, bovine, and moreover, the pericardial patches used may also be of synthetic material.

Abstract: The present invention relates to a heterologous total stentless mitral valve prosthesis for the use in mitral and tricuspid position which provides for better hemodynamic performance. This mitral valve prosthesis addresses the specific needs of flow and contractility, thereby prolonging durability. The heterologous total stentless mitral heart valve prosthesis of this present invention comprises one sewing ring, leaflets, and subvalvular apparatus having new chordal insertions which are fixed to or in between two heterologous pericardial patches. This heart valve prosthesis is obtained from heterologous mammals, such as swine, ovine, bovine, and moreover, the pericardial patches used may also be of synthetic material.