Patents by Inventor Mariolina Salio

Mariolina Salio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analogs of alpha galactosylceramide and uses thereof
    Patent number: 8334408
    Abstract: Compounds of formula wherein the variables are defined in the specification, are used in compositions which stimulate T cell responses.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: December 18, 2012
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Vincenzo Cerundolo, Richard Schmidt, Gopal Reddy, Rengarajan Balamurugan, Gerd Ritter, Gurdyal Besra, Mariolina Salio, Jonathan Silk
  • ANALOGS OF ALPHA GALACTOSYLCERAMIDE AND USES THEREOF
    Publication number: 20120269857
    Abstract: Compounds of formula wherein the variables are defined in the specification, are used in compositions which stimulate T cell responses.
    Type: Application
    Filed: May 4, 2012
    Publication date: October 25, 2012
    Inventors: Vincenzo CERUNDOLO, Richard Schmidt, Gopal Reddy, Rengarajan Balamurugan, Gerd Ritter, Gurdyal Besra, Mariolina Salio, Jonathan Silk
  • Analogs of alpha galactosylceramide and uses thereof
    Patent number: 8188313
    Abstract: Compounds of formula wherein the variable are defined in the specification, are used in compositions which stimulate T cell responses.
    Type: Grant
    Filed: September 13, 2011
    Date of Patent: May 29, 2012
    Assignees: The University of Birmingham, Chancellor Masters and Scholars of the University of Oxford, Ludwig Institute for Cancer Research
    Inventors: Vincenzo Cerundolo, Richard Schmidt, Gopal Reddy, Rengarajan Balamurugan, Gerd Ritter, Gurdyal Besra, Mariolina Salio, Jonathan Silk
  • ANALOGS OF ALPHA GALACTOSYLCERAMIDE AND USES THEREOF
    Publication number: 20120034269
    Abstract: Compounds of formula wherein the variable are defined in the specification, are used in compositions which stimulate T cell responses.
    Type: Application
    Filed: September 13, 2011
    Publication date: February 9, 2012
    Inventors: Vincenzo Cerundolo, Richard Schmidt, Gopal Reddy, Rengarajan Balamurugan, Gerd Ritter, Gurdyal Besra, Mariolina Salio, Jonathan Silk
  • Analogs of alpha galactosyceramide and uses thereof
    Patent number: 8039670
    Abstract: There are disclosed compound of formula I, in which R1 represents a hydrophobic moiety adapted to occupy the C? channel of human CDId, R2 represents a hydrophobic moiety adapted to occupy the A? channel of human CDId, such that R1 fills at least at least 30% of the occupied volume of the C? channel compared to the volume occupied by the terminal nC14H29 of the sphingosine chain of ?-galactosylceramide when bound to human CDId and R2 fills at least 30% of the occupied volume of the A? channel compared to the volume occupied by the terminal nC25H51 of the acyl chain of ?-galactosylceramide when bound to human CDId R3 represents hydrogen or OH, Ra and Rb each represent hydrogen and in addition, when R3 represents hydrogen, Ra and Rb together may form a single bond, X represents or —CHA(CHOH)nY or —P(=0)(0?)0CH2(CH0H)mY, in which Y represents CHB1B2, n represents an integer from 1 to 4, m represents 0 or 1, A årepresents hydrogen, one of B1 and B2 represents H, OH or phenyl, and the other represents hydrogen or o
    Type: Grant
    Filed: October 25, 2006
    Date of Patent: October 18, 2011
    Assignees: Ludwig Institute for Cancer Research, Chancellor Master and Scholars of the University of Oxford, The University of Birmingham
    Inventors: Vincenzo Cerundolo, Richard Schmidt, Gopal Reddy, Rengarajan Balamurugan, Gerd Ritter, Gurdyal Besra, Mariolina Salio, Jonathan Silk