Patents by Inventor Marion F. Hawthorne

Marion F. Hawthorne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210047289
    Abstract: Disclosed herein are carborane derivatives of Formula I or Formula V, or a pharmaceutically acceptable salt thereof, for use as neuromuscular blocking agents. The carborane is substituted with two cationic functional groups selected from amines that form ammonium cations, ethers and/or alcohols that form oxonium cations, sulfides and/or thiols that form sulfonium cations, and phosphanes and/or phosphines that form phosphonium cations.
    Type: Application
    Filed: March 27, 2019
    Publication date: February 18, 2021
    Inventors: George R. Kracke, Lalit N. Goswami, Marion F Hawthorne, Satish S. Jalisatgi
  • Patent number: 4824659
    Abstract: An antibody or antibody fragment is modified by chemical linkage to a synthetic poly(amide/urea/thiourea) which contains a plurality of boron atoms or other functional groups, conferring upon the resultant conjugate desirable properties as a diagnostic and/or therapeutic agent. In a preferred embodiment, boron-containing groups are conjugated to the antibody/fragment such that the resultant conjugate contains 50-2000 boron atoms, with about 96% Boron-10 isotope content, to produce conjugates useful for neutron-activated radiotherapy of tumors or pathological lesions.
    Type: Grant
    Filed: June 7, 1985
    Date of Patent: April 25, 1989
    Assignee: Immunomedics, Inc.
    Inventor: Marion F. Hawthorne
  • Patent number: 4001058
    Abstract: 3. An ester of the formula ##STR1## in which n is 1 to 2 and R is a radical selected from the group consisting of(HDCH.sub.2).sub.2 CH--,(hd).sub.2 ch--,hdch.sub.2 --,hd(ch.sub.2).sub.2 --,hd(ch.sub.2).sub.3 --,hd(ch.sub.2).sub.4 --,hd(ch.sub.2).sub.5 --,and(CH.sub.3 D).sub.2 CH--in which formula -D- represents --C.sub.2 B.sub.10 H.sub.10 --. 12. Polymers of the formula ##STR2## in which n is 1 to 2, R is a radical selected from the group consisting of(HDCH.sub.2).sub.2 CH--,(hd).sub.2 ch--,hdch.sub.2 --,hd(ch.sub.2).sub.2 --,hd(ch.sub.2).sub.3 --,hd(ch.sub.2).sub.4 --,hd(ch.sub.2).sub.5 --,and(CH.sub.3 D).sub.2 CH--,x is about 5 to 3000, and -D- represents --C.sub.2 B.sub.10 H.sub.10 --. 15. Polymers of claim 12 containing from 5 to 30% on the weight of the polymer of a nitrato ester of an alcohol containing 1 to 10 carbon atoms and having 1 to 3 hydroxyl groups.
    Type: Grant
    Filed: March 10, 1961
    Date of Patent: January 4, 1977
    Assignee: Rohm and Haas Company
    Inventor: Marion F. Hawthorne
  • Patent number: 3976596
    Abstract: A family of stable hydrido-rhodium and iridium carboranes are described which are effective catalysts for the homogeneous hydrogenation, isomerization and hydroformylation of olefins and the hydrosilylation of ketones.
    Type: Grant
    Filed: March 26, 1975
    Date of Patent: August 24, 1976
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Marion F. Hawthorne, Timm E. Paxson