Patents by Inventor Marissa N. RYLANDER

Marissa N. RYLANDER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fiber array for optical imaging and therapeutics
    Patent number: 10220124
    Abstract: The present invention relates to the field of optical imaging and therapeutics. More particularly, embodiments of the present invention provide minimally-invasive Fiberoptic Microneedle Devices (FMDs) for light-based therapeutics, which physically penetrate tissue and deliver light directly into the target area below the skin surface. Embodiments of the invention enable depth-selective and deep photothermal therapeutics and include methods of treating cancer, methods of re-shaping or removing adipose tissue, and methods of delivering drugs or co-delivering drugs and energy to selected tissue.
    Type: Grant
    Filed: February 28, 2012
    Date of Patent: March 5, 2019
    Assignee: VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.
    Inventors: Christopher Rylander, Mehmet A. Kosoglu, Robert L. Hood, John L. Robertson, John H. Rossmeisl, David C. Grant, Marissa N. Rylander
  • Irreversible electroporation using nanoparticles
    Patent number: 8814860
    Abstract: The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) to cause cell death in treated tumors. In embodiments, the methods comprise the use of high aspect ratio nanoparticles with or without modified surface chemistry.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: August 26, 2014
    Assignee: Virginia Tech Intellectual Properties, Inc.
    Inventors: Rafael V. Davalos, Marissa N. Rylander, Christopher B. Arena, Yong Woo Lee
  • FIBER ARRAY FOR OPTICAL IMAGING AND THERAPEUTICS
    Publication number: 20130338627
    Abstract: The present invention relates to the field of optical imaging and therapeutics. More particularly, embodiments of the present invention provide minimally-invasive Fiberoptic Microneedle Devices (FMDs) for light-based therapeutics, which physically penetrate tissue and deliver light directly into the target area below the skin surface. Embodiments of the invention enable depth-selective and deep photothermal therapeutics and include methods of treating cancer, methods of re-shaping or removing adipose tissue, and methods of delivering drugs or co-delivering drugs and energy to selected tissue.
    Type: Application
    Filed: February 28, 2012
    Publication date: December 19, 2013
    Inventors: Christopher Rylander, Mehmet A. Kosoglu, Robert L. Hood, John L Robertson, John H. Rossmeisl, David C. Grant, Marissa N. Rylander
  • Irreversible Electroporation using Nanoparticles
    Publication number: 20130281968
    Abstract: The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) to cause cell death in treated tumors. In embodiments, the methods comprise the use of high aspect ratio nanoparticles with or without modified surface chemistry.
    Type: Application
    Filed: June 17, 2013
    Publication date: October 24, 2013
    Inventors: Rafael V. DAVALOS, Marissa N. RYLANDER, Christopher B. ARENA
  • Irreversible electroporation using nanoparticles
    Patent number: 8465484
    Abstract: The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) to cause cell death in treated tumors. In embodiments, the methods comprise the use of high aspect ratio nanoparticles with or without modified surface chemistry.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: June 18, 2013
    Assignee: Virginia Tech Intellectual Properties, Inc.
    Inventors: Rafael V. Davalos, Marissa N. Rylander, Christopher B. Arena
  • IRREVERSIBLE ELECTROPORATION USING NANOPARTICLES
    Publication number: 20130096485
    Abstract: The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) to cause cell death in treated tumors. In embodiments, the methods comprise the use of high aspect ratio nanoparticles with or without modified surface chemistry.
    Type: Application
    Filed: October 30, 2009
    Publication date: April 18, 2013
    Inventors: Rafael V. DAVALOS, Marissa N. RYLANDER, Christopher B. ARENA
  • IRREVERSIBLE ELECTROPORATION USING NANOPARTICLES
    Publication number: 20100331758
    Abstract: The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) to cause cell death in treated tumors. In embodiments, the methods comprise the use of high aspect ratio nanoparticles with or without modified surface chemistry.
    Type: Application
    Filed: October 30, 2009
    Publication date: December 30, 2010
    Inventors: Rafael V. DAVALOS, Marissa N. RYLANDER, Christopher B. ARENA