Patents by Inventor Maritza MAYORGA

Maritza MAYORGA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF ISCHEMIA AND CARDIOMYOPATHY
    Publication number: 20240082357
    Abstract: Provided herein are methods to promote tissue healing, to treat tissue injury or to treat a condition related to tissue injury comprising administering to a subject in need thereof an effective amount of one or both of: a CAMKK1 polypeptide or an equivalent thereof; or an SDF-1 polypeptide or an equivalent thereof, in the presence of CXCR4 polypeptide expression, wherein the effective amount is an amount that induces exosome production, secretion and/or function in the subject. Recombinant stem cells are also provided that overexpress one or both of a CAMKK1 protein or polypeptide and/or an SDF-1 protein or polypeptides. The stem cells and products produced from them are useful to treat ischemic or inflammatory conditions as well as to promote tissue healing.
    Type: Application
    Filed: November 22, 2023
    Publication date: March 14, 2024
    Applicants: SUMMA HEALTH, NORTHEAST OHIO MEDICAL UNIVERSITY
    Inventors: Marc S. PENN, Maritza MAYORGA, Matthew KIEDROWSKI
  • CAMKK1 AS A NOVEL REGENERATIVE THERAPEUTIC
    Publication number: 20220233653
    Abstract: Disclosed herein are methods of treating an ischemic or inflammatory condition in an organ or tissue of a patient comprising inducing an increase of the level of CAMKK1 in said organ or tissue.
    Type: Application
    Filed: February 8, 2022
    Publication date: July 28, 2022
    Applicants: SUMMA HEALTH, NORTHEAST OHIO MEDICAL UNIVERSITY
    Inventors: Marc S. PENN, Matthew Kiedrowski, Maritza Mayorga
  • CAMKK1 as a novel regenerative therapeutic
    Patent number: 11273208
    Abstract: Disclosed herein are methods of treating an ischemic or inflammatory condition in an organ or tissue of a patient comprising inducing an increase of the level of CAMKK1 in said organ or tissue.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: March 15, 2022
    Assignees: Summa Health, Northeast Ohio Medical University
    Inventors: Marc S. Penn, Matthew Kiedrowski, Maritza Mayorga
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF ISCHEMIA AND CARDIOMYOPATHY
    Publication number: 20210113662
    Abstract: Provided herein are methods to promote tissue healing, to treat tissue injury or to treat a condition related to tissue injury comprising administering to a subject in need thereof an effective amount of one or both of: a CAMKK1 polypeptide or an equivalent thereof; or an SDF-1 polypeptide or an equivalent thereof, in the presence of CXCR4 polypeptide expression, wherein the effective amount is an amount that induces exosome production, secretion and/or function in the subject. Recombinant stem cells are also provided that overexpress one or both of a CAMKK1 protein or polypeptide and/or an SDF-1 protein or polypeptides. The stem cells and products produced from them are useful to treat ischemic or inflammatory conditions as well as to promote tissue healing.
    Type: Application
    Filed: April 17, 2019
    Publication date: April 22, 2021
    Applicants: SUMMA HEALTH, NORTHEAST OHIO MEDICAL UNIVERSITY
    Inventors: Marc S. PENN, Maritza MAYORGA, Matthew KIEDROWSKI
  • CAMKK1 AS A NOVEL REGENERATIVE THERAPEUTIC
    Publication number: 20170340712
    Abstract: Disclosed herein are methods of treating an ischemic or inflammatory condition in an organ or tissue of a patient comprising inducing an increase of the level of CAMKK1 in said organ or tissue.
    Type: Application
    Filed: May 31, 2017
    Publication date: November 30, 2017
    Applicants: SUMMA HEALTH, NORTHEAST OHIO MEDICAL UNIVERSITY
    Inventors: Marc S. PENN, Matthew KIEDROWSKI, Maritza MAYORGA