Patents by Inventor Marius ARDELEANU

Marius ARDELEANU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11845800
    Abstract: The present invention provides methods for treating or preventing asthma and associated conditions in a patient. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: December 19, 2023
    Assignees: SANOFI BIOTECHNOLOGY, REGENERON PHARMACEUTICALS, INC.
    Inventors: Marius Ardeleanu, Namita A. Gandhi, Neil Graham, Stephane C. Kirkesseli, Sudeep Kundu, Ross E. Rocklin, Allen Radin, Steven P. Weinstein, Jennifer Davidson Hamilton, Jeffrey Ming
  • Publication number: 20230357416
    Abstract: The present invention provides methods for treating, preventing or ameliorating skin infections, including bacterial and viral infections. In certain embodiments, the invention provides methods to reduce skin infection in a patient with atopic dermatitis (AD). Also provided are methods for improving skin barrier function, and methods for reducing the risk of inflammation due to microbial infection in a patient in need thereof. The methods of the present invention comprise administering to a patient in need thereof a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody.
    Type: Application
    Filed: February 6, 2023
    Publication date: November 9, 2023
    Inventors: Neil GRAHAM, Marius ARDELEANU, Allen RADIN, Jennifer D. HAMILTON, Ariel TEPER
  • Patent number: 11603408
    Abstract: The present invention provides methods for treating, preventing or ameliorating skin infections, including bacterial and viral infections. In certain embodiments, the invention provides methods to reduce skin infection in a patient with atopic dermatitis (AD). Also provided are methods for improving skin barrier function, and methods for reducing the risk of inflammation due to microbial infection in a patient in need thereof. The methods of the present invention comprise administering to a patient in need thereof a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody.
    Type: Grant
    Filed: May 28, 2019
    Date of Patent: March 14, 2023
    Assignees: Regeneron Pharmaceuticals, Inc., Sanofi Biotechnology
    Inventors: Neil Graham, Marius Ardeleanu, Allen Radin, Jennifer D. Hamilton, Ariel Teper
  • Publication number: 20230058395
    Abstract: The present invention provides methods for treating atopic dermatitis (AD). Also provided are methods for improving one or more AD-associated parameter(s), and methods for decreasing the level of at least one AD-associated biomarker in a subject in need thereof. The methods of the present invention comprise administering to a subject in need thereof a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody.
    Type: Application
    Filed: September 23, 2022
    Publication date: February 23, 2023
    Inventors: Marius ARDELEANU, Neil GRAHAM, Jennifer Davidson HAMILTON, Stephane C. KIRKESSELI, Sudeep KUNDU, Jeffrey MING, Allen RADIN, Ross E. ROCKLIN, Steven Paul WEINSTEIN
  • Publication number: 20190367622
    Abstract: The present invention provides methods for treating, preventing or ameliorating skin infections, including bacterial and viral infections. In certain embodiments, the invention provides methods to reduce skin infection in a patient with atopic dermatitis (AD). Also provided are methods for improving skin barrier function, and methods for reducing the risk of inflammation due to microbial infection in a patient in need thereof. The methods of the present invention comprise administering to a patient in need thereof a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody.
    Type: Application
    Filed: May 28, 2019
    Publication date: December 5, 2019
    Inventors: Neil GRAHAM, Marius ARDELEANU, Allen RADIN, Jennifer D. HAMILTON, Ariel TEPER
  • Patent number: 10370449
    Abstract: The present invention provides methods for treating, preventing or ameliorating skin infections, including bacterial and viral infections. In certain embodiments, the invention provides methods to reduce skin infection in a patient with atopic dermatitis (AD). Also provided are methods for improving skin barrier function, and methods for reducing the risk of inflammation due to microbial infection in a patient in need thereof. The methods of the present invention comprise administering to a patient in need thereof a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: August 6, 2019
    Assignees: Regeneron Pharmaceuticals, Inc., Sanofi Biotechnology
    Inventors: Neil Graham, Marius Ardeleanu, Allen Radin, Jennifer D. Hamilton, Ariel Teper
  • Publication number: 20180016343
    Abstract: The present invention provides methods for treating or preventing asthma and associated conditions in a patient. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody.
    Type: Application
    Filed: June 20, 2017
    Publication date: January 18, 2018
    Inventors: Marius Ardeleanu, Namita A. Gandhi, Neil Graham, Stephane C. Kirkesseli, Sudeep Kundu, Ross E. Rocklin, Allen Radin, Steven P. Weinstein, Jennifer Davidson Hamilton, Jeffrey Ming
  • Publication number: 20170333557
    Abstract: The present invention provides methods for treating atopic dermatitis (AD). Also provided are methods for improving one or more AD-associated parameter(s), and methods for decreasing the level of at least one AD-associated biomarker in a subject in need thereof. The methods of the present invention comprise administering to a subject in need thereof a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody.
    Type: Application
    Filed: May 31, 2017
    Publication date: November 23, 2017
    Inventors: Marius ARDELEANU, Neil GRAHAM, Jennifer Davidson HAMILTON, Stephane C. KIRKESSELI, Sudeep KUNDU, Jeffrey MING, Allen RADIN, Ross E. ROCKLIN, Steven Paul WEINSTEIN
  • Patent number: 9574004
    Abstract: The present invention provides methods for treating or preventing asthma and associated conditions in a patient. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody.
    Type: Grant
    Filed: August 20, 2013
    Date of Patent: February 21, 2017
    Assignees: Sanofi Biotechnology, Regeneron Pharmaceuticals, Inc.
    Inventors: Marius Ardeleanu, Namita A. Gandhi, Neil Graham, Stephanie C. Kirkesseli, Sudeep Kundu, Ross E. Rocklin, Allen Radin, Steven P. Weinstein, Jennifer Davidson Hamilton, Jeffrey Ming
  • Publication number: 20150246973
    Abstract: The present invention provides methods for treating, preventing or ameliorating skin infections, including bacterial and viral infections. In certain embodiments, the invention provides methods to reduce skin infection in a patient with atopic dermatitis (AD). Also provided are methods for improving skin barrier function, and methods for reducing the risk of inflammation due to microbial infection in a patient in need thereof. The methods of the present invention comprise administering to a patient in need thereof a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody.
    Type: Application
    Filed: February 26, 2015
    Publication date: September 3, 2015
    Inventors: Neil Graham, Marius Ardeleanu, Allen Radin, Jennifer D. Hamilton, Ariel Teper
  • Publication number: 20140072583
    Abstract: The present invention provides methods for treating atopic dermatitis (AD). Also provided are methods for improving one or more AD-associated parameter(s), and methods for decreasing the level of at least one AD-associated biomarker in a subject in need thereof. The methods of the present invention comprise administering to a subject in need thereof a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody.
    Type: Application
    Filed: September 4, 2013
    Publication date: March 13, 2014
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Marius ARDELEANU, Neil GRAHAM, Jennifer Davidson HAMILTON, Stephane C. KIRKESSELI, Sudeep KUNDU, Jeffrey MING, Allen RADIN, Ross E. ROCKLIN, Steven Paul WEINSTEIN
  • Publication number: 20140056920
    Abstract: The present invention provides methods for treating or preventing asthma and associated conditions in a patient. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody.
    Type: Application
    Filed: August 20, 2013
    Publication date: February 27, 2014
    Applicants: REGENERON PHARMACEUTICALS, INC., SANOFI
    Inventors: Marius ARDELEANU, Namita A. GANDHI, Neil GRAHAM, Stephane C. KIRKESSELI, Sudeep KUNDU, Ross E. ROCKLIN, Allen RADIN, Steven P. WEINSTEIN, Jennifer Davidson HAMILTON, Jeffrey MING