Patents by Inventor Mariusz G. Banaszczyk

Mariusz G. Banaszczyk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Arginine analogs, and methods for their synthesis and use
    Patent number: 7879979
    Abstract: The present invention relates to novel arginine analogs, and methods for their synthesis and use. Such analogs are designed to provide a protected or free thiol (—SH) group, thereby providing a convenient linkage chemistry for coupling to a suitable group on a target such as a protein, polypeptide, detectable label or solid phase, and at a site distal to the guanidino group. Arginine analog conjugates are useful for generating antibodies that can bind specifically with dimethylarginine, which can be detected using such antibodies in immunoassays.
    Type: Grant
    Filed: January 19, 2006
    Date of Patent: February 1, 2011
    Assignee: Alere International
    Inventors: Kenneth F. Buechler, Mariusz G. Banaszczyk, Joseph Barry Noar, Violeta Dinauer
  • Arginine Analogs, and Methods for Their Synthesis and Use
    Publication number: 20080293920
    Abstract: The present invention relates to novel arginine analogs, and methods for their synthesis and use. Such analogs are designed to provide a protected or free thiol (—SH) group, thereby providing a convenient linkage chemistry for coupling to a suitable group on a target such as a protein, polypeptide, detectable label or solid phase, and at a site distal to the guanidino group. Arginine analog conjugates are useful for generating antibodies that can bind specifically with dimethylarginine, which can be detected using such antibodies in immunoassays.
    Type: Application
    Filed: January 19, 2006
    Publication date: November 27, 2008
    Inventors: Kenneth F. Buechler, Mariusz G. Banaszczyk, Joseph Barry Noar, Violeta Dinauer
  • N-aryl-carbamic acid ester-derived and valeric acid ester-derived cross-linkers and conjugates, and methods for their synthesis and use
    Patent number: 6967107
    Abstract: The present invention describes carbamic acid ester-derived and valeric acid ester-derived polyfunctional cross-linker molecules, and methods for their synthesis and use. The inclusion of polymeric moieties such as poly(alkylene oxide) in the cross-linkers of the present invention can provide advantageous solubility properties in aqueous environments. Such cross-linkers may be used to form conjugates for use in a variety of assay formats.
    Type: Grant
    Filed: March 14, 2005
    Date of Patent: November 22, 2005
    Assignee: Biosite, Inc.
    Inventors: Kenneth F. Buechler, Mariusz G. Banaszczyk, Joseph Barry Noar
  • N-aryl-carbamic acid ester-derived and valeric acid ester-derived cross-linkers and conjugates, and methods for their synthesis and use
    Patent number: 6887952
    Abstract: The present invention describes carbamic acid ester-derived and valeric acid ester-derived polyfunctional cross-linker molecules, and methods for their synthesis and use. The inclusion of polymeric moieties such as poly(alkylene oxide) in the cross-linkers of the present invention can provide advantageous solubility properties in aqueous environments. Such cross-linkers may be used to form conjugates for use in a variety of assay formats.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: May 3, 2005
    Assignee: Biosite, Inc.
    Inventors: Kenneth F. Buechler, Mariusz G. Banaszczyk, Joseph Barry Noar