Patents by Inventor Mark A. Haxell

Mark A. Haxell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of rumen acidosis with alpha-amylase inhibitors
    Publication number: 20050233983
    Abstract: The invention described herein relates to: the use of an effective inhibitor of a bacterial ?-amylase and/or ?-glucosidase in the manufacture of a composition for the treatment of rumen acidosis; a method of treatment of rumen acidosis which comprises administration of an effective amount of an effective inhibitor of a bacterial ?-amylase and/or ?-glucosidase to a ruminant; a formulation suitable for the treatment of rumen acidosis in an animal which comprises an effective inhibitor of a bacterial ?-amylase and/or ?-glucosidase in admixture with a suitable excipient, diluent or carrier selected with regard to the intended route of administration and standard pharmaceutical/veterinary/farming practice; screening methods useful in the identification of a suitable inhibitor of a bacterial ?-amylase and/or ?-glucosidase for the treatment of acidosis in a ruminant; a process for improving ruminant milk quality and/or quantity which comprises treatment of a ruminant with an effective amount of an inhibitor of bact
    Type: Application
    Filed: December 30, 2004
    Publication date: October 20, 2005
    Inventors: Bernard Banks, Mark Haxell, Graham Lunn, Michael Pacey, Lee Roberts
  • Process for producing antiparasitic macrolide antibiotics
    Patent number: 5589366
    Abstract: The present invention relates to certain antibiotic compounds, designated N787-182 compounds herein and derivatives thereof, which are antiparasitic agents, active against insect pests, acari, free-living nematodes and endo- and ectoparasites. This invention also relates to pharmaceutical and other compositions comprising such compounds, methods of using such compounds, the microorganism Streptomyces hygroscopicus ATCC 53718 and mutants or genetically transformed or recombinant form thereof, and processes for producing such compounds.
    Type: Grant
    Filed: November 9, 1995
    Date of Patent: December 31, 1996
    Assignee: Pfizer Inc.
    Inventors: Mark A. Haxell, David A. Perry, Hiroshi Maeda, Junsuke Tone
  • Biologically pure culture of Streptomyces hygroscopicus ATCC 53718 capable of producing antibiotic compounds
    Patent number: 5573946
    Abstract: The present invention relates to certain antibiotic compounds, designated N787-182 compounds herein and derivatives thereof, which are antiparasitic agents, active against insect pests, acari, free-living nematodes and endo- and ectoparasites. This invention also relates to pharmaceutical and other compositions containing such compounds, methods of using such compounds, the microorganism Streptomyces hygroscopicus ATCC 53718 and mutants or genetically transformed or recombinant form thereof, and processes for producing such compounds.
    Type: Grant
    Filed: November 7, 1995
    Date of Patent: November 12, 1996
    Assignee: Pfizer Inc.
    Inventors: Mark A. Haxell, David A. Perry, Hiroshi Maeda, Junsuke Tone
  • Antiparasitic macrolide antiobiotics
    Patent number: 5510372
    Abstract: The present invention relates to certain antibiotic compounds, designated N787-182 compounds herein and derivatives thereof, which are antiparasitic agents, active against insect pest, acari, free-living nematodes and endo- and ectoparasites. This invention also relates to pharmaceutical and other compositions comprising such compounds, methods of using such compounds, the microorganism Streptomyces hygroscopicus ATCC 53718 and mutants or genetically transformed or recombinant form thereof, and processes for producing such compounds.
    Type: Grant
    Filed: January 27, 1995
    Date of Patent: April 23, 1996
    Assignee: Pfizer Inc
    Inventors: Mark A. Haxell, David A. Perry, Hiroshi Maeda, Junsuke Tone
  • Process for the production of macrolide compounds
    Patent number: 5378617
    Abstract: A process for the production of a compound of formula (I) ##STR1## which comprises cultivating a microorganism of the genus Streptomyces capable of producing the compound of formula (I) in the presence of one or more fatty acids and/or salts, esters and amides of these acids, whereby the compound of formula (I) is produced, and if desired isolating the said compound. The fatty acid increases the yield of the formula (I) compound and is preferably isobutyric or valeric acid.
    Type: Grant
    Filed: August 24, 1992
    Date of Patent: January 3, 1995
    Assignee: American Cyanamid Company
    Inventors: Martin Todd, Mark A. Haxell, Gordon C. Lawrence