Patents by Inventor Mark A. Helle

Mark A. Helle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PRODUCTION OF DELTA-9-TETRAHYDROCANNABINOL
    Publication number: 20100069651
    Abstract: The present invention relates to a process for preparation of a delta-9-tetrahydrocannabinol compound or derivative thereof involving treating a first intermediate compound with an organoaluminum-based Lewis acid catalyst, under conditions effective to produce the delta-9-tetrahydrocannabinol compound or derivative thereof. Another aspect of the present invention relates to a process for preparation of a cannabidiol or cannabidiolate compound involving reacting a first starting compound with a second starting compound in the presence of a metal triflate catalyst, under conditions effective to form the cannabidiol or cannabidiolate compound. The present invention also relates to a compound of the formula: where R8, R9, and R10 are the same or different and independently selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, or halo, with R1, R2, and R3 defined herein.
    Type: Application
    Filed: November 25, 2009
    Publication date: March 18, 2010
    Applicant: ALBANY MOLECULAR RESEARCH, INC.
    Inventors: David C. BURDICK, Steven J. COLLIER, Frédéric JOS, Betina BIOLATTO, Bernhard J. PAUL, Harold MECKLER, Mark A. HELLE, Alicia J. HABERSHAW
  • Process for production of delta-9-tetrahydrocannabinol
    Patent number: 7674922
    Abstract: The present invention relates to a process for preparation of a delta-9-tetrahydrocannabinol compound or derivative thereof involving treating a first intermediate compound with an organoaluminum-based Lewis acid catalyst, under conditions effective to produce the delta-9-tetrahydrocannabinol compound or derivative thereof. Another aspect of the present invention relates to a process for preparation of a cannabidiol or cannabidiolate compound involving reacting a first starting compound with a second starting compound in the presence of a metal triflate catalyst, under conditions effective to form the cannabidiol or cannabidiolate compound. The present invention also relates to a compound of the formula: where R8, R9, and R10 are the same or different and independently selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, or halo, with R1, R2, and R3 defined herein.
    Type: Grant
    Filed: September 28, 2006
    Date of Patent: March 9, 2010
    Assignee: Albany Molecular Research, Inc.
    Inventors: David C. Burdick, Steven J. Collier, Frédéric Jos, Betina Biolatto, Bernhard J. Paul, Harold Meckler, Mark A. Helle, Alicia J. Habershaw
  • Process for production of delta-9- tetrahydrocannabinol
    Publication number: 20070093665
    Abstract: The present invention relates to a process for preparation of a delta-9-tetrahydrocannabinol compound or derivative thereof involving treating a first intermediate compound with an organoaluminum-based Lewis acid catalyst, under conditions effective to produce the delta-9-tetrahydrocannabinol compound or derivative thereof. Another aspect of the present invention relates to a process for preparation of a cannabidiol or cannabidiolate compound involving reacting a first starting compound with a second starting compound in the presence of a metal triflate catalyst, under conditions effective to form the cannabidiol or cannabidiolate compound. The present invention also relates to a compound of the formula: where R8, R9, and R10 are the same or different and independently selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, or halo, with R1, R2, and R3 defined herein.
    Type: Application
    Filed: September 28, 2006
    Publication date: April 26, 2007
    Applicant: AMR Technology, Inc.
    Inventors: David Burdick, Steven Collier, Frederic Jos, Betina Biolatto, Bernhard Paul, Harold Meckler, Mark Helle, Alicia Habershaw
  • Method for making 24(S)-hydroxyvitamin D2
    Patent number: 6359012
    Abstract: The invention provides a method for making 24(S)-hydroxyvitamin D2 which is a stereospecific synthesis.
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: March 19, 2002
    Assignee: Bone Care International, Inc.
    Inventors: Harold Meckler, Mark A. Helle, William B. Geiss, Brian T. Gregg
  • Dye compositions for polyamides
    Patent number: 5456727
    Abstract: The invention is a dye composition containing two or more dyes of the vinyl sulfone type which can be used in combination to dye polyamide substrates. Preferably the dye compositions of the invention contain at least three dyes of different primary colors.
    Type: Grant
    Filed: May 24, 1994
    Date of Patent: October 10, 1995
    Assignee: Hoechst Celanese Corporation
    Inventors: Walter Heimling, Mark Helle, Kerry Proulx, Leslie McIntosh, Philomen DeCroos
  • High temperature process for preparing fiber reactive dyes
    Patent number: 5350838
    Abstract: A process for preparing monoazo dyes by coupling a aromatic diazonium salt with an amino-4-hydroxy-naphthalene sulfonic acid derivative at a temperature of 40.degree.-85.degree. C. The process of the invention provides a isomerically purer dye.
    Type: Grant
    Filed: February 8, 1993
    Date of Patent: September 27, 1994
    Assignee: Hoechst Celanese Corporation
    Inventors: Mark A. Helle, Walter Helmling
  • Sport goggle strap cover
    Patent number: D387797
    Type: Grant
    Filed: March 28, 1994
    Date of Patent: December 16, 1997
    Assignee: Summit Ski Wear
    Inventors: Todd R. Alcock, Mark A. Helle, Lisa A. White