Patents by Inventor Mark A. Mellon
Mark A. Mellon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9206444Abstract: The present invention is directed to a yeast strain, or strains, secreting a full suite, or any subset of that full suite, of enzymes to hydrolyze corn starch, corn fiber, lignocellulose, (including enzymes that hydrolyze linkages in cellulose, hemicellulose, and between lignin and carbohydrates) and to utilize pentose sugars (xylose and arabinose). The invention is also directed to the set of proteins that are well expressed in yeast for each category of enzymatic activity. The resulting strain, or strains can be used to hydrolyze starch and cellulose simultaneously. The resulting strain, or strains can be also metabolically engineered to produce less glycerol and uptake acetate. The resulting strain, or strains can also be used to produce ethanol from granular starch without liquefaction.Type: GrantFiled: February 12, 2014Date of Patent: December 8, 2015Assignees: Lallemand Hungary Liquidity Management LLC, Stellenbosch UniversityInventors: Elena Brevnova, John E. McBride, Erin Wiswall, Kevin S. Wenger, Nicky Caiazza, Heidi Hau, Aaron Argyros, Frank Agbogbo, Charles F. Rice, Trisha Barrett, John S. Bardsley, Abigail Foster, Anne K. Warner, Mark Mellon, Ryan Skinner, Indraneel Shikhare, Riaan Den Haan, Chhayal V. Gandhi, Alan Belcher, Vineet B. Rajgarhia, Allan C. Froehlich, Kristen M. Deleault, Emily Stonehouse, Shital A. Tripathi, Jennifer Gosselin, Yin-Ying Chiu, Haowen Xu
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Patent number: 9102955Abstract: Host cells, comprising Kluveryomyces expressing heterologous cellulases produce ethanol from cellulose In addition, multiple host cells expressing different heterlogous cellulases can be co-cultured together and used to produce ethanol from cellulose The recombinant yeast strains and co-cultures of the yeast strains can be used to produce ethanol on their own, or can also be used in combination with externally added cellulases to increase the efficiency of sacchanfication and fermentation processes.Type: GrantFiled: November 23, 2009Date of Patent: August 11, 2015Assignee: Lallemand Hungary Liquidity Management LLCInventors: John McBride, Elena Brevnova, Mark Mellon, Allan Froehlich, Kristen Deleault, Vineet Rajgarhia, Riaan Den Haan, Merja Penttila, Marja Ilmen, Matti Siika-Aho, Jaana Uusitalo, Emily A. Stonehouse, Alan Gilbert, Haowen Xu, Deidre Willes, John Bardsley, Anu Koivula, Sanni Voutilainen
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Publication number: 20150024438Abstract: The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be codon-optimized and expressed in yeast host cells, such as the yeast Saccharomyces cerevisiae. The cellulases can also be co-expressed in host cells with other cellulases. The expression in such host cells of the termite and termite-associated symbiont cellulases, and variants and combinations thereof, result in yeast with improved cellulosic activity. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.Type: ApplicationFiled: February 24, 2014Publication date: January 22, 2015Applicant: Mascoma CorporationInventors: Elena E. Brevnova, Vineet Rajgarhia, Mark Mellon, Anne Warner, John McBride, Chhayal Gandhi, Erin Wiswall
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Publication number: 20140308724Abstract: The present invention is directed to a yeast strain, or strains, secreting a full suite, or any subset of that full suite, of enzymes to hydrolyze corn starch, corn fiber, lignocellulose, (including enzymes that hydrolyze linkages in cellulose, hemicellulose, and between lignin and carbohydrates) and to utilize pentose sugars (xylose and arabinose). The invention is also directed to the set of proteins that are well expressed in yeast for each category of enzymatic activity. The resulting strain, or strains can be used to hydrolyze starch and cellulose simultaneously. The resulting strain, or strains can be also metabolically engineered to produce less glycerol and uptake acetate. The resulting strain, or strains can also be used to produce ethanol from granular starch without liquefaction.Type: ApplicationFiled: February 12, 2014Publication date: October 16, 2014Applicants: Stellenbosch University, Mascoma CorporationInventors: Elena BREVNOVA, John E. McBride, Erin Wiswall, Kevin S. Wenger, Nicky Caiazza, Heidi Hau, Aaron Argyros, Frank Agbogbo, Charles F. Rice, Trisha Barrett, John S. Bardsley, Abigail Foster, Anne K. Warner, Mark Mellon, Ryan Skinner, Indraneel Shikhare, Riaan Den Haan, Chhayal V. Gandhi, Alan Belcher, Vineet B. Rajgarhia, Allan C. Froehlich, Kristen M. Deleault, Emily Stonehouse, Shital A. Tripathi, Jennifer Gosselin, Yin-Ying Chiu, Haowen Xu
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Patent number: 8658398Abstract: The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be codon-optimized and expressed in yeast host cells, such as the yeast Saccharomyces cerevisiae. The cellulases can also be co-expressed in host cells with other cellulases. The expression in such host cells of the termite and termite-associated symbiont cellulases, and variants and combinations thereof, result in yeast with improved cellulosic activity. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.Type: GrantFiled: July 7, 2009Date of Patent: February 25, 2014Assignee: Mascoma CorporationInventors: Elena E. Brevnova, Vineet Rajgarhia, Mark Mellon, Anne Warner, John McBride, Chhayal Gandhi, Erin Wiswall
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Publication number: 20130323822Abstract: The present invention is directed to a yeast strain, or strains, secreting a full suite, or any subset of that full suite, of enzymes to hydrolyze corn starch, corn fiber, lignocellulose, (including enzymes that hydrolyze linkages in cellulose, hemicellulose, and between lignin and carbohydrates) and to utilize pentose sugars (xylose and arabinose). The invention is also directed to the set of proteins that are well expressed in yeast for each category of enzymatic activity. The resulting strain, or strains can be used to hydrolyze starch and cellulose simultaneously. The resulting strain, or strains can be also metabolically engineered to produce less glycerol and uptake acetate. The resulting strain, or strains can also be used to produce ethanol from granular starch without liquefaction.Type: ApplicationFiled: June 3, 2011Publication date: December 5, 2013Applicant: Mascoma CorporationInventors: Elena Brevnova, John E. McBride, Erin Wiswall, Kevin S. Wenger, Nicky Caiazza, Heidi Hau, Aaron Argyros, Frank Agbogbo, Charles F. Rice, Trisha Barrett, John S. Bardsley, Abigail S. Foster, Anne K. Warner, Mark Mellon, Ryan Skinner, Indraneel Shikhare, Riaan Den Haan, Chhayal V. Gandhi, Alan Belcher, Vineet B. Rajgarhia, Allan C. Froehlich, Kristen M. Deleault, Emily Stonehouse, Shital A. Tripathi, Jennifer Gosselin, Yin-Ying Chiu, Haowen Xu
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Publication number: 20120158153Abstract: A trapezium prosthesis is provided which includes a body having a frustocylindrical shape, the frustocylindrical shape including a frustum and an oppositely disposed planar base, the frustum being canted relative to a planar base. The prosthesis may be made of a swellable fluid absorbing polymer which imparts flexibility and/or resiliency to the prosthesis. The swellable fluid absorbing polymer may also provide the surface of the prosthesis with lubricity. In embodiments, the prosthesis has a first configuration and a second configuration, the first configuration being of reduced size relative to the second configuration. The prosthesis may also include a reinforcement member. In embodiments, the prosthesis includes a stem projecting outwardly from the frustum.Type: ApplicationFiled: June 23, 2010Publication date: June 21, 2012Applicant: REPLICATION MEDICAL INC.Inventors: Frederick H. Hardenbrook, Seth D. Dodds, Mark Mellon
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Publication number: 20120142046Abstract: The present invention relates to the engineering and expression of heterologous cellulosomes in microorganisms in order to facilitate the conversion of biomass to useful products. In some embodiments, the invention relates to the expression of scaffoldin proteins which form the nucleus of a cellulosome. Cellulases or other biomass-degrading enzymes can be non-covalently linked to the scaffoldin protein by virtue of a dockerin domain-cohesin domain interaction.Type: ApplicationFiled: February 18, 2010Publication date: June 7, 2012Inventors: John McBride, Mark Mellon, Vineet Rajgarhia, Elena E. Brevnova, Erin Wiswall, David A. Hogsett, Danie LaGrange, Shaunita Rose, Emile Van Zyl
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Publication number: 20120129229Abstract: Host cells, comprising Kluveryomyces expressing heterologous cellulases produce ethanol from cellulose In addition, multiple host cells expressing different heterlogous cellulases can be co-cultured together and used to produce ethanol from cellulose The recombinant yeast strains and co-cultures of the yeast strains can be used to produce ethanol on their own, or can also be used in combination with externally added cellulases to increase the efficiency of sacchanfication and fermentation processesType: ApplicationFiled: November 23, 2009Publication date: May 24, 2012Inventors: John McBride, Elena Brevnova, Mark Mellon, Allan Froehlich, Kristen Deleault, Vineet Rajgarhia, Riaan Den Haan, Merja Penttila, Marja Ilmen, Matti Siika-Aho, Jaana Uusitalo, Emily A. Stonehouse, Alan Gilbert, Haowen Xu, Deidre Willes, John Bardsley, Anu Koivula, Sanni Voutilainen
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Publication number: 20120003701Abstract: The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be codon-optimized and expressed in yeast host cells, such as the yeast Saccharomyces cerevisiae. The cellulases can also be co-expressed in host cells with other cellulases. The expression in such host cells of the termite and termite-associated symbiont cellulases, and variants and combinations thereof, result in yeast with improved cellulosic activity. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.Type: ApplicationFiled: July 7, 2009Publication date: January 5, 2012Applicant: MASCOMA CORPORATIONInventors: Elena E. Brevnova, Vineet Rajgarhia, Mark Mellon, Anne Warner, John Mcbride, Chhayal Gandhi, Erin Wiswall
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Patent number: 6390299Abstract: This invention relates to carrier straps for carrying prepared foods, such as rotisserie chickens, roasted turkey, roasted ham, side dishes or deserts. Such structures of this type, generally, employ a one-handed, paperboard strap which is wrapped around the plastic tray and plastic domed lid package in which the prepared food is located. The carrier strap secures the prepared food package and transports it so that the purchaser's hands do not get greasy or hot. Also, the carrier strap functions to provide a printable surface to identify flavor and brand.Type: GrantFiled: January 29, 2001Date of Patent: May 21, 2002Assignee: Westvaco Corp.Inventors: Mark Mellon, William Roger Rigby
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Patent number: 6249916Abstract: A garment having a cuff construction with an opening for permitting the thumb of the wearer and the fingers to extend outside the sleeve. The cuff is generally integrally attached to an article of clothing, and folds in on itself for storing the cuff permitting the use or non use of the cuff at the user's direction. The cuff is formed at an opening of a sleeve in a garment, and includes a tubular member which is switchable between a first rolled position allowing the hand to pass through and a second unrolled position forming a covering around at least a portion of the hand and/or thumb while leaving the ends of the fingers and thumb exposed.Type: GrantFiled: March 9, 2000Date of Patent: June 26, 2001Assignee: Handcuffs, Inc.Inventors: Charles B. Mellon, Mark A. Mellon
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Patent number: 6089416Abstract: This invention relates to packages which are designed to dispense a pre-determined amount of product. Such structures of this type, generally, include a series of internal folds that allow a pre-determined amount of product to be loaded into the dispensing chamber. This pre-determined amount is then dispersed from the dispensing chamber by the end-user until the chamber is empty.Type: GrantFiled: February 1, 1999Date of Patent: July 18, 2000Assignee: Westvaco CorporationInventor: Mark Mellon
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Patent number: 6047829Abstract: This invention relates to a two piece paperboard package that houses a unit dose product on an internal slide card within an outer paperboard shell. This package may have one or more internal or external lock(s) that prevent the slide card from being pulled out without triggering some type of lock release mechanism. This package is focused around providing a child resistant, senior-friendly unit dose package that can be opened and closed numerous times and then finally disposed of.Type: GrantFiled: September 18, 1998Date of Patent: April 11, 2000Assignee: Westvaco CorporationInventors: Scott Bowen Johnstone, Brad Allen Jones, Mark Mellon, William Roger Rigby
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Patent number: 6035441Abstract: A garment having a cuff construction with an opening for permitting the thumb of the wearer and the fingers to extend outside the sleeve. The cuff is generally integrally attached to an article of clothing, and folds in on itself for storing the cuff permitting the use or non use of the cuff at the user's direction. The cuff is formed at an opening of a sleeve in a garment, and includes a tubular member which is switchable between a first rolled position allowing the hand to pass through and a second unrolled position forming a covering around at least a portion of the hand and/or thumb while leaving the ends of the fingers and thumb exposed.Type: GrantFiled: July 24, 1998Date of Patent: March 14, 2000Inventors: Charles B. Mellon, Mark A. Mellon
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Patent number: 5954202Abstract: This invention relates to paperboard blanks which are used to form self-contained, reclosable packages. Such structures of this type, generally, are comprised of one piece of paperboard that when folded acts as an outer package when sealed and an innovative reclosable package after being opened.Type: GrantFiled: March 4, 1998Date of Patent: September 21, 1999Assignee: Westvaco CorporationInventor: Mark Mellon
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Patent number: 5927595Abstract: A multi-use envelope for at least two mailings comprises opposed front and rear panels foldably connected together at their bottom edges and secured together at their side edges by side closure flaps to form an envelope structure. The improvement comprises a pair of closure flaps foldably attached respectively to the top edges of each of the front and rear panels wherein each closure flap has an independent means for sealing and opening the envelope. A first closure flap is folded inside the envelope for the first mailing while the other closure flap is used to close the envelope. Upon receipt, the first closure flap is folded outside the envelope for use in closing the envelope for the second mailing.Type: GrantFiled: July 20, 1998Date of Patent: July 27, 1999Assignee: Westvaco CorporationInventors: Mark Mellon, William R. Rigby, Arthur J. Thomas
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Patent number: 5784720Abstract: A garment having a cuff construction with an opening for permitting the thumb of the wearer and the fingers to extend outside the sleeve. The cuff is generally integrally attached to an article of clothing, and folds in on itself for storing the cuff permitting the use or non use of the cuff at the user's direction. The cuff is formed at an opening of a sleeve in a garment, and includes a tubular member which is switchable between a first rolled position allowing the hand to pass through and a second unrolled position forming a covering around at least a portion of the hand and/or thumb while leaving the ends of the fingers and thumb exposed.Type: GrantFiled: July 3, 1997Date of Patent: July 28, 1998Assignee: Handcuffs, Inc.Inventors: Charles B. Mellon, Mark A. Mellon
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Patent number: 5626283Abstract: A combination container for food and condiments is formed from a one piece blank of paperboard material. The finished container includes a first compartment in the shape of a scoop for holding the food product and a second compartment in the form of a pouch which can be extended outwardly from the first compartment for condiments. The second compartment is collapsed against one wall of the first compartment when not in use for easy stacking of the containers.Type: GrantFiled: February 7, 1996Date of Patent: May 6, 1997Assignee: Westvaco CorporationInventor: Mark Mellon
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Patent number: D462904Type: GrantFiled: June 25, 2001Date of Patent: September 17, 2002Assignee: Westvaco CorporationInventors: Mark Mellon, William Roger Rigby