Abstract: A method of determining a personalised therapeutic regime, comprising: receiving genetic information relating to a patient; determining genetic criteria relevant to a personalised therapeutic regime for the patient using the genetic information; receiving personal information relating to the patient; determining personal criteria relevant to the personalised therapeutic regime using the personal information; and combining the genetic criteria and the personal criteria to determine the personalised therapeutic regime for the patient.

Abstract: A one stage process for the preparation reservoir patches comprises feeding webs to a first pair of sealing rollers and, thence, directly to a second pair of die-cutting rollers, and in certain embodiments, directly into a packaging step, thereby avoiding most operator-related error, and substantially increasing overall sterility and reproducibility

Abstract: A beverage container for the storage of a carbonated drink comprising a container body (10) including an opening (11) and removable closure means (12) for closing the opening (11), the closure means comprising a foil (20) which provides a gas tight seal for the opening (11). The arrangement may be such that a tendency of forces acting on the foil (20) due to pressure within the container to separate the foil (20) from the container body (10) by peeling away therefrom is reduced e.g. by the provision of a collar (12A) to limit deflection of the foil (20) adjacent the bond therebetween and/or by the shape of the rim (15) of the container body (10), so the closure is capable of withstanding higher internal pressures than would otherwise be the case.

Abstract: A continuous process for forming a transdermal patch which comprises the steps of: continuously feeding a strip of material comprising a layer of permeable membrane; continuously feeding into close proximity and in face-to-face relationship with the first strip a second strip formed of impermeable backing material; passing the first and second strips together through a filling and sealing station in which the material containing an active substance is introduced between the strips and pouches are formed by first sealing devices which seal the strips together in a longitudinal direction of the strips and second sealing devices which seal the strips together in a transverse direction of the strips; the size of the pouches being adjusted by adjusting the number position and/or frequency of operation of the first sealing devices and/or by adjusting the number position and/or frequency of operation of the second sealing devices.

Abstract: A system to mix, carbonate, if desired, and dispense beverages in the micro-gravity environment of extra-terrestrial space incorporates chilled sources of beverage syrup, water and CO.sub.2, mixing chambers for receiving the fluid components of the beverages and receptacle interfaces which. selectively communicate with the mixing chambers and which couple with drinking receptacles formed by a pressure-resistant outer shell and a flexible internal liner. Within the mixing chambers, a reciprocable piston is driven by an entering pressurized beverage component to a retracted position and is subsequently driven by compressed air to an extended position with a concurrent expulsion of the mixed beverage from the mixing chamber and into the liner of a drinking receptacle coupled to one of the receptacle interfaces. A formation on the piston reacts with an agitator to enhance mixing of the beverage components.