Abstract: Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible TNF receptor (GITR). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.

Abstract: Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of fabricating, deploying, inflating, locating, tracking, monitoring, deflating, and retrieving the same are provided.

Abstract: A consensus protocol-based replication approach is provided. Chunks are grouped into replication units (RUs) to optimize replication efficiency. Chunks may be assigned to RUs based on load and replication throughput. Splitting and merging RUs do not interrupt concurrent user workload or require routing changes. Transactions spanning chunks within an RU do not require distributed transaction processing. Each replication unit has a replication factor (RF), which refers to the number of copies/replicas of the replication unit, and an associated distribution factor (DF), which refers to the number of servers taking over the workload from a failed leader server. RUs may be placed in rings of servers, where the number of servers in a ring is equal to the replication factor, and quiescing the workload can be restricted to a ring of servers instead of the entire database.

Abstract: A lead-sync log record is used to synchronize the replication logs of follower shards to the leader shard. In response to a failure to determine that there is a consensus for a database transaction commit operation after a shard server becomes a new leader, the new leader shard performs a sync operation using the lead-sync log record to synchronize replication logs of the follower shards to the replication log of the new leader. A shard server identifies a first transaction having a first log record but not a post-commit log record in the replication log, defines a recovery window in the replication log starting at the first log record of the identified first transaction and ending at the lead-sync log record, identifies a set of transactions to be recovered, and performs a recovery action on the set of transactions to be recovered.

Abstract: A consensus protocol-based replication approach is provided. For each change operation performed by a leader server on a copy of the database, the leader server creates a replication log record and returns a result to the client. The leader does not wait for consensus for the change operation from the followers. For a commit, the leader creates a commit log record and waits for consensus. Thus, the leader executes database transactions asynchronously, performs replication of change operations asynchronously, and performs replication of transaction commits synchronously.

Abstract: A visualization system comprising a persistent memory, storing a dataset, and a non-persistent memory implements a pattern visualizing method. The dataset contains discrete attribute values for each first entity of a first type in a plurality of first entities of the first type and discrete attribute values for each first entity of a second type in a plurality of first entities of the second type for each second entity in a plurality of second entities. The dataset is compressed by blocked compression and represents discrete attribute values in both compressed sparse row and column formats. The discrete attribute values are clustered to assign each second entity to a cluster in a plurality of clusters.

Abstract: Polymeric nanoparticles comprising a defined set of biologically active agents that provide for targeted stimulation of non-responsive T cells, e.g. T cells involved in cancer, are provided.

Abstract: A system (200) for conducting a vision assessment test of an eye of a patient comprising: a display screen (201) for displaying at least one test profile to the patient; an eye tracker controlled for detecting a gaze direction data of the eye of the patient when viewing the test profile(s); and a processor for processing the detected gaze direction data and identifying a correlation between the gaze direction data and the test profile(s) to thereby obtain a vision assessment of the patients eye; wherein the system comprises a user interface (203) for enabling an operator of the system to author the test profile(s) for the patient by controlling one or more parameters of the test profile(s) prior to the vision assessment test being conducted.

Abstract: A visualizer receives a compiled program to be run on a tensor streaming processor, which indicates a predetermined timing at which each functional unit of the processor receives instructions for processing data, and generates a visualization model used to display a schedule comprising elements corresponding to instructions received by each functional unit of a data path of the processor, arranged based upon a time at which each instruction is executed by its respective functional unit in accordance with the generated model. Due to the deterministic nature of the tensor streaming processor, the visualizer infers the flow of data across communication lanes of the processor, and to predicts the location of data within the processor for a given cycle during execution of the compiled program, without the need to actually execute the compiled program or to implement breakpoints within the program at specific cycles.

Abstract: Provided herein is a portable clothes drying device, which includes a base unit and an air outlet unit; wherein the base unit is configured to not only enable the portable clothes drying device to be used in various kinds of use spaces, but also provide the portable clothes drying device with the functions of heating, drying, disinfecting, etc.; and wherein the air outlet unit is configured to correspond to various kinds of clothes with different geometric shapes.

Abstract: An apparatus and a method for synchronizing output clock signals across a plurality of phase-locked loops (PLLs). The apparatus coupled within each PLL comprises: a local counter configured to provide a count when receiving a reference clock signal; a comparator configured to compare the count from the local counter with a predetermined or preconfigured value; wherein a multiplexor connected to the local counter and counters of adjacent PLLs, configured to select the count from the local counter or a count from the counters of the adjacent PLLs; wherein the selected count from the multiplexor is incremented and directed to the local counter; wherein an output clock divider enable is asserted to the PLL to start an output clock divider to generate the output clock signal when the count from the local counter reaches the predetermined or preconfigured value.

Abstract: A stent delivery system for dynamic deployment of a stent loaded thereon and a method of manufacturing the system. The stent delivery system includes a balloon catheter with a balloon in a spirally twisted delivery configuration on which a stent is crimped or otherwise loaded. The stent is made from a single, continuous strand of wire formed into a sinusoidal waveform that is wrapped into a helical pattern and joined at selected crowns. Upon inflation of the spirally twisted balloon of the stent delivery system, the stent undergoes dynamic deployment such that the stent in a deployed or expanded configuration has crowns with obtuse deployment angles and crowns with acute deployment angles.

Abstract: A baseball fielding glove capable of receiving a human hand is provided. The glove comprises an exterior glove shell and an interior glove liner. The glove comprises a strut in place of traditional webbing. Further, the glove's exterior shell corresponding to the palm of a wearer comprises a plurality of perforations for enhancing ventilation. The fielding glove disclosed is readily adjustable eliminating the need for a breaking-in process. A tensioning cord extending between the strut and finger/thumb stalls of the glove provide an enhanced degree of adjustable characteristics to the glove.

Abstract: A stent delivery system for dynamic deployment of a stent loaded thereon and a method of manufacturing the system. The stent delivery system includes a balloon catheter with a balloon in a spirally twisted delivery configuration on which a stent is crimped or otherwise loaded. The stent is made from a single, continuous strand of wire formed into a sinusoidal waveform that is wrapped into a helical pattern and joined at selected crowns. Upon inflation of the spirally twisted balloon of the stent delivery system, the stent undergoes dynamic deployment such that the stent in a deployed or expanded configuration has crowns with obtuse deployment angles and crowns with acute deployment angles.

Abstract: A baseball fielding glove capable of receiving a human hand is provided. The glove comprises an exterior glove shell and an interior glove liner. The glove comprises a strut in place of traditional webbing. Further, the glove's exterior shell corresponding to the palm of a wearer comprises a plurality of perforations for enhancing ventilation. The fielding glove disclosed is readily adjustable eliminating the need for a breaking-in process. A tensioning cord extending between the strut and finger/thumb stalls of the glove provide an enhanced degree of adjustable characteristics to the glove.

Abstract: The present invention is a lawn mower powered by a compression ignition combustion engine that can utilize multiple fuel types such as petroleum based fuels or plant based fuels or any combination thereof. The lawn mower includes a chassis with a rear end having a plurality of spaced wheels, a compression ignition engine mounted on the chassis to provide power to the lawn mower and one or more grass cutting blades mounted directly or indirectly on an output shaft of the compression ignition engine. The lawn mower also includes a handle projecting from the rear end of chassis and a fuel tank, a fuel line, a fuel pump and a fuel injector to provide the multiple fuel types to the compression ignition engine.

Abstract: Aggregation of product data provided from external sources of product data for presentation on an e-commerce website. A set of product data related to a product that is offered for sale in e-commerce is accessed and subjected to an aggregation process. The set of product data is mapped for aggregation with other sets of product data based on an existing mapping or on an absence of an existing mapping. Access is provided to an aggregated set of product data that includes the set of product data that is mapped for aggregation with other sets of product data, for presentation on an e-commerce website.

Abstract: The present invention is a lawn mower with a compression ignition combustion engine that can use multiple fuel types such as petroleum based fuels or plant based fuels or any combination thereof. The lawn mower includes a chassis with a rear end having a plurality of spaced wheels, a compression ignited engine mounted on the chassis to provide power to the lawn mower and a plurality of grass cutting blades mounted directly or indirectly on an output shaft of the compression ignited engine. The lawn mower also includes a handle projecting from the rear end of chassis and a fuel tank and a fuel line supported by the chassis to provide the multiple fuel types to the compression ignited engine.

Abstract: A device can include a detection module and a correction module. The detection module can classify a pixel in a sensor as a defective pixel, and can store location information for the defective pixel. The correction module can identify the defective pixel based on the location information, and can correct a digital pixel signal corresponding to the defective pixel.