Abstract: The present invention is directed to a new fluoro-pyridinone hydroxamic acid phosphates and boronates of Formulae I, II and III wherein Q is selected from the group consisting of —P(O)(OH)2, —P(O)(OH)(O?M+), —P(O)(O?M+)2 and —P(O)(O?)2M2+; M+ at each occurrence is a pharmaceutically acceptable monovalent cation; and M2+ is a pharmaceutically acceptable divalent cation and their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: A golf club head having a flexible channel to improve the performance of the club head, and a channel tuning system to reduce undesirable club head characteristics introduced, or heightened, via the flexible channel. The channel tuning system includes a sole engaging channel tuning element in contact with the sole and the channel. The club head may include an aerodynamic configuration, as well as a body tuning system.

Abstract: The present disclosure is related to techniques for converting a natural language utterance to a logical form query and deriving a natural language interpretation of the logical form query. The techniques include accessing a Meaning Resource Language (MRL) query and converting the MRL query into a MRL structure including logical form statements. The converting includes extracting operations and associated attributes from the MRL query and generating the logical form statements from the operations and associated attributes. The techniques further include translating each of the logical form statements into a natural language expression based on a grammar data structure that includes a set of rules for translating logical form statements into corresponding natural language expressions, combining the natural language expressions into a single natural language expression, and providing the single natural language expression as an interpretation of the natural language utterance.

Abstract: A multi-functional sensor assembly includes an electrically non-conductive substrate defining at least a distal region, intermediary region, and proximal region that are each covered with electrically conductive traces. The proximal region is configured to be exposed to a media to be sensed and the distal and intermediary regions are configured to be protected from the media. The electrically conductive traces comprise at least electrical circuits to sense temperature and flow of the media and one or more electrodes to sense one or more of conductivity, oxidation reduction potential (ORP), and acidity (pH) of the media.

Abstract: A series of fused pentacyclic imidazole derivatives, being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders. In particular, the present invention is concerned with 6, 7-dihydro-7, 14-methanobenzimidazo[1, 2-b][2,5]benzodiazocin-5(14H)-one derivatives and analogs thereof.

Abstract: Methods and systems for implementing a Jupiter aerospace mission can enable delivery of a science payload to a Jupiter orbit on a direct Earth-to-Jupiter trajectory. Solar power and use of avionics also allow a fast assembly, integration, and test process compared to past outer Solar System missions. The spacecraft can include an aerodynamic forebody, a shell, and a thermal protection system. The spacecraft can manage the radiation environment, generate solar power, and return data to Earth with a robust radio-frequency (RF) amplification and antenna gain.

Abstract: A compressor comprising: a stator assembly comprising a plurality of stator elements; a rotor assembly comprising a shaft to which is mounted at least one bearing, a permanent magnet and an impeller; a support body; and an outer can comprising an air inlet. The support body comprises a hollow elongate central part to which is mounted the at least one bearing, and inside which the magnet is positioned, the elongate central part comprising a plurality of openings, and the air inlet of the outer can is axially aligned at least partially with the plurality of openings in the elongate central part.

Abstract: A brushless motor comprising a rotor assembly comprising a shaft, an impeller, a bearing assembly and a rotor core; a stator assembly; a frame comprising an outer portion and a support portion radially inward of the outer portion, the support portion supporting at least one of the rotor assembly and the stator assembly; and at least one strut extending between the outer portion and the support portion, wherein the strut and the stator assembly are aligned such that at least part of the strut and at least part of the stator assembly are disposed along a line substantially parallel to a rotation axis of the rotor assembly.

Abstract: A compressor has a rotor assembly having an impeller for generating an airflow through the compressor, a stator core assembly for causing rotation of the impeller, and a diffuser assembly for acting on the airflow generated by the impeller. The diffuser assembly has a first diffuser stage and a second diffuser stage. The first and second diffuser stages are separate components connected to one another by a fastener.

Abstract: An apparatus for monitoring the condition of a pneumatic tyre including a pressure sensor(s) to measure an internal pressure within the tyre. A speed sensor(s) measures a rotational speed of the tyre. A controller is configured to receive data from the pressure sensor and the speed sensor and output indications related to a condition of the tyre. The controller determines the output indications by tracking the internal pressure with respect to time during use of the tyre, identifying at least one change in internal tyre pressure in a time interval. The time interval is between a first reference time and a second reference time, the reference times corresponding to points at which the speed sensor indicates different rotational speeds of the tyre. The controller further monitors the pressure change as a function of rotational speed of the tyre to provide an indicator of tyre condition.

Abstract: Systems and methods for implementing model-based application control frameworks are disclosed. In one embodiment, in an information processing apparatus comprising at least one computer processor, a method for implementing model-based application control frameworks may include: (1) breaking an application into a plurality of modules, wherein each module comprises a component of the application that is capable of running independently; (2) determining a plurality of attributes for each of the modules; (3) identifying a deployment platform for each module; (4) building an attribute model for the application based on the modules, the attributes, and the deployment platform; (5) identifying control requirements for the attribute model; (6) identifying actions to implement the control requirements; and (7) deploying the actions to implement the control requirements to the application.

Abstract: A compressor has a rotor assembly having an impeller for generating an airflow through the compressor, a stator core assembly for causing rotation of the impeller, and a diffuser assembly for acting on the airflow generated by the impeller. The diffuser assembly has a first diffuser stage and a second diffuser stage. The first and second diffuser stages are separate components connected to one another by a fastener.

Abstract: Systems and methods for implementing model-based application control frameworks are disclosed. In one embodiment, in an information processing apparatus comprising at least one computer processor, a method for implementing model-based application control frameworks may include: (1) breaking an application into a plurality of modules, wherein each module comprises a component of the application that is capable of running independently; (2) determining a plurality of attributes for each of the modules; (3) identifying a deployment platform for each module; (4) building an attribute model for the application based on the modules, the attributes, and the deployment platform; (5) identifying control requirements for the attribute model; (6) identifying actions to implement the control requirements; and (7) deploying the actions to implement the control requirements to the application.

Abstract: A compressor blade having a leading edge and a trailing edge, and a surface pattern between the leading and trailing edges, the surface pattern comprising at least one set of herringbone riblets formed of a plurality of v-shaped riblets, wherein the v-shaped riblets are spaced apart by a distance of between 200-400 ?m, and have a height of between 50-120 ?m.

Abstract: A vacuum cleaner having a main body and a dirt separator that is removably attached to the main body. The dirt separator includes a first dirt-separation stage, a second dirt-separation stage, and a vacuum motor for moving air through the first dirt-separation stage and the second dirt-separation stage. The vacuum motor has an impeller driven by an electric motor. The first dirt-separation stage is then located upstream of the impeller, and the second dirt-separation stage is located downstream of the impeller.

Abstract: A brushless motor comprising a rotor assembly comprising a shaft, an impeller, a bearing assembly and a rotor core; a stator assembly; a frame comprising an outer portion and a support portion radially inward of the outer portion, the support portion supporting at least one of the rotor assembly and the stator assembly; and at least one strut extending between the outer portion and the support portion, wherein the strut and the stator assembly are aligned such that at least part of the strut and at least part of the stator assembly are disposed along a line substantially parallel to a rotation axis of the rotor assembly.

Abstract: A compressor comprising: a stator assembly comprising a plurality of stator elements; a rotor assembly comprising a shaft to which is mounted at least one bearing, a permanent magnet and an impeller; a support body; and an outer can comprising an air inlet. The support body comprises a hollow elongate central part to which is mounted the at least one bearing, and inside which the magnet is positioned, the elongate central part comprising a plurality of openings, and the air inlet of the outer can is axially aligned at least partially with the plurality of openings in the elongate central part.

Abstract: A vacuum cleaner having a dirt-separation stage and a vacuum motor for moving air through the dirt-separation stage. The vacuum motor includes an impeller driven by an electric motor. The impeller is then located upstream of the dirt-separation stage, the electric motor is located downstream of the dirt-separation stage, and at least part of the air discharged from the dirt-separation stage is used to cool the electric motor.

Abstract: A vacuum cleaner that includes a first dirt-separation stage, a second dirt-separation stage, and a vacuum motor for moving air through the first dirt-separation stage and the second dirt-separation stage. The vacuum motor has a centrifugal impeller driven by an electric motor. The first dirt-separation stage is then located upstream of the impeller, the second dirt-separation stage is located downstream of the impeller, and the second dirt-separation stage has a plurality of cyclonic separators that are arranged around the vacuum motor.

Abstract: A vacuum cleaner that includes a first dirt-separation stage, a second dirt-separation stage, and a vacuum motor for moving air through the first dirt-separation stage and the second dirt-separation stage. The vacuum motor has a centrifugal impeller driven by an electric motor. The first dirt-separation stage is then located upstream of the impeller, the second dirt-separation stage is located downstream of the impeller, and the second dirt-separation stage has a plurality of cyclonic separators that are arranged around the vacuum motor.