Abstract: The present application provides a method of treating a condition associated with coronavirus infection, the condition selected from acute respiratory distress, lung inflammation, systemic inflammation, or cytokine storm, the method comprising administration of furosemide or a pharmaceutically acceptable salt or hydrate thereof.

Abstract: The present application provides terpene analogues of Formula 1 and methods and uses thereof for treating neurological conditions such as pain in general and neuropathic pain specifically. wherein: Y is a C1 to C20 alkylene, C?O, SO, SO2, or absent; X is H, OR1, N—(R2)2, a C1 to C20 alkyl, or a heterocyclyl (for example, heteroaryl), wherein when Y is absent X is not H; R1 is H, a C1 to C20 alkyl, or a CH2-aryl; R2 is independently H, a C1 to C20 alkyl, aryl, OR1, CN or C(?O)—R3; R3 is a substituted or unsubstituted C1 to C20 alkyl, or a aryl; W is H, C1 to C20 alkyl, or aryl; and Z is C1 to C20 alkylene; or a pharmaceutically acceptable isomer, salt or ester thereof. These terpene analogues are useful in treating pain and can also be used to treat other electrical disorders in the central and peripheral nervous system.