Patents by Inventor MARK B. TAUBMAN

MARK B. TAUBMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of pulmonary hypertension using an agent that inhibits a tissue factor pathway
    Patent number: 8563511
    Abstract: An improved non-human animal model of severe pulmonary arterial hypertension (PAH) and its use for testing of therapeutic agents that can treat symptoms of PAH are disclosed. In addition, the present application relates to the identification of several classes of therapeutic agents that, alone or in combination, can be used to treat or prevent PAH or at least reduce the severity of symptoms associated therewith. Both gene therapy and non-gene therapy approaches are described.
    Type: Grant
    Filed: October 6, 2005
    Date of Patent: October 22, 2013
    Assignee: University of Rochester
    Inventors: R. James White, Mark B. Taubman
  • Treatment of Pulmonary Hypertension Using an Agent That Inhibits a Tissue Factor Pathway
    Publication number: 20080267969
    Abstract: An improved non-human animal model of severe pulmonary arterial hypertension (PAH) and its use for testing of therapeutic agents that can treat symptoms of PAH are disclosed. In addition, the present application relates to the identification of several classes of therapeutic agents that, alone or in combination, can be used to treat or prevent PAH or at least reduce the severity of symptoms associated therewith. Both gene therapy and non-gene therapy approaches are described.
    Type: Application
    Filed: October 6, 2005
    Publication date: October 30, 2008
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: R. James White, Mark B. Taubman
  • Vascular endothelial zinc finger 1 gene and protein and uses thereof
    Publication number: 20030167479
    Abstract: The present invention relates to the diagnosis and treatment of vascular disorders, and to assays for the identification of agents which act upon the circulatory system. It is based, at least in part, on the identification of a novel mouse gene, termed Vezf1 (for “Vascular endothelial zinc finger 1”), which is expressed at higher levels during embryonic development of the circulatory system, in damaged blood vessels, and in newly formed blood vessels associated with tumor growth.
    Type: Application
    Filed: January 17, 2002
    Publication date: September 4, 2003
    Applicant: Mount Sinai School of Medicine of the City University of New York
    Inventors: Heidi Stuhlmann, Jing-Wei Xiong, Mark B. Taubman
  • Vascular endothelial zinc finger 1 gene and protein and uses thereof
    Publication number: 20020023277
    Abstract: The present invention relates to the diagnosis and treatment of vascular disorders, and to assays for the identification of agents which act upon the circulatory system. It is based, at least in part, on the identification of a novel mouse gene, termed Vezf1 (for “Vascular endothelial zinc finger 1”), which is expressed at higher levels during embryonic development of the circulatory system, in damaged blood vessels, and in newly formed blood vessels associated with tumor growth.
    Type: Application
    Filed: May 22, 1998
    Publication date: February 21, 2002
    Inventors: HEIDI STUHLMANN, JING-WEI XIONG, MARK B. TAUBMAN