Patents by Inventor Mark D. Williams
Mark D. Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240158398Abstract: Described herein are compounds that inhibit ALK2 and its mutants, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.Type: ApplicationFiled: April 20, 2023Publication date: May 16, 2024Inventors: Natasja Brooijmans, Jason D. Brubaker, Paul E. Fleming, Brian Lewis Hodous, Joseph L. Kim, Brett D. Williams, Douglas Wilson, Kevin J. Wilson, Mark Cronin
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Publication number: 20240151173Abstract: An exhaust gas heater system for an exhaust system of an internal combustion engine includes a housing and a heating element. The housing includes an outer peripheral wall disposed about a central axis and defining an interior hollow space configured to receive exhaust gas from an exhaust pipe of the exhaust system such that the exhaust gas flows through the interior hollow space. The heating element is positioned within the hollow space and including a first end and a second end. The heating element forms a zig-zag shape extending in a radial direction relative to the central axis.Type: ApplicationFiled: January 19, 2024Publication date: May 9, 2024Applicant: WATLOW ELECTRIC MANUFACTURING COMPANYInventors: Mark D. EVERLY, Jeremy OHSE, David P. CULBERTSON, Richard T. WILLIAMS, George JAMBOR, Jacob WILSON
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Patent number: 11969300Abstract: An implantable medical lead may include an electrode at a distal portion of the lead that is configured to monitor or provide therapy to a target site. The lead may include a visible indicator that is visible to the naked eye of a clinician at a medial portion of the lead that is configured to indicate when the electrodes of the lead are longitudinally and radially aligned properly to monitor or treat the target site. A clinician may insert the lead into the patient using an introducer sheath inserted to a predetermined depth into the patient and subsequently aligning the distal portion of the lead by orienting the indicator at an entry port of the introducer sheath.Type: GrantFiled: August 12, 2021Date of Patent: April 30, 2024Assignee: Medtronic, Inc.Inventors: George W. McFall, Thomas D. Brostrom, Mark T. Marshall, Dina L. Williams, Megan Harris, Keith D. Anderson, Maggie J. Pistella
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Patent number: 11913365Abstract: An exhaust gas heater system for an exhaust system of an internal combustion engine includes a housing and a heating element. The housing includes an outer peripheral wall disposed about a central axis and defining an interior hollow space configured to receive exhaust gas from an exhaust pipe of the exhaust system such that the exhaust gas flows through the interior hollow space. The heating element is positioned within the hollow space and including a first end and a second end. The heating element forms a zig-zag shape extending in a radial direction relative to the central axis.Type: GrantFiled: July 26, 2022Date of Patent: February 27, 2024Assignee: WATLOW ELECTRIC MANUFACTURING COMPANYInventors: Mark D. Everly, Jeremy Ohse, David P. Culbertson, Richard T. Williams, George Jambor, Jacob Wilson
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Publication number: 20230243256Abstract: Systems and methods corresponding with improved wellfield management are provided. In some examples, the system may initiate a step drawdown test of well efficiency to determine a cause of a decreased discharge rate of the wellfield site. The system may alter pumping of the wellfield site based on the step drawdown test, wherein a command signal is transmitted via a SCADA system to the wellfield site.Type: ApplicationFiled: April 6, 2023Publication date: August 3, 2023Applicant: GEOSCIENCE Support Services, Inc.Inventors: Dennis E. Williams, Mark D. Williams
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Patent number: 11624278Abstract: Systems and methods corresponding with improved wellfield management are provided. In some examples, the system may initiate a step drawdown test of well efficiency to determine a cause of a decreased discharge rate of the wellfield site. The system may alter pumping of the wellfield site based on the step drawdown test, wherein a command signal is transmitted via a SCADA system to the wellfield site.Type: GrantFiled: May 8, 2020Date of Patent: April 11, 2023Assignee: GEOSCIENCE Support Services, Inc.Inventors: Dennis E. Williams, Mark D. Williams
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Publication number: 20210393569Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.Type: ApplicationFiled: September 7, 2021Publication date: December 23, 2021Inventors: Michael BALTEZOR, Joseph FARTHING, Jake SITTENAUER, Jahna ESPINOSA, Samuel CAMPBELL, Matthew MCCLOREY, Julia K. FISCHER, Mark D. WILLIAMS, Gary E. CLAPP
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Patent number: 11123322Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.Type: GrantFiled: October 30, 2019Date of Patent: September 21, 2021Assignee: Crititech, Inc.Inventors: Michael Baltezor, Joseph Farthing, Jake Sittenauer, Jahna Espinosa, Samuel Campbell, Matthew McClorey, Julia K. Fischer, Mark D. Williams, Gary E. Clapp
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Patent number: 10993927Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.Type: GrantFiled: September 17, 2020Date of Patent: May 4, 2021Assignee: Crititech, Inc.Inventors: Michael Baltezor, Joseph Farthing, Jake Sittenauer, Jahna Espinosa, Samuel Campbell, Matthew McClorey, Julia K. Fischer, Mark D. Williams, Gary E. Clapp
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Publication number: 20210000786Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.Type: ApplicationFiled: September 17, 2020Publication date: January 7, 2021Inventors: Michael BALTEZOR, Joseph FARTHING, Jake SITTENAUER, Jahna ESPINOSA, Samuel CAMPBELL, Matthew MCCLOREY, Julia K. FISCHER, Mark D. WILLIAMS, Gary E. CLAPP
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Publication number: 20200405684Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.Type: ApplicationFiled: September 16, 2020Publication date: December 31, 2020Inventors: Michael BALTEZOR, Joseph FARTHING, Jake SITTENAUER, Jahna ESPINOSA, Samuel CAMPBELL, Matthew MCCLOREY, Julia K. FISCHER, Mark D. WILLIAMS, Gary E. CLAPP
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Publication number: 20200355067Abstract: Systems and methods corresponding with improved wellfield management are provided. In some examples, the system may initiate a step drawdown test of well efficiency to determine a cause of a decreased discharge rate of the wellfield site. The system may alter pumping of the wellfield site based on the step drawdown test, wherein a command signal is transmitted via a SCADA system to the wellfield site.Type: ApplicationFiled: May 8, 2020Publication date: November 12, 2020Applicant: GEOSCIENCE Support Services, Inc.Inventors: Dennis E. Williams, Mark D. Williams
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Patent number: 10729673Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.Type: GrantFiled: January 30, 2020Date of Patent: August 4, 2020Assignee: Crititech, Inc.Inventors: Michael Baltezor, Joseph Farthing, Jake Sittenauer, Jahna Espinosa, Samuel Campbell, Matthew McClorey, Julia K. Fischer, Mark D. Williams, Gary E. Clapp
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Publication number: 20200163928Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.Type: ApplicationFiled: January 30, 2020Publication date: May 28, 2020Inventors: Michael BALTEZOR, Joseph FARTHING, Jake SITTENAUER, Jahna ESPINOSA, Samuel CAMPBELL, Matthew MCCLOREY, Julia K. FISCHER, Mark D. WILLIAMS, Gary E. CLAPP
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Publication number: 20200101039Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.Type: ApplicationFiled: October 30, 2019Publication date: April 2, 2020Inventors: Michael BALTEZOR, Joseph FARTHING, Jake SITTENAUER, Jahna ESPINOSA, Samuel CAMPBELL, Matthew MCCLOREY, Julia K. FISCHER, Mark D. WILLIAMS, Gary E. CLAPP
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Patent number: 10507195Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.Type: GrantFiled: February 13, 2018Date of Patent: December 17, 2019Assignee: Crititech, Inc.Inventors: Michael Baltezor, Joseph Farthing, Jake Sittenauer, Jahna Espinosa, Samuel Campbell, Matthew McClorey, Julia K. Fischer, Mark D. Williams, Gary Clapp
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Publication number: 20180169058Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.Type: ApplicationFiled: February 13, 2018Publication date: June 21, 2018Inventors: Michael BALTEZOR, Joseph FARTHING, Jake SITTENAUER, Jahna ESPINOSA, Samuel CAMPBELL, Matthew MCCLOREY, Julia K. FISCHER, Mark D. WILLIAMS, Gary CLAPP
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Patent number: 9918957Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.Type: GrantFiled: April 27, 2017Date of Patent: March 20, 2018Assignee: Crititech, Inc.Inventors: Michael Baltezor, Joseph Farthing, Jake Sittenauer, Jahna Espinosa, Samuel Campbell, Matthew McClorey, Julia K. Fischer, Mark D. Williams
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Patent number: 9814685Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.Type: GrantFiled: June 6, 2016Date of Patent: November 14, 2017Assignee: Crititech, Inc.Inventors: Michael Baltezor, Joseph Farthing, Jake Sittenauer, Jahna Espinosa, Samuel Campbell, Matthew McClorey, Julia K. Fischer, Mark D. Williams, Gary E. Clapp
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Publication number: 20170224650Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.Type: ApplicationFiled: April 27, 2017Publication date: August 10, 2017Inventors: Michael BALTEZOR, Joseph FARTHING, Jake SITTENAUER, Jahna ESPINOSA, Samuel CAMPBELL, Matthew MCCLOREY, Julia K. FISCHER, Mark D. WILLIAMS