Abstract: A field spectral radiometer includes a support structure and a remote sensing head disposed on the support structure. The remote sensing head includes a central axis, a first optical element disposed on a first side of the central axis and defining a first optical path for a first optical channel, and a second optical element disposed on a second side of the central axis and defining second optical path for a second optical channel. An instrumentation assembly disposed on the support structure. the instrumentation assembly includes a first detection path associated with the first optical channel and a second detection path associated with the second optical channel, the first and second detection path include optical indexers for manipulating the first and second optical channels. The field spectral radiometer may include a calibration assembly disposed on the base. The calibration assembly may include a calibrating light source for calibrating the remote sensing head.

Abstract: A reflector array includes a base, a rotating support pivotally coupled to the base, and an array actuator comprising a rotating element coupled to the rotating support. The reflector array also includes a plurality of reflectors attached to the rotating support such that the plurality of reflectors rotate in unison in conjunction with one another relative to the base as the array actuator rotates the rotating element. First and second reflectors are coupled to the rotating support via separate reflector support elements that are rotatable to adjust elevation angles of the first and second reflectors.

Abstract: An illumination system includes an illumination source configured to emit illumination light and a dispersive optical element configured to generate an angularly dispersed optical signal from the illumination light that is used to generate a spectral image. A digital micro-mirror device (DMD) includes an array of reflective elements that receive the spectral image and direct a portion of the spectral image to an integrating sphere. A controller is configured to calculate a subset of an array of reflective elements of the DMD to activate based on a target illumination output signal using a calibration model of the illumination system. The controller is also configured to activate the subset of the array of reflective elements to change the portion of the spectral image directed to the integrating sphere to generate an illumination output signal that substantially matches the target illumination output signal.

Abstract: An illumination system includes an illumination source configured to emit illumination light and a dispersive optical element configured to generate an angularly dispersed optical signal from the illumination light that is used to generate a spectral image. A digital micro-mirror device (DMD) includes an array of reflective elements that receive the spectral image and direct a portion of the spectral image to an integrating sphere. A controller is configured to calculate a subset of an array of reflective elements of the DMD to activate based on a target illumination output signal using a calibration model of the illumination system. The controller is also configured to activate the subset of the array of reflective elements to change the portion of the spectral image directed to the integrating sphere to generate an illumination output signal that substantially matches the target illumination output signal.

Abstract: A reflector array includes a base, a rotating support pivotally coupled to the base, and an array actuator comprising a rotating element coupled to the rotating support. The reflector array also includes a plurality of reflectors attached to the rotating support such that the plurality of reflectors rotate in unison in conjunction with one another relative to the base as the array actuator rotates the rotating element. First and second reflectors are coupled to the rotating support via separate reflector support elements that are rotatable to adjust elevation angles of the first and second reflectors.

Abstract: A field spectral radiometer includes a support structure and a remote sensing head disposed on the support structure. The remote sensing head includes a central axis, a first optical element disposed on a first side of the central axis and defining a first optical path for a first optical channel, and a second optical element disposed on a second side of the central axis and defining second optical path for a second optical channel. An instrumentation assembly disposed on the support structure. the instrumentation assembly includes a first detection path associated with the first optical channel and a second detection path associated with the second optical channel, the first and second detection path include optical indexers for manipulating the first and second optical channels. The field spectral radiometer may include a calibration assembly disposed on the base. The calibration assembly may include a calibrating light source for calibrating the remote sensing head.

Abstract: A system for calibrating a plurality of user sensors includes a calibration management system comprising a processor and a node services module and a plurality of calibration nodes disposed at a plurality of geographical locations. The processor is communicably coupled to the plurality of user sensors, the node services module, and the plurality of calibration nodes and operable to: provide calibration node information to a system associated with one of the plurality of user sensors and cause the calibration node to perform at least one calibration action after providing the calibration information, the calibration action may include performing an environmental measurement and/or providing a calibration reference signal to the user sensor. The processor is also operable to provide calibration results information containing results of the calibration action to the system associated with the one of the plurality of user sensors.

Abstract: The invention features thrombospondin-1 (TSP-1) polypeptides (e.g., 3TSR-Fc fusion proteins), nucleic acid molecules encoding the TSP-1 polypeptides, and compositions thereof. The invention also features methods of making and using the TSP-1 polypeptides of the invention (e.g., using 3TSR-Fc fusion proteins to treat a subject having a disorder associated with pathological angiogenesis, e.g., cancer, e.g., epithelial ovarian cancer (EOC)).

Abstract: The invention features thrombospondin-1 (TSP-1) polypeptides (e.g., 3TSR-Fc fusion proteins), nucleic acid molecules encoding the TSP-1 polypeptides, and compositions thereof. The invention also features methods of making and using the TSP-1 polypeptides of the invention (e.g., using 3TSR-Fc fusion proteins to treat a subject having a disorder associated with pathological angiogenesis, e.g., cancer, e.g., epithelial ovarian cancer (EOC)).

Abstract: The invention features thrombospondin-1 (TSP-1) polypeptides (e.g., 3TSR-Fc fusion proteins), nucleic acid molecules encoding the TSP-1 polypeptides, and compositions thereof. The invention also features methods of making and using the TSP-1 polypeptides of the invention (e.g., using 3TSR-Fc fusion proteins to treat a subject having a disorder associated with pathological angiogenesis, e.g., cancer, e.g., epithelial ovarian cancer (EOC)).

Abstract: A data warehouse for historic projects can be maintained and can include different artifacts per project, human and organizational resources consumed, intra-artifact temporal dependencies, and timelines. A set of parameters for a new project can be received which can define a scope of the new project at a level of abstraction above an artifact level. Key artifacts and stages needed for completing the project can be established which can be consistent with the set of parameters. Two or more historic projects can be determined to have artifacts/stages similar to the key artifacts/stages of the project. A data driven heuristic algorithms can estimate timelines for producing the key artifacts and the stages based on artifact level data for the historic projects can be executed. A schedule for the project can be generated which can break down the project by the stages and the key artifacts and provide the estimated timelines.

Abstract: A data warehouse for historic projects can be maintained and can include different artifacts per project, human and organizational resources consumed, intra-artifact temporal dependencies, and timelines. A set of parameters for a new project can be received which can define a scope of the new project at a level of abstraction above an artifact level. Key artifacts and stages needed for completing the project can be established which can be consistent with the set of parameters. Two or more historic projects can be determined to have artifacts/stages similar to the key artifacts/stages of the project. A data driven heuristic algorithms can estimate timelines for producing the key artifacts and the stages based on artifact level data for the historic projects can be executed. A schedule for the project can be generated which can break down the project by the stages and the key artifacts and provide the estimated timelines.

Abstract: A unit pump (10) is provided with a bleed port (12) spaced from the main injection port (14). The bleed port (12) improves the rate shape of injection through an associated fuel injector by slowing the initial rate of injection. The bleed port (12) permits shifting of the engine speed at which speed advance occurs. The bleed port (12) also flattens the fuel backup curve. Altering the cross section flow area (18) of the bleed port, axial spacing between the bleed port and inlet port (20) permit the designer to vary (or even eliminate) the impact of the bleed port (12) on the unit pump (10) performance.

Abstract: A hydraulically actuated servo piston and hydraulic advance piston are integrated into the cam follower of a unit pump or injector to provide variable advance for an injection event produced by the pump or injector. The servo piston is nested in the advance piston with fluid passageways in the advance piston selectively opened or closed by movement of the servo piston. The full pressure of a hydraulic pump is available to the advance piston for powering the advance function, while stepwise reduced levels of hydraulic pressure from the same hydraulic pump are applied to control movement of the servo piston. A damping orifice restricts flow of hydraulic fluid to and from the servo piston.

Abstract: A fuel injector unit pump, driven by a cam function to supply fuel to an injector for an injection event. The fuel injector unit pump includes a body and a pumping plunger reciprocably disposed within the body and has a driven end. A cam follower assembly is provided for engaging the cam and includes an advance piston that engages the driven end of the pumping plunger for advancing or retarding the timing of the injection event. The advance piston is movable in response to fluid pressure controlled by an advance control. A follower return spring is disposed between the body and the cam follower assembly and a plunger return spring is mounted coaxially with the follower return spring and between the body and the advance piston. The advance piston includes a main cavity and the cam follower assembly includes a housing and the fuel injector unit pump may also include a balance spring disposed between the main cavity of the advance piston and the housing of the cam follower assembly.

Abstract: A hydraulically actuated servo piston and hydraulic advance piston are integrated into the cam follower of a unit pump or injector to provide variable advance for an injection event produced by the pump or injector. The servo piston is nested in the advance piston with fluid passageways in the advance piston selectively opened or closed by movement of the servo piston. The full pressure of a hydraulic pump is available to the advance piston for powering the advance function, while stepwise reduced levels of hydraulic pressure from the same hydraulic pump are applied to control movement of the servo piston. A damping orifice restricts flow of hydraulic fluid to and from the servo piston.