Patents by Inventor Mark F. Smith
Mark F. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11994857Abstract: A system and method for operation of an autonomous vehicle (AV) yard truck is provided. A processor facilitates autonomous movement of the AV yard truck, and connection to and disconnection from trailers. A plurality of sensors are interconnected with the processor that sense terrain/objects and assist in automatically connecting/disconnecting trailers. A server, interconnected, wirelessly with the processor, that tracks movement of the truck around and determines locations for trailer connection and disconnection. A door station unlatches/opens rear doors of the trailer when adjacent thereto, securing them in an opened position via clamps, etc. The system computes a height of the trailer, and/or if landing gear of the trailer is on the ground and interoperates with the fifth wheel to change height, and whether docking is safe, allowing a user to take manual control, and optimum charge time(s). Reversing sensors/safety, automated chocking, and intermodal container organization are also provided.Type: GrantFiled: February 21, 2019Date of Patent: May 28, 2024Assignee: Outrider Technologies, Inc.Inventors: Andrew F. Smith, Lawrence S. Klein, Stephen A. Langenderfer, Martin E. Sotola, Vikas Bahl, Mark H. Rosenblum, Peter James, Dale Rowley, Matthew S. Johannes, Gary Seminara, Jeremy M. Nett
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Publication number: 20240152139Abstract: A system and method for operation of an autonomous vehicle (AV) yard truck is provided. A processor facilitates autonomous movement of the AV yard truck, and connection to and disconnection from trailers. A plurality of sensors are interconnected with the processor that sense terrain/objects and assist in automatically connecting/disconnecting trailers. A server, interconnected, wirelessly with the processor, that tracks movement of the truck around and determines locations for trailer connection and disconnection. A door station unlatches/opens rear doors of the trailer when adjacent thereto, securing them in an opened position via clamps, etc. The system computes a height of the trailer, and/or if landing gear of the trailer is on the ground and interoperates with the fifth wheel to change height, and whether docking is safe, allowing a user to take manual control, and optimum charge time(s). Reversing sensors/safety, automated chocking, and intermodal container organization are also provided.Type: ApplicationFiled: October 9, 2023Publication date: May 9, 2024Inventors: Andrew F. Smith, Lawrence S. Klein, Stephen A. Langenderfer, Martin E. Sotola, Vikas Bahl, Mark H. Rosenblum, Peter James, Dale Dee Rowley, Matthew S. Johannes, Gary Michael Seminara, Jeremy M. Nett
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Publication number: 20240131886Abstract: A system and method for operation of an autonomous vehicle (AV) yard truck is provided. A processor facilitates autonomous movement of the AV yard truck, and connection to and disconnection from trailers. A plurality of sensors are interconnected with the processor that sense terrain/objects and assist in automatically connecting/disconnecting trailers. A server, interconnected, wirelessly with the processor, that tracks movement of the truck around and determines locations for trailer connection and disconnection. A door station unlatches/opens rear doors of the trailer when adjacent thereto, securing them in an opened position via clamps, etc. The system computes a height of the trailer, and/or if landing gear of the trailer is on the ground and interoperates with the fifth wheel to change height, and whether docking is safe, allowing a user to take manual control, and optimum charge time(s). Reversing sensors/safety, automated chocking, and intermodal container organization are also provided.Type: ApplicationFiled: July 23, 2023Publication date: April 25, 2024Inventors: Andrew F. Smith, Lawrence S. Klein, Stephen A. Langenderfer, Martin E. Sotola, Vikas Bahl, Mark H. Rosenblum, Peter James, Dale Dee Rowley, Matthew S. Johannes, Gary Michael Seminara, Jeremy M. Nett, Christopher T. Bate, Michael Patrick Cutter
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Patent number: 11964989Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.Type: GrantFiled: July 20, 2022Date of Patent: April 23, 2024Assignees: Mirati Therapeutics, Inc., Array BioPharma Inc.Inventors: Xiaolun Wang, Aaron Craig Burns, James Gail Christensen, John Michael Ketcham, John David Lawson, Matthew Arnold Marx, Christopher Ronald Smith, Shelley Allen, James F. Blake, Mark Joseph Chicarelli, Joshua Ryan Dahlke, Donghua Dai, Jay Bradford Fell, John Peter Fischer, Macedonio J. Mejia, Brad Newhouse, Phong Nguyen, Jacob Matthew O'Leary, Spencer Pajk, Martha E. Rodriguez, Pavel Savechenkov, Tony P. Tang, Guy P.A. Vigers, Qian Zhao, Dean Russell Kahn, John Gaudino, Michael Christopher Hilton
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Publication number: 20240101553Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.Type: ApplicationFiled: August 4, 2023Publication date: March 28, 2024Inventors: Matthew Arnold MARX, James Gail CHRISTENSEN, Christopher Ronald SMITH, James F. BLAKE, Laurence E. BURGESS, Mark Joseph CHICARELLI, Adam COOK, Jay Bradford FELL, John P. FISCHER, Macedonio J. MEJIA, Martha E. RODRIGUEZ, Pavel SAVECHENKOV, Tony P. TANG, Guy P.A. VIGERS
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Publication number: 20240081817Abstract: An orthopedic implant system can be used to fixate two bones (e.g., to portions of a single bone) relative to each other during a surgical procedure. In some configurations, the implant system includes a staple having at least two legs separated by a bridge. The staple can include at least two couplings on either side of the bridge accessible through a top surface of the staple connectable to two corresponding coupling shafts. The coupling shafts can attach through the top surface of the staple without extending below an underside of the staple. The coupling shafts can be used to bias the at least two legs of the staple away from each other for insertion into holes formed into two bones. By attaching the coupling shafts through the top of the staple, the staple can be inserted flush with the two bones before releasing the shafts.Type: ApplicationFiled: September 14, 2023Publication date: March 14, 2024Inventors: W. Bret Smith, Madeline Lindemann, Bryan Wilcox, Sean F. Scanlan, Jason May, Adriaan Kuyler, Robert D. Santrock, Mark Erik Easley
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Publication number: 20240082015Abstract: An orthopedic implant system can be used to fixate two vertebral bones relative to each other during a surgical procedure. In some configurations, the implant system includes a staple having at least two legs separated by a bridge. The staple can include at least two couplings on either side of the bridge accessible through a top surface of the staple connectable to two corresponding coupling shafts. The coupling shafts can attach through the top surface of the staple without extending below an underside of the staple. The coupling shafts can be used to bias the at least two legs of the staple away from each other for insertion into holes formed into two bones. By attaching the coupling shafts through the top of the staple, the staple can be inserted flush with the two bones before releasing the shafts.Type: ApplicationFiled: September 14, 2023Publication date: March 14, 2024Inventors: W. Bret Smith, Madeline Lindemann, Bryan Wilcox, Sean F. Scanlan, Jason May, Adriaan Kuyler, Robert D. Santrock, Mark Erik Easley
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Publication number: 20240081816Abstract: An orthopedic implant system can be used to fixate two bones (e.g., to portions of a single bone) relative to each other during a surgical procedure. In some configurations, the implant system includes a staple having at least two legs separated by a bridge. The staple can include at least two couplings on either side of the bridge accessible through a top surface of the staple connectable to two corresponding coupling shafts. The coupling shafts can attach through the top surface of the staple without extending below an underside of the staple. The coupling shafts can be used to bias the at least two legs of the staple away from each other for insertion into holes formed into two bones. By attaching the coupling shafts through the top of the staple, the staple can be inserted flush with the two bones before releasing the shafts.Type: ApplicationFiled: September 14, 2023Publication date: March 14, 2024Inventors: W. Bret Smith, Madeline Lindemann, Bryan Wilcox, Sean F. Scanlan, Jason May, Adriaan Kuyler, Robert D. Santrock, Mark Erik Easley
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Publication number: 20240081843Abstract: Systems, techniques, and devices are described that may be used in a minimally invasive bone realignment procedure. In some examples, a method of performing a minimally invasive metatarsal correction procedure involves using a bone preparation guide having a guide surface with a length less than a diameter of a bone to be cut using the guide surface. The clinician can guide a bone preparation instrument along the guide surface and angle the bone preparation instrument beyond one or both ends of the guide surface to cut the end of the underlying bone beyond one or both of the ends.Type: ApplicationFiled: September 14, 2023Publication date: March 14, 2024Inventors: Adriaan Kuyler, Paul Dayton, Mark Erik Easley, William T. DeCarbo, Daniel J. Hatch, Jody McAleer, Robert D. Santrock, W. Bret Smith, Sean F. Scanlan, Jason May, Michael Stedham
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Patent number: 11860197Abstract: A sensor/transducer for use in reducing leakage current from a patient fluidly connected to a medical device by tubing filled with a conductive fluid (e.g., blood or dialysate (a “fluid line”)) includes a magnetically conductive core with 1) a centrally located support for a coil of fluid line, and 2) coiled electrical conductors located at positions that are spaced from the centrally located support, on opposite sides of the centrally located support. The sensor/transducer can be used to measure leakage current carried by the conductive fluid in the fluid line, or it can be used to induce current in the fluid line in a manner that reduces the leakage current.Type: GrantFiled: November 18, 2021Date of Patent: January 2, 2024Assignee: NxStage Medical, Inc.Inventor: Mark F. Smith
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Publication number: 20230277744Abstract: Methods and systems for reducing electrical leakage current between a patient and a medical device include sensing electrical current in a fluid line and inducing a cancelling electrical current or voltage to reduce the electrical leakage current. A system for implementing the method includes one or more sensors/transducers and a controller that drives the transducer(s) based on signals from the sensor(s).Type: ApplicationFiled: July 14, 2021Publication date: September 7, 2023Applicant: NxStage Medical, Inc.Inventors: Mark F. SMITH, Ilya KARNAUK, Eric ZOGLIO
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Patent number: 11544852Abstract: A performance scanning system that operates to detect and measure surface parameters of a portion of an athlete and uses the surface parameters to determine the likelihood that the athlete's physical performance has been or will be impaired.Type: GrantFiled: December 4, 2018Date of Patent: January 3, 2023Inventors: Paul E. Thomson, Mark F. Smith
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Publication number: 20220196708Abstract: A sensor/transducer for use in reducing leakage current from a patient fluidly connected to a medical device by tubing filled with a conductive fluid (e.g., blood or dialysate (a “fluid line”)) includes a magnetically conductive core with 1) a centrally located support for a coil of fluid line, and 2) coiled electrical conductors located at positions that are spaced from the centrally located support, on opposite sides of the centrally located support. The sensor/transducer can be used to measure leakage current carried by the conductive fluid in the fluid line, or it can be used to induce current in the fluid line in a manner that reduces the leakage current.Type: ApplicationFiled: November 18, 2021Publication date: June 23, 2022Applicant: NxStage Medical, Inc.Inventor: Mark F. SMITH
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Publication number: 20210183063Abstract: A performance scanning system that operates to detect and measure surface parameters of a portion of an athlete and uses the surface parameters to determine the likelihood that the athlete's physical performance has been or will be impaired.Type: ApplicationFiled: December 4, 2018Publication date: June 17, 2021Applicant: Ectoscan Systems, LLCInventors: Paul E. Thomson, Mark F. Smith
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Publication number: 20200406193Abstract: The present invention is directed toward a dialysis unit that is modular and portable, with improved functionality. In one embodiment, the dialysis system comprises a top unit that is detachably affixed to a base that comprises a reservoir for fluid storage. Among numerous other features, the portable, modular dialysis system of the present invention has improved power door locking, zoned leak detection, fluid handling, and mechanical design features that enable improved modularity.Type: ApplicationFiled: July 7, 2020Publication date: December 31, 2020Inventors: Barry Neil Fulkerson, Martin Hering, Mark F. Smith, Jan B. Zwierstra
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Patent number: 10758868Abstract: The present invention is directed toward a dialysis unit that is modular and portable, with improved functionality. In one embodiment, the dialysis system comprises a top unit that is detachably affixed to a base that comprises a reservoir for fluid storage. Among numerous other features, the portable, modular dialysis system of the present invention has improved power door locking, zoned leak detection, fluid handling, and mechanical design features that enable improved modularity.Type: GrantFiled: May 22, 2018Date of Patent: September 1, 2020Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Barry Neil Fulkerson, Martin Hering, Mark F. Smith, Jan B. Zwierstra
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Patent number: 10252827Abstract: A packaging system and method for receiving articles from a first location, such as a product delivery system, transporting the articles to a second location for unloading the articles such that they are placed in a desired orientation and number of columns, rows, and stacks.Type: GrantFiled: May 31, 2018Date of Patent: April 9, 2019Assignee: Rockwell Automation, Inc.Inventors: Keith G. Jacobs, Glen C. Wenersbach, Mark F. Smith
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Publication number: 20180339269Abstract: The present invention is directed toward a dialysis unit that is modular and portable, with improved functionality. In one embodiment, the dialysis system comprises a top unit that is detachably affixed to a base that comprises a reservoir for fluid storage. Among numerous other features, the portable, modular dialysis system of the present invention has improved power door locking, zoned leak detection, fluid handling, and mechanical design features that enable improved modularity.Type: ApplicationFiled: May 22, 2018Publication date: November 29, 2018Inventors: Barry Neil Fulkerson, Martin Hering, Mark F. Smith, Jan B. Zwierstra
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Publication number: 20180273222Abstract: A packaging system and method for receiving articles from a first location, such as a product delivery system, transporting the articles to a second location for unloading the articles such that they are placed in a desired orientation and number of columns, rows, and stacks.Type: ApplicationFiled: May 31, 2018Publication date: September 27, 2018Inventors: Keith G. Jacobs, Glen C. Wenersbach, Mark F. Smith
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Patent number: 10035103Abstract: The present invention is directed toward a dialysis unit that is modular and portable, with improved functionality. In one embodiment, the dialysis system comprises a top unit that is detachably affixed to a base that comprises a reservoir for fluid storage. Among numerous other features, the portable, modular dialysis system of the present invention has improved power door locking, zoned leak detection, fluid handling, and mechanical design features that enable improved modularity.Type: GrantFiled: October 30, 2009Date of Patent: July 31, 2018Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Barry Neil Fulkerson, Martin Hering, Mark F. Smith, Jan B. Zwierstra