Patents by Inventor Mark G. DeGiacomo

Mark G. DeGiacomo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic inhibitors of the sodium channel
    Patent number: 11236078
    Abstract: The invention relates to compounds useful in treating conditions associated with voltage-gated ion channel function, particularly conditions associated with sodium channel activity. More specifically, the invention concerns heterocyclic compounds (e.g., compounds according to any of Formulas (I)-(III) or Compounds (1)-(65) of Table 1) that are that are useful in treatment of conditions such as epilepsy, cancer, pain, migraine, Parkinson's Disease, mood disorders, schizophrenia, psychosis, tinnitus, amyotropic lateral sclerosis, glaucoma, ischaemia, spasticity disorders, obsessive compulsive disorder, restless leg syndrome and Tourette syndrome.
    Type: Grant
    Filed: September 23, 2019
    Date of Patent: February 1, 2022
    Inventor: Mark G. DeGiacomo
  • HETEROCYCLIC INHIBITORS OF THE SODIUM CHANNEL
    Publication number: 20200017488
    Abstract: The invention relates to compounds useful in treating conditions associated with voltage-gated ion channel function, particularly conditions associated with sodium channel activity. More specifically, the invention concerns heterocyclic compounds (e.g., compounds according to any of Formulas (I)-(III) or Compounds (1)-(65) of Table 1) that are that are useful in treatment of conditions such as epilepsy, cancer, pain, migraine, Parkinson's Disease, mood disorders, schizophrenia, psychosis, tinnitus, amyotropic lateral sclerosis, glaucoma, ischaemia, spasticity disorders, obsessive compulsive disorder, restless leg syndrome and Tourette syndrome.
    Type: Application
    Filed: September 23, 2019
    Publication date: January 16, 2020
    Inventor: Mark G. DeGiacomo
  • Benzimidazole inhibitors of the sodium channel
    Patent number: 10351514
    Abstract: The invention relates to compounds useful in treating conditions associated with voltage-gated ion channel function, particularly conditions associated with sodium channel activity. More specifically, the invention concerns compounds (e.g., compounds according to any of Formulas (I)-(XIII) and in particular Formula (X), and Compounds (1)-(236) of Table 1) that are useful in treatment of a variety of diseases and conditions.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: July 16, 2019
    Assignee: Mark G. DeGiacomo, Interim Trustee
    Inventor: Mark G. DeGiacomo
  • Heterocyclic inhibitors of the sodium channel
    Patent number: 10208023
    Abstract: The invention relates to compounds useful in treating conditions associated with voltage-gated ion channel function, particularly conditions associated with sodium channel activity. More specifically, the invention concerns heterocyclic compounds (e.g., compounds according to any of Formulas (I)-(X) or Compounds (1)-(92) of Table 1) that are that are useful in treatment of conditions such as epilepsy, cancer, pain, migraine, Parkinson's Disease, mood disorders, schizophrenia, psychosis, tinnitus, amyotrophic lateral sclerosis, glaucoma, ischemia, spasticity disorders, obsessive compulsive disorder, restless leg syndrome and Tourette syndrome.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: February 19, 2019
    Inventor: Mark G. DeGiacomo
  • Benzimidazole Inhibitors of the Sodium Channel
    Publication number: 20180111894
    Abstract: The invention relates to compounds useful in treating conditions associated with voltage-gated ion channel function, particularly conditions associated with sodium channel activity. More specifically, the invention concerns compounds (e.g., compounds according to any of Formulas (I)-(XIII) and in particular Formula (X), and Compounds (1)-(236) of Table 1) that are useful in treatment of a variety of diseases and conditions.
    Type: Application
    Filed: December 18, 2017
    Publication date: April 26, 2018
    Inventor: Mark G. DeGiacomo
  • Benzimidazole Inhibitors of the Sodium Channel
    Publication number: 20170260130
    Abstract: The invention relates to compounds useful in treating conditions associated with voltage-gated ion channel function, particularly conditions associated with sodium channel activity. More specifically, the invention concerns compounds (e.g., compounds according to any of Formulas (I)-(XIII) or Compounds (1)-(236) of Table 1) that are useful in treatment of a variety of diseases and conditions.
    Type: Application
    Filed: May 22, 2017
    Publication date: September 14, 2017
    Inventor: Mark G. DeGiacomo
  • HETEROCYCLIC INHIBITORS OF THE SODIUM CHANNEL
    Publication number: 20170145003
    Abstract: The invention relates to compounds useful in treating conditions associated with voltage-gated ion channel function, particularly conditions associated with sodium channel activity. More specifically, the invention concerns heterocyclic compounds (e.g., compounds according to any of Formulas (1)-(11 1) or Compounds (1)-(65) of Table 1) that are that are useful in treatment of conditions such as epilepsy, cancer, pain, migraine, Parkinson's Disease, mood disorders, schizophrenia, psychosis, tinnitus, amyotropic lateral sclerosis, glaucoma, ischaemia, spasticity disorders, obsessive compulsive disorder, restless leg syndrome and Tourette syndrome.
    Type: Application
    Filed: February 26, 2015
    Publication date: May 25, 2017
    Inventor: Mark G. DeGiacomo