Abstract: The present disclosure provides alfalfa plants exhibiting broad spectrum resistance to Race 1, Race 2, and Race 5 anthracnose. Such plants may comprise novel introgressed genomic regions associated with disease resistance from Race 1, Race 2, and Race 5 anthracnose. In certain aspects, compositions, including novel polymorphic markers and methods for producing, breeding, identifying, and selecting plants or germplasm with a disease resistance phenotype are provided. Also provided are alfalfa varieties designated as C0416C4164 and H0415C4114. Provided by the invention are the seeds, plants and derivatives of alfalfa varieties C0416C4164 and H0415C4114. Also provided by the invention are tissue cultures of alfalfa varieties C0416C4164 and H0415C4114, and the plants regenerated therefrom. Still further provided by the invention are methods for producing alfalfa plants by crossing alfalfa variety C0416C4164 or H0415C4114 with itself or another alfalfa variety and plants produced by such methods.

Abstract: The present disclosure relates generally to certain 6-azabenzimidazole compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions disclosed herein may be used for the treatment or prevention of diseases, disorders, or infections modifiable by hematopoietic progenitor kinase 1 (HPK1) inhibitors, such as HBV, HIV, cancer, and/or a hyper-proliferative disease.

Abstract: Methods for reducing oxygen content in an oxidized annealed metal nitride film comprising exposing the film to a plasma.

Abstract: Methods for reducing oxygen content in an oxidized annealed metal nitride film comprising exposing the film to a plasma.

Abstract: The present invention is directed to hydrogel compositions for biotechnology applications. Specifically, the invention provides hydrogels mimicking the ECM and uses thereof.

Abstract: Wellbore operations (e.g. for milling and/or drilling) are disclosed which require a reduced number of tool trips into a wellbore to create a cut-out pocket or window in a tubular such as casing in the wellbore and, in some aspects, to continue into a formation adjacent a main wellbore forming a lateral wellbore in communication with the main wellbore. Preferably one trip is required. A milling apparatus has been invented with milling apparatus for milling a tubular member and a nose cone releasably connected to the milling apparatus and releasably connectible to a diverter that directs the milling apparatus toward the tubular member. A nose cone for a milling apparatus has been invented with a body member, the body member having a mid portion, a top portion and a lower nose portion, and the top portion releasably securable to the milling apparatus and the lower nose portion releasably securable to a concave of a whipstock.

Abstract: A cutting tool has been invented for use in a wellbore to cut formation through which the wellbore extends or to cut items in the wellbore, the tool having, in one aspect, a body disposable at a desired location in the wellbore, at least one first blade pivotably mounted to the body at a first height on the body, at least one second blade pivotably mounted to the body at a second height on the body, the second height above the first height, the blades movable from a first position against the body to a second position extending out from the body for cutting, and the first blades shorter in length than the second blades.

Abstract: This invention relates to a permanent whipstock assembly which uses camming pivot arms to secure the whipstock at the desired location within a cased wellbore. Camming pivot arms are pivotally attached to the downhole end of a whipstock housing and are further attached to a slip pad. Intentionally induced relative movement of the slip pad and the whipstock housing causes the camming pivot arms to pivot in such a manner that slip pad housing 4 and slip pad 5 are forced away from each other and cammed into the cased borehole. The invention relates specifically to a device that is particularly adapted to be lowered through a small diameter and later to be activated and set in a much larger casing or hole diameter.

Abstract: A whipstock assembly is provided for lowering within a cased wellbore, cutting a window through a casing for drilling a sidetrack borehole, and retrieving with conventional fishing tools. The whipstock assembly includes two separate whipstocks having different tapers, and which are releasibly coupled for separately retrieving from the cased wellbore. A barrier member is provided to prevent a tapered face of one of the whipstocks from wedging debris between the whipstock and the casing.