Abstract: A protective cover for a dual inline memory module (DIMM) circuit card includes a pair of cover members for substantially containing the DIMM circuit card. The cover members are secured to opposite sides of the DIMM circuit card. The pair of cover members defines a socket-receiving channel between respective printed-circuit-board (PCB) mating faces of the cover members. The cover members includes a plurality of positioning features engaging the DIMM circuit card for positioning a portion of the DIMM circuit card within the socket-receiving channel.

Abstract: A capacitive load cell includes upper and lower capacitor plates and an intermediate dielectric comprising two or more layers of compressible material with diverse compressibility characteristics. The most easily compressed dielectric layer provides sensitivity to low occupant weight, while the less easily compressed dielectric layer(s) provide sensitivity to medium and high occupant weight.

Abstract: A method of selecting a virtual toy construction model, the method comprising: receiving by a host computer system a digital representation of an input toy construction model, the input toy construction model including a plurality of construction elements; generating a bill-of-materials that includes at least all construction elements of the received input construction model; performing a search in a repository of respective digital representations of a plurality of virtual toy construction models for one or more construction models that can be constructed from the set of construction elements included in the bill of materials; presenting on a client computer system at least one of the construction models identified in the search.

Abstract: A web inspection module is described for scanning an imprinted web in a printing press. The web inspection module includes a light source for illuminating a portion of the web, a contact image sensor having a plurality of sensing elements, and a processor for receiving and processing image data representative of the imprinted web.

Abstract: There is provided a communication device, and a method thereof, for managing access to protected content. The communication device comprises an application (302), a trusted file system service (316), a trusted agent (318) and a trusted content renderer (320). The application (302) requests performance of an action for the protected content (306). The trusted file system service (316) identifies the protected content (306) to the application (302). The trusted agent (318) identifies rights associated with the protected content (306) to the application (302). The trusted content renderer (320) performs the action in response to determining that the application (302) is an untrusted application having sufficient rights to perform the action.

Abstract: The present invention provides compositions containing a common ligand linked to a detectable moiety and provides methods for the preparation of such compositions. The present invention also provides methods for screening candidate ligands for binding to a NAD binding receptor, which include contacting a receptor with a candidate ligand and a composition of the invention followed by evaluation of receptor binding. The screening method of the present invention has broad applicability and can be used to screen large numbers of a wide variety of ligands. The present invention further provides methods for detecting the binding activity of a putative receptor, which include combining the putative receptor with a composition of the invention and evaluating the level of detectable moiety. The invention also provides kits useful for detection of receptors having NAD binding activity and for screening of candidate ligands that bind to a NAD binding receptor.

Abstract: A wireless communication network, and a method thereof, for communicating with a remote device (104) via a wireless link comprising a transceiver (202) and a processor (204). The transceiver (202) obtains preference information relating to the remote device (104). The processor (204) adjusts time-to-live (TTL) information of at least one media content item based on the preference information. Also, the transceiver (202) provides a first media content item and a first TTL information associated with the first media content item to the remote device (104). In addition, the processor (204) identifies a second media content item associated with the first media content item, and determines a second TTL information based on the first media content item.

Abstract: The lockable motorcycle stand is composed of two major systems: a supporting system and a restraining system. The supporting system is designed to support the weight of the motorcycle during the various uses for the lockable motorcycle stand. The supporting system is designed to use leverage to move the lockable motorcycle stand from a retracted position to an extended position, whereby the motorcycle is lifted off the ground when the lockable motorcycle stand is in the extended position. The restraining system is designed to lock the lockable motorcycle stand into the extended position, securing the motorcycle to the lockable motorcycle stand thereby facilitating repairs, storage, or transport.

Abstract: An embossing system is provided for embossing a web having a first embossing roll having embossing elements and a second embossing roll having embossing elements, wherein at least a portion of the embossing elements of the first and second embossing rolls are substantially oriented in the cross-machine direction. The embossing roll may be crowned, may have alignment means, and may be provided with precision gearing.

Abstract: The present invention provides common ligand mimics that act as common ligands for a receptor family. The present invention also provides bi-ligands containing these common ligand mimics. Bi-ligands of the invention provide enhanced affinity and/or selectivity of ligand binding to a receptor or receptor family through the synergistic action of the common ligand mimic and specificity ligand which compose the bi-ligand. The present invention also provides combinatorial libraries containing the common ligand mimics and bi-ligands of the invention. Further, the present invention provides methods for manufacturing the common ligand mimics and bi-ligands of the invention and methods for assaying the combinatorial libraries of the invention.

Abstract: The present invention provides common ligand mimics that act as common ligands for a receptor family. The present invention also provides bi-ligands containing these common ligand mimics. Bi-ligands of the invention provide enhanced affinity and/or selectivity of ligand binding to a receptor or receptor family through the synergistic action of the common ligand mimic and specificity ligand that compose the bi-ligand. The present invention also provides combinatorial libraries containing the common ligand mimics and bi-ligands of the invention. Further, the present invention provides methods for manufacturing the common ligand mimics and bi-ligands of the invention and methods for assaying the combinatorial libraries of the invention.

Abstract: A chair assembly is provided which includes a frame, and a support member a support member is attached to the frame for defining a seat portion, a transition portion and a back portion. The frame is selectively movable between a collapsed position and an operative position, in the operative position a portion of the frame supporting the back portion of the support member is substantially vertically disposed and extends upward to the back portion of the support member. The chair assembly further includes an elongated member detachably connected to the substantially vertically disposed portion of the frame when the frame is in the operative position and an umbrella. A distal end portion of the shaft of the umbrella is pivotally connected to an upper end of the elongated member via a pivot assembly such that the umbrella can be selectively disposed in predetermined positions relative to the frame of the chair assembly.

Abstract: The present invention provides packaging cell lines and recombinant lentiviral or retroviral particles produced therefrom, particularly pseudotyped retroviral particles. The packaging cell lines of the invention are produced by inducibly expressing an envelope protein by methods described herein. Also described is a screening assay for compounds that affect integration of viral nucleic acid into target (e.g., host) nucleic acid. Such compounds are identified based on their effect on viral integrase.

Abstract: The present invention provides common ligand mimics that act as common ligands for a receptor family. The present invention also provides bi-ligands containing these common ligand mimics. Bi-ligands of the invention provide enhanced affinity and/or selectivity of ligand binding to a receptor or receptor family through the synergistic action of the common ligand mimic and specificity ligand which compose the bi-ligand. The present invention also provides combinatorial libraries containing the common ligand mimics and bi-ligands of the invention. Further, the present invention provides methods for manufacturing the common ligand mimics and bi-ligands of the invention and methods for assaying the combinatorial libraries of the invention.

Abstract: The present invention provides common ligand mimics that act as common ligands for a receptor family. The present invention also provides bi-ligands containing these common ligand mimics. Bi-ligands of the invention provide enhanced affinity and/or selectivity of ligand binding to a receptor or receptor family through the synergistic action of the common ligand mimic and specificity ligand that compose the bi-ligand. The present invention also provides combinatorial libraries containing the common ligand mimics and bi-ligands of the invention. Further, the present invention provides methods for manufacturing the common ligand mimics and bi-ligands of the invention and methods for assaying the combinatorial libraries of the invention.

Abstract: The invention provides a method for identifying a pharmacocluster. The method includes the steps of (a) determining bound conformations of a ligand bound to different polypeptides, and (b) clustering two or more bound conformations of the ligand having substantially the same bound conformation, thereby identifying a pharmacocluster. The invention also provides a method for identifying a member of a pharmacocluster. The invention also provides a method for identifying a polypeptide pharmacofamily. The method includes the steps of (a) determining bound conformations of a ligand bound to different polypeptides of a polypeptide family, and (b) identifying two or more bound conformations of the ligand having substantially different bound conformations, thereby identifying at least two polypeptide pharmacofamilies exhibiting binding specificity for the two or more substantially different bound conformations of the ligand.

Abstract: A system and method for information searching comprising determination of, in fine granularity, a Community of Interest (COI), further data mining in search results, using at least one of COI and expert preferences to identify important knowledge, formulation and manipulation of results, and summarization of search results into a document like entity with dynamic attributes described. More particularly, the invention relates to a system and method for providing interactive dialogue and iterative search functions to find information on a large network of servers such as the world wide web.

Abstract: The invention provides a method for identifying a pharmacocluster. The method includes the steps of (a) determining bound conformations of a ligand bound to different polypeptides, and (b) clustering two or more bound conformations of the ligand having substantially the same bound conformation, thereby identifying a pharmacocluster. The invention also provides a method for identifying a member of a pharmacocluster. The invention also provides a method for identifying a polypeptide pharmacofamily. The method includes the steps of (a) determining bound conformations of a ligand bound to different polypeptides of a polypeptide family, and (b) identifying two or more bound conformations of the ligand having substantially different bound conformations, thereby identifying at least two polypeptide pharmacofamilies exhibiting binding specificity for the two or more substantially different bound conformations of the ligand.

Abstract: The present invention provides packaging cell lines and recombinant lentiviral or retroviral particles produced therefrom, particularly pseudotyped retroviral particles. The packaging cell lines of the invention are produced by inducibly expressing an envelope protein by methods described herein. Also described is a screening assay for compounds that affect integration of viral nucleic acid into target (e.g., host) nucleic acid. Such compounds are identified based on their effect on viral integrase.

Abstract: The present invention provides packaging cell lines and recombinant lentiviral or retroviral particles produced therefrom, particularly pseudotyped retroviral particles. The packaging cell lines of the invention are produced by inducibly expressing an envelope protein by methods described herein. Also described is a screening assay for compounds that affect integration of viral nucleic acid into target (e.g., host) nucleic acid. Such compounds are identified based on their effect on viral integrase.