Abstract: A group head (20) for an espresso machine (10), the group head (20) comprising: a group head bracket (36) for detachable engagement with a portafilter (30) holding a puck (22) of ground coffee in a filter basket (64) to dispense an espresso coffee; a conduit (34) for receiving a flow of water to the portafilter (30); and, a heater (32) mounted in the group head (20) to heat the flow of water to the portafilter (30).

Abstract: The present disclosure relates generally to methods for creating a product package for a user using that take into account both static and dynamic loyalty criteria. The present invention is particularly adapted to utilization by sectors such as the agricultural industry where real time updates along a supply chain would be beneficial to suppliers and distributors.

Abstract: The presently disclosed subject matter relates to nitric oxide-releasing particles for delivering nitric oxide, and their use in biomedical and pharmaceutical applications.

Abstract: A system for performing spinal cord stimulation on a subject is disclosed. The system comprises one or more recording arrays, at least one stimulation array, and a processor. The recording arrays, which may be minimally invasively inserted to a target recording site of the brain, include recording electrodes having a diameter of less than about 1 mm and having a spacing of less than about 1 mm therebetween. The stimulation array, which may be minimally invasively inserted to a target stimulation site within the nervous tissue, includes stimulation electrodes. The processor is configured to receive more recorded signals from the recording arrays at the target recording site, determine an electrophysiological state of the brain based on the recorded signals, and deliver electrical stimulation to the target stimulation site through the stimulation array based on the determined electrophysiological state in order to affect the electrophysiological state.

Abstract: A system for performing deep brain stimulation on a brain of a patient is disclosed. The system comprises one or more recording arrays, at least one stimulation array, and a processor. The recording arrays, which may be minimally invasively inserted to a target recording site of the brain, include recording electrodes having a diameter of less than about 1 mm and having a spacing of less than about 1 mm therebetween. The stimulation array, which may be inserted to a target stimulation site within the deep brain, includes at least one stimulation electrode. The processor is configured to receive one or more recorded signals from the recording arrays at the target recording site, determine a neurological state of the brain based on the recorded signals, and deliver electrical stimulation to the target stimulation site through the stimulation array based on the neurological state in order to electrically stimulate the brain.

Abstract: Disclosed herein are systems and methods for neural interfaces. Neural interfaces may form minimally invasive and high-scalable bidirectional brain-computer interfaces, which may be used in the treatment of a variety of disorders of the brain and nervous system. Disclosed are methods for a minimally invasive technique for implanting neural interfaces, a neural interface configured to be placed between the brain and the dura and configured to record from and/or stimulate the cortical surface. Also disclosed are methods for attaching a plurality of microelectrode arrays to form a neural interface device, and fabricating neural interfaces including microelectrode arrays and pockets to facilitate their insertion. The disclosed systems and methods also include neural decoding techniques.

Abstract: A cordless portable composite foam roller generates and applies heat and/or cold to muscles, and operates using an internal rechargeable power source combined with a flex-proof heating layer when in use. The cordless foam roller includes an elongated cylindrically-shaped body having a sandwich of heating layer(s) and textured exterior surface, and an inner cavity for hosting the rechargeable power source components.

Abstract: The various implementations described herein include a video camera assembly that includes: (1) a housing; (2) an image sensor encased in the housing and configured to capture activity of the smart home environment; (3) a wireless radio configured to transmit video frames captured by the image sensor to an electronic device via a remote server; (4) at least one infrared transmitter configured to selectively illuminate the smart home environment; (5) one or more circuit boards encased in the housing, the one or more circuit boards including at least one processor mounted thereon; and (6) a heating component coupled to the image sensor, the heating component configured to continuously maintain the image sensor at a temperature above a threshold temperature while the image sensor is capturing the activity of the smart home environment.

Abstract: Provided herein is A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the various substituents are described herein.

Abstract: A dispenser including a decorative housing, fluid storage internal to the decorative housing, and a fluid dispenser in fluid communication with the fluid storage. The dispenser also includes one or more movable decorative elements, an activator in communication with the fluid dispenser, and a sound emitter. Upon operation of the fluid dispenser fluid is dispensed from the fluid storage and the activator is triggered initiating the sound emitter to produce sound and further initiating movement of one or more moveable decorative elements.

Abstract: Compositions comprising one or more practically insoluble proteasome inhibitors and a cyclodextrin, particularly a substituted cyclodextrin, substantially increase the solubility of these proteasome inhibitors and facilitate their administration. Such compositions optionally comprise a buffer. Methods of treatment using such compositions are also disclosed.

Abstract: The present invention relates to a container with a structural improvement. The improvement comprises one transparent hollow vessel, at least one circular dividing board and at least one reservoir for containing either liquid and/or solid, wherein the transparent hollow vessel has a first end and a second end, the first end further comprising a threaded sleeve, the second end of the transparent hollow vessel at an appropriate location having a water intake opening. The second end of the transparent hollow vessel is matingly-fitted with the circular dividing board, wherein the center of the circular dividing board has an opening to receive a dispensing tube, the dispensing tube positioned between the opening of the circular dividing board and the threaded sleeve of the first end of the transparent hollow vessel. The reservoir is matingly-fitted and positioned below the transparent hollow vessel.

Abstract: Disclosed and claimed is a dispenser, such as a pump, pour or aerosol dispenser, for dispensing a liquid from a reservoir, and methods for making and using the dispenser. The dispenser includes a hollow decorative vessel having a decorative element. The decorative vessel is capable of containing a first liquid. The reservoir is connected to the hollow decorative vessel. The reservoir is capable of containing a second liquid and having an interior therefor. And, the dispenser includes apparatus for dispensing the second liquid from the interior of the reservoir. The dispenser can include the first liquid and particles in suspension for a period of time when the liquid is shaken, such that the hollow decorative vessel can be a “snow globe”. The hollow decorative vessel can be positioned atop the reservoir or, below the reservoir. Alternatively, the hollow decorative vessel can be surrounded by the reservoir. And as another alternative, the hollow decorative vessel can contain the reservoir.

Abstract: The present invention relates to a container with a structural improvement. The improvement comprises one transparent hollow vessel, at least one circular dividing board and at least one reservoir for containing either liquid and/or solid, wherein the transparent hollow vessel has a first end and a second end, the first end further comprising a threaded sleeve, the second end of the transparent hollow vessel at an appropriate location having a water intake opening. The second end of the transparent hollow vessel is matingly-fitted with the circular dividing board, wherein the center of the circular dividing board has an opening to receive a dispensing tube, the dispensing tube positioned between the opening of the circular dividing board and the threaded sleeve of the first end of the transparent hollow vessel. The reservoir is matingly-fitted and positioned below the transparent hollow vessel.

Abstract: Disclosed and claimed is a dispenser, such as a pump, pour or aerosol dispenser, for dispensing a liquid from a reservoir, and methods for making and using the dispenser. The dispenser includes a hollow decorative vessel having a decorative element. The decorative vessel is capable of containing a first liquid. The reservoir is connected to the hollow decorative vessel. The reservoir is capable of containing a second liquid and having an interior therefor. And, the dispenser includes apparatus for dispensing the second liquid from the interior of the reservoir. The dispenser can include the first liquid and particles in suspension for a period of time when the liquid is shaken, such that the hollow decorative vessel can be a "snow globe". The hollow decorative vessel can be positioned atop the reservoir or, below the reservoir. Alternatively, the hollow decorative vessel can be surrounded by the reservoir. And as another alternative, the hollow decorative vessel can contain the reservoir.

Abstract: A cooling device for cooling plastic particles includes a casing having a hub extended upward from an inner and lower portion for forming an annular chamber between the casing and the hub. A water is supplied into the annular chamber for moving the plastic particles upward and out through the hub, such that the plastic particles may be cooled by the water. A housing is secured on top of the casing and a pipe is coupled to the housing for supplying the plastic particles into the housing and for cooling the plastic particles in the housing by the air flowing into the housing.

Abstract: The present invention relates to a collapsible hamper, used for the storage of laundry or other items comprising a rigid upper frame, a rigid lower frame, a lid movably hinged to the upper frame, a flexible side wall woven out of polypropylene strips, fabric or other weavable material, and a plurality of supporting rods removably secured between the upper and lower rigid frames, which define a three dimensional internal storage space and decorative external structure that is attractive to the eye when the hamper is assembled for use and which can be easily disassembled and collapsed for convenient storage or transport when not in use.

Abstract: The present invention relates to a collapsible hamper, used for the storage of laundry or other items comprising a rigid upper frame, a rigid lower frame, a lid movably hinged to the upper frame, a flexible side wall woven out of polypropylene strips, fabric or other weavable material, and a plurality of supporting rods removably secured between the upper and lower rigid frames, which define a three dimensional internal storage space and decorative external structure that is attractive to the eye when said hamper is assembled for use and which can be easily disassembled and collapsed for convenient storage or transport when not in use.