Patents by Inventor Mark Holl

Mark Holl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240078770
    Abstract: A VR system for vehicles that may implement methods that address problems with vehicles in motion that may result in motion sickness for passengers. The VR system may provide virtual views that match visual cues with the physical motions that a passenger experiences. The VR system may provide immersive VR experiences by replacing the view of the real world with virtual environments. Active vehicle systems and/or vehicle control systems may be integrated with the VR system to provide physical effects with the virtual experiences. The virtual environments may be altered to accommodate a passenger upon determining that the passenger is prone to or is exhibiting signs of motion sickness.
    Type: Application
    Filed: September 12, 2023
    Publication date: March 7, 2024
    Applicant: Apple Inc.
    Inventors: Mark B. Rober, Sawyer I. Cohen, Daniel Kurz, Tobias Holl, Benjamin B. Lyon, Peter Georg Meier, Jeffrey M. Riepling, Holly Gerhard
  • Patent number: 11715617
    Abstract: Some embodiments of the present disclosure provide a method that includes colliding a laser with an electron beam to produce backscattered x-rays while the electron beam is traversing a circular arc. This backscattering process is inverse Compton scattering (ICS). ICS x-rays are emitted in the same direction as the electrons. Because this ICS direction is changing as a function of time, the position of the x-ray beam on a detector will change depending on the timing of electron/laser collision. This position change is easily detected and converted to a timing measurement sensitive at the femtosecond scale, converting a very difficult timing measurement of laser pulse, electron pulse, and x-ray pulse synchronization into a simple and robust position measurement.
    Type: Grant
    Filed: August 20, 2021
    Date of Patent: August 1, 2023
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: William Graves, Mark Holl
  • Publication number: 20210384001
    Abstract: Some embodiments of the present disclosure provide a method that includes colliding a laser with an electron beam to produce backscattered x-rays while the electron beam is traversing a circular arc. This backscattering process is inverse Compton scattering (ICS). ICS x-rays are emitted in the same direction as the electrons. Because this ICS direction is changing as a function of time, the position of the x-ray beam on a detector will change depending on the timing of electron/laser collision. This position change is easily detected and converted to a timing measurement sensitive at the femtosecond scale, converting a very difficult timing measurement of laser pulse, electron pulse, and x-ray pulse synchronization into a simple and robust position measurement.
    Type: Application
    Filed: August 20, 2021
    Publication date: December 9, 2021
    Inventors: William Graves, Mark Holl
  • Patent number: 8748192
    Abstract: The present invention relates to an optical fluorescence dual sensor comprising a probe for sensing pH, a probe for sensing oxygen, an intra-reference probe and a matrix. The present invention also relates to methods of preparing an optical fluorescence dual sensor and methods of using them.
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: June 10, 2014
    Assignee: Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University
    Inventors: Yanqing Tian, Weiwen Zhang, Deirdre Meldrum, Hongguang Lu, Yuguang Jin, Mark Holl
  • Publication number: 20120145092
    Abstract: Methods are provided for determining whether or not a horse is genetically normal, is a carrier of, or is affected with or predisposed to Congenital Stationary Night Blindness and/or leopard complex spotting. The method is based on detection of an insertion in an intron in the horse Transient Receptor Potential Cation Channel, Subfamily M, Member 1 (TRPM1) gene.
    Type: Application
    Filed: December 5, 2011
    Publication date: June 14, 2012
    Inventors: Rebecca Bellone, Heather Mark Holl, Samantha Ann Brooks, George Forsyth
  • Publication number: 20120138469
    Abstract: Devices and methods are provided for separation of particles of a first selected electrophoretic mobility or isoelectric point from a fluid comprising particles of at least one other selected electrophoretic mobility or isoelectric point. The devices comprise a microchannel; electrodes to either side of the microchannel for applying a selected voltage to produce an electrical field across the microchannel orthogonal to the length of the microchannel; and outlets in said microchannel placed to receive outlet portions of the fluid containing enhanced concentrations of each type of particle. The devices may be used for particle detection, quantification, separation, mixing, dilution and concentration; to release, separate and detect interior particles of cells or organisms, and to separate particles such as proteins and microorganisms from biological fluids such as blood; or to separate and detect airborne contaminants such as bacterial warfare agents from air.
    Type: Application
    Filed: November 13, 2007
    Publication date: June 7, 2012
    Applicant: University of Washington
    Inventors: Paul Yager, Mark Holl, Darrel J. Bell, James Brody, Catherine R. Cabrera, Andrew E. Kamholz, Katerina Macounova, Dong Qin
  • Publication number: 20110275117
    Abstract: Systems and methods for growing photosynthetic cells that may be used to produce a biomass. The systems and methods recycle liquid and can produce a high cell concentration harvested biomass.
    Type: Application
    Filed: October 6, 2009
    Publication date: November 10, 2011
    Applicant: ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZ ONA STATE UNIVERSITY
    Inventors: Bruce E. Rittman, Chao Zhou, Raveender Vannela, Mark Holl, Jeff Houkal, Rhett Martineau
  • Publication number: 20070031819
    Abstract: Disclosed herein are systems, components, devices and methods for automated yeast pedigree analysis. Systems, components, devices and methods for analyzing microorganisms, cells, particles and molecules are also disclosed.
    Type: Application
    Filed: April 26, 2006
    Publication date: February 8, 2007
    Applicants: University of Washington, Fred Hutchinson Cancer Research Center
    Inventors: John Koschwanez, Mark Holl, Robert Carlson, Michael McMurray, Daniel Gottschling, Deirdre Meldrum
  • Publication number: 20060127275
    Abstract: The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of particle capture regions. The storage channel is preferably an isotropic spatially periodic channel. Sedimented particles can be resuspended following storage. This invention further provides a microfluidic analysis cartridge having a convoluted storage channel therein. The sample analysis can use optical, electrical, pressure sensitive, or flow sensitive detection. A plurality of analysis channels can be included in a single cartridge. The analysis channels can be joined to reagent inlets for diluents, indicators or lysing agents. A mixing channel can be positioned between the reagent inlet and the analysis region to allow mixing and reaction of the reagent. The cartridge can include additional valves and pumps for flow management.
    Type: Application
    Filed: August 2, 2005
    Publication date: June 15, 2006
    Applicant: University of Washington
    Inventors: Mark Holl, Floyd Edwards, Robert Morff, Gerald Klein
  • Publication number: 20050070944
    Abstract: A rotor (14) is located within a rotor chamber (12) formed in a housing (24). A drive shaft (16) extends from a motor and couples to the drive shaft interconnect (46) at the center of the rotor (14). One side of the rotor (14) is provided with circumferentially spaced apart radial rows of mincing edges (20). These edges (20) are situated on concentric circles or on a spiral. They are elongated circumferentially and may be situated substantially on an arc and substantially on an arc or on a chord. During use, the rotor (14) is rotated after biopsy obtained tissue (10) has been placed in the rotor chamber (12) on the side of the rotor (14) that includes the mincing edges (20). A fluid is delivered into and out from the rotor chamber (12) as the rotor (14) is being rotated to mince the biopsy, lyse the cells, and release the cell nuclei from the obtained tissue. Cell nuclei are expelled from the chamber (12) and are moved through a filter (58).
    Type: Application
    Filed: May 14, 2004
    Publication date: March 31, 2005
    Inventors: Mark Holl, Andrew Miller, Matthew Stanton, Carissa Sanchez, Thomas Paulson, Brian Reid, Deirdre Meldrum
  • Publication number: 20040256230
    Abstract: Devices and methods are provided for separation of particles of a first selected electrophoretic mobility or isoelectric point from a fluid comprising particles of at least one other selected electrophoretic mobility or isoelectric point. The devices comprise a microchannel comprising an inlet for introducing the fluid into the microchannel; electrodes to either side of the microchannel for applying a selected voltage to produce an electrical field across the microchannel orthogonal to the length of the microchannel; and outlets in said microchannel placed to receive outlet portions of the fluid containing enhanced concentrations of each type of particle. The devices may be used for particle detection, quantification, separation, mixing, dilution and concentration. Electrophoretic tags may be used to provide particles with altered electrophoretic mobilities and/or isoelectric points. Interior particles of cells or organisms may be released, separated and detected by these devices and methods.
    Type: Application
    Filed: February 27, 2004
    Publication date: December 23, 2004
    Applicant: University of Washington
    Inventors: Paul Yager, Mark Holl, Darrel J. Bell, James Brody, Catherine R. Cabrera, Andrew E. Kamholz, Katerina Macounova, Dong Qin