Patents by Inventor Mark Holmes

Mark Holmes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6762569
    Abstract: A method and apparatus for controlling the operation of a gas discharge including regulation of power provided to the lamp for maintaining constant light output throughout the lamp's life. A circuit is provided that continuously monitors the lamp voltage and current. A lamp resistance is determined by dividing the lamp voltage with the lamp current. Based on the lamp resistance, the power provided to the lamp is adjusted to maintain constant light output from the lamp.
    Type: Grant
    Filed: January 10, 2003
    Date of Patent: July 13, 2004
    Assignee: Henkel Corporation
    Inventors: Mark Holmes, Ronald E. Belek
  • Publication number: 20040111913
    Abstract: An electromagnetic energy spot curing system is provided which utilizes a template which moves relative to a source of radiation in the electromagnetic spectrum, such as an ultraviolet (UV) lamp. A channel is formed through the template of varying widths so that during the course of relative movement, different intensities of radiation emanating from the source is continuously passed through the channel and applied to a desired location, typically a curable material.
    Type: Application
    Filed: September 29, 2003
    Publication date: June 17, 2004
    Inventor: Mark Holmes
  • Publication number: 20040107880
    Abstract: A Conveyorable Plastic Thermoformed Pallet, having a support member and support legs with outer walls, internal walls and inner walls, is utilized to transport product on a conveyor system. The Pallet is made using a twin-sheet thermoforming process that requires two molds for an upper sheet of thermoplastic material and a lower sheet of thermoplastic material. The upper sheet forms a top deck of the support member and the internal walls of the support legs. The lower sheet forms the underside of the support member, the inner walls of the support legs, and leg bottoms. Both sheets are fused to form the twin-sheet outer walls. The upper sheet also forms web strips which stabilize the walls of the support legs and prevent deflection of the walls.
    Type: Application
    Filed: December 10, 2002
    Publication date: June 10, 2004
    Inventors: Cory D. Greene, Mark A. Holmes
  • Publication number: 20040094727
    Abstract: A UV spot curing lamp assembly comprises an integral filter support and shutter stop mechanism. The assembly includes a UV lamp and a light guide spaced therefrom for receiving filtered light from the lamp and for directing light through the light guide to a selected target or work site for curing materials thereat. A filter plate in the form of a borosilicate glass, having a selected thickness for the particular application, is disposed in relatively close proximity to the entrance surface of the light guide. A movable shutter plate, having an opening therethrough, is disposed between the filter and the light guide entrance surface. The shutter is movable from a first position wherein the opening is in registry with the light guide entrance surface to receive light from the lamp to a second position wherein a solid portion of the shutter plate blocks light from being received by the light guide entrance surface.
    Type: Application
    Filed: August 25, 2003
    Publication date: May 20, 2004
    Inventor: Mark Holmes
  • Patent number: 6520663
    Abstract: A UV curing lamp assembly permits adjustable positioning of a UV curing lamp with respect to a bracket supporting a reflector. The assembly includes an elongate UV lamp having opposed ends. A reflector having a central base and a curved reflective wall includes a pair of opposed openings through the reflector wall for passage of the UV lamp therethough. A bracket adjustably supports the reflector and the lamp. The bracket includes a bracket body movably supporting a mounting member for adjustably supporting the reflector with respect to the bracket body. A support arm extends from the bracket body towards one of the openings in the reflector. The support arm adjustably supports one of the ends of the UV lamp with respect to the reflector.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: February 18, 2003
    Assignee: Henkel Loctite Corporation
    Inventors: Mark Holmes, John P. Breault
  • Patent number: 6498165
    Abstract: Pyrimidine compounds (Formula I), or their pharmaceutically acceptable salts, hydrates, solvates, crystal forms and individual diastereomers, and pharmaceutical compositions including the same, which are inhibitors of tyrosine kinase enzymes, and as such are useful in the prophylaxis and treatment of protein tyrosine kinase-associated disorders, such as immune diseases, hyperproliferative disorders and other diseases in which inappropriate protein kinase action is believed to play a role, such as cancer, angiogensis, atheroscelerosis, graft rejection, rheumatoid arthritis and psoriasis.
    Type: Grant
    Filed: June 26, 2000
    Date of Patent: December 24, 2002
    Assignee: Merck & Co., Inc.
    Inventors: Helen M. Armstrong, Richard Beresis, Joung L. Goulet, Mark A. Holmes, Xingfang Hong, Sander G. Mills, William H. Parsons, Peter J. Sinclair, Mark G. Steiner, Frederick Wong, Dennis M. Zaller
  • Patent number: 6329380
    Abstract: Pyrimidine compounds (Formula I), or their pharmaceutically acceptable salts, hydrates, solvates, crystal forms and individual diastereomers, and pharmaceutical compositions including the same, which are inhibitors of tyrosine kinase enzymes, and as such are useful in the prophylaxis and treatment of proteins tyrosine kinase-associated disorders, such as immune diseases, hyperproliferative disorders and other diseases in which inappropriate protein kinase action is believed to play a role, such as cancer, angiogensis, atheroscelerosis, graft rejection, rheumatoid arthritis and psoriasis.
    Type: Grant
    Filed: June 26, 2000
    Date of Patent: December 11, 2001
    Assignee: Merck & Co., Inc.
    Inventors: Joung L. Goulet, Mark A. Holmes, Julianne A. Hunt, Sander G. Mills, William H. Parsons, Peter J. Sinclair, Dennis M. Zaller
  • Patent number: 5979704
    Abstract: A dispensing system detects system blockages in a delivery system due to curing or pack-out between a fluid source and a fluid dispense valve. The dispensing system automatically compensates for blockages in the delivery system by diverting fluid flow from one fluid circuit line to a parallel fluid circuit line leading to a dispensing valve.
    Type: Grant
    Filed: September 3, 1997
    Date of Patent: November 9, 1999
    Assignee: Loctite Corporation
    Inventors: Mark Holmes, Ronald E. Belek
  • Patent number: 5887853
    Abstract: A minimal wear valve assembly which includes a fluid reservoir having an inlet port and an outlet port for passage of the fluid therethrough. The reservoir defines a valve seat about and downstream of the outlet port. The assembly includes a valve having a first substantially non-deformable valve surface. The valve is movable with respect to the valve seat from an open condition which permits flow of the fluid through the outlet port to a closed condition which prevents flow of the fluid through the outlet port. The valve supports a sealing member for movement with the valve. The sealing member has greater compressibility than the first valve surface and provides a seal between the first valve surface and the valve seat upon movement of the valve to the closed condition.
    Type: Grant
    Filed: June 5, 1997
    Date of Patent: March 30, 1999
    Assignee: Loctite Corporation
    Inventors: Mark Holmes, John P. Breault
  • Patent number: 5880280
    Abstract: Aryl, alkyl, alkenyl and alkynyl macrolides of the general structural Formula I: ##STR1## have been prepared from suitable precursors by modification at C-30, C-33, and/or C-34 of the cyclohexyl ring. These macrolide immunosuppressants are useful in a mammalian host for the treatment of autoimmune diseases, infectious diseases and/or the prevention of rejection of foreign organ transplants and/or related afflictions, diseases and illnesses.
    Type: Grant
    Filed: June 15, 1994
    Date of Patent: March 9, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Helen M. Organ, Mark A. Holmes
  • Patent number: 5284877
    Abstract: Alkyl and alkenyl macrolides of the general structural Formula I: ##STR1## have been prepared from suitable precursors by oxidation and derivitization at C-17. These macrolide immunosuppressants are useful in a mammalian host for the treatment of autoimmune diseases, infectious diseases and/or the prevention of rejection of foreign organ transplants. In addition, these macrolide immunosuppressants are useful in the topical treatment of inflammatory and hyperproliferative skin diseases and cutaneous manifestations of immunologically-mediated illnesses.
    Type: Grant
    Filed: June 12, 1992
    Date of Patent: February 8, 1994
    Assignee: Merck & Co., Inc.
    Inventors: Helen M. Organ, Mark A. Holmes, Judith M. Pisano, Matthew J. Wyvratt
  • Patent number: 5277342
    Abstract: A dispensing apparatus capable of dispensing a wide variety of fluids, such as adhesives, is provided. The structure of the apparatus allows it to be miniaturized, thereby facilitating its use for many applications. The apparatus includes a cylindrical housing in which a slide is mounted. The housing includes a fluid reservoir which is supplied with pressurized fluid. A longitudinal passage extends through the slide for providing this fluid to the reservoir. A bellow seal is employed for sealing off an actuating mechanism from the reservoir. The seal is connected between the slide and a support fixedly mounted to the housing. A valve mechanism is provided at one end of the housing for controlling the flow of fluid from the reservoir. The valve mechanism is directly or indirectly responsive to the slide. Fluid may be caused to flow through the valve mechanism either by fluid pressure or by positive displacement.
    Type: Grant
    Filed: December 11, 1992
    Date of Patent: January 11, 1994
    Assignee: Loctite Corporation
    Inventors: Ewald F. Dickau, Mark Holmes
  • Patent number: 4855002
    Abstract: Polymerizable acrylic monomer adhesive systems comprising thirty to eighty percent by weight powdered aluminum filler material are disclosed. More specifically, the adhesive compositions comprise at least one polymerizable acrylate monomer system; an effective amount for initiation of a free radical initiator; and elemental (atomized) aluminum metal powder or powdered alumina.
    Type: Grant
    Filed: January 13, 1989
    Date of Patent: August 8, 1989
    Assignee: Loctite Corporation
    Inventors: David J. Dunn, Patrick P. Vano, James P. Moran, Jr., Mark Holmes, Elliott Frauenglass
  • Patent number: 4850995
    Abstract: Returning red blood cells to a patient after a centrifuge separation procedure by connecting an inflow line of a separation channel to an outflow line to provide a closed loop and recirculating liquid through it to remove blood cells. Also disclosed is pulling more liquid out of a flexible separation channel than permitted into it in order to reduce the volume of liquid to be used in returning cells to the patient.
    Type: Grant
    Filed: August 19, 1987
    Date of Patent: July 25, 1989
    Assignee: Cobe Laboratories, Inc.
    Inventors: Thomas K. Tie, Mark A. Holmes, Anne W. Rank
  • Patent number: 4722960
    Abstract: Polymerizable acrylic monomer adhesive systems comprising thirty to eighty percent by weight powdered aluminum filler material are disclosed. More specifically, the adhesive compositions comprise at least one polymerizable acrylate monomer system; an effective amount for initiation of a free radical initiator; and elemental (atomized) aluminum metal powder or powdered alumina.
    Type: Grant
    Filed: January 18, 1983
    Date of Patent: February 2, 1988
    Assignee: Loctite Corporation
    Inventors: David J. Dunn, Patrick P. Vano, James P. Moran, Jr., Mark Holmes, Elliott Frauenglass
  • Patent number: 4685900
    Abstract: A therapeutic device for removing pathological effectors brom body fluids of a patient is disclosed. Said device includes a chamber for receiving the body fluids and positioned within the chamber is a biospecific polymer. Said biospecific polymer interacts with and binds specific pathological effectors carried by the body fluid that is passed through the chamber.
    Type: Grant
    Filed: December 18, 1985
    Date of Patent: August 11, 1987
    Assignee: BioSpecific Technologies, Inc.
    Inventors: Mark R. Honard, Mark A. Holmes, Robert D. Jarrett
  • Patent number: 4574138
    Abstract: Rapid cure polymerizable monomer sealing and bonding compositions are disclosed. The polymerizable compositions comprise at least one polymerizable acrylate monomer system comprising a urethane acrylate monomer having vinyl reactive ends, and at least one hydroxy-terminated, monofunctional, short chain monomer which is soluble in or miscible with the urethane acrylate monomer; an effective amount for initiation of a free radical initiator; and a compatible filler material.
    Type: Grant
    Filed: January 9, 1984
    Date of Patent: March 4, 1986
    Inventors: James P. Moran, Jr., Mark Holmes
  • Patent number: 4409111
    Abstract: A preapplied, non-migratory, anti-galling composition, capable of retaining excellent lubricating properties up to temperatures of about 1200.degree. F. for an extended period of time, comprising an aqueous dispersion of graphite powder or metal powder, or both, in a polymeric binder. The composition is especially useful for providing a lubricating agent for metallic threaded objects to be subjected to high temperatures.
    Type: Grant
    Filed: April 12, 1982
    Date of Patent: October 11, 1983
    Assignee: Loctite Corporation
    Inventors: Mark Holmes, Elliott Frauenglass