Patents by Inventor Mark J. Roth

Mark J. Roth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of diagnosing and treating cancer using B-catenin splice variants
    Patent number: 10000813
    Abstract: The invention relates to method and compositions for treating and diagnosing cancer, in particular ?-catenin related cancers. In general, the methods include administering RNAi constructs. The invention further relates to methods of identifying CTNNB1 related cancer therapeutics.
    Type: Grant
    Filed: January 3, 2012
    Date of Patent: June 19, 2018
    Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Mark J. Roth, Konrad Huppi
  • METHOD OF DIAGNOSING AND TREATING CANCER USING B-CATENIN SPLICE VARIANTS
    Publication number: 20120294929
    Abstract: The invention relates to method and compositions for treating and diagnosing cancer, in particular ?-catenin related cancers. In general, the methods include administering RNAi constructs. The invention further relates to methods of identifying CTNNB1 related cancer therapeutics.
    Type: Application
    Filed: January 3, 2012
    Publication date: November 22, 2012
    Applicant: Health & Human Services - NIH
    Inventors: Mark J. Roth, Konrad Huppi
  • Method of diagnosing and treating cancer using B-catenin splice variants
    Patent number: 8110352
    Abstract: The invention relates to method of diagnosing and treating cancer, in particular ?-catenin related cancers. The invention further relates to methods of identifying CTNNB1 related cancer CTNNB1 therapeutics.
    Type: Grant
    Filed: February 10, 2006
    Date of Patent: February 7, 2012
    Assignee: The United States of America as represented by the Secretary, Department of Health & Human Services
    Inventors: Mark J. Roth, Konrad Huppi
  • METHOD OF DIAGNOSING AND TREATING CANCER USING B-CATENIN SPLICE VARIANTS
    Publication number: 20090111762
    Abstract: The invention relates to method of diagnosing and treating cancer, in particular ?-catenin related cancers. The invention further relates to methods of identifying CTNNB1 related cancer CTNNB1 therapeutics.
    Type: Application
    Filed: February 10, 2006
    Publication date: April 30, 2009
    Applicant: Govt. of the US, as represented by the Secretary, Department of Health and Human Services
    Inventors: Mark J. Roth, Konrad Huppi
  • Isolation of cellular material under microscopic visualization using an adhesive/extraction reagent tipped probe
    Patent number: 5843644
    Abstract: A method of direct extraction of cellular material from a tissue sample which involves: forming an image field of cells of the tissue sample utilizing a microscope, identifying at least one zone of cells of interest from the image field of cells which at least one zone of cells of interest includes different types of cells than adjacent zones of cells, and extracting the at least one zone of cells of interest from the tissue sample. The extracted zone(s) of cells is subjected to analysis. The overall process of identifying, extracting, transporting, and analyzing the extracted zones(s) of cells can be fully automated.
    Type: Grant
    Filed: March 1, 1994
    Date of Patent: December 1, 1998
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Lance A. Liotta, Zhengping Zhuang, Michael R. Buck, William G. Stetler-Stevenson, Irina A. Lubensky, Mark J. Roth