Patents by Inventor Mark J. Schulz

Mark J. Schulz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11730857
    Abstract: A biomedical implant (16, 18) is formed from magnesium (Mg) single crystal (10). The biomedical implant (16, 18) may be biodegradable. The biomedical implant (16, 18) may be post treated to control the mechanical properties and/or corrosion rate thereof said Mg single crystal (10) without changing the chemical composition thereof. A method of making a Mg single crystal (10) for biomedical applications includes filling a single crucible (12) with more than one chamber with polycrystalline Mg, melting at least a portion of said polycrystalline Mg, and forming more than one Mg single crystal (10) using directional solidification.
    Type: Grant
    Filed: March 9, 2021
    Date of Patent: August 22, 2023
    Assignee: University of Cincinnati
    Inventors: Vesselin N. Shanov, Vibhor Chaswal, Pravahan Salunke, Madhura Joshi, Guangqi Zhang, Mark J. Schulz, Sergey N. Yarmolenko, Doug Nienaber
  • Patent number: 11542635
    Abstract: Carbon nanotube (CNT) fiber and sheets formed by a specialized gas assembly pyrolytic reactor method that permits gas phase integration of nano and micro particles (NMPs) are processed into yarn and fabric used in the manufacture of personal protective clothing and equipment that can be tailored via selection of NMPs for a wide variety of functionality depending on target application. The CNT-NMP hybrid fabrics may be designed to exhibit enhanced electrical and thermal conductivity, moisture wicking, air filtering, and environmental sensing properties.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: January 3, 2023
    Assignee: UNIVERSITY OF CINCINNATI
    Inventors: Mark J. Schulz, Sathya Kanakaraj, David Mast, Vesselin Shanov, Devika Chauhan, Guangfeng Hou, Vianessa Ng, Chenhao Xu, Rui Daniel Chen, Ashley Kubley, Xiaoda Hou, Richard Kleismit, Zhangzhang Yin
  • Patent number: 11377440
    Abstract: Disclosed are compounds having the formula: (I) wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, R17, Rx, and Ry are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: July 5, 2022
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: David T. Fosbenner, Todd L. Graybill, Jianxing Kang, Bryan W. King, Yunfeng Lan, Lara Kathryn Leister, Mukesh K. Mahajan, John F. Mehlmann, Angel I. Morales-Ramos, George Scott Pesiridis, Joshi M. Ramanjulu, Joseph J. Romano, Stuart Paul Romeril, Mark J. Schulz, Huiqiang Zhou, Junya Qu
  • Publication number: 20210196854
    Abstract: A biomedical implant (16, 18) is formed from magnesium (Mg) single crystal (10). The biomedical implant (16, 18) may be biodegradable. The biomedical implant (16, 18) may be post treated to control the mechanical properties and/or corrosion rate thereof said Mg single crystal (10) without changing the chemical composition thereof. A method of making a Mg single crystal (10) for biomedical applications includes filling a single crucible (12) with more than one chamber with polycrystalline Mg, melting at least a portion of said polycrystalline Mg, and forming more than one Mg single crystal (10) using directional solidification.
    Type: Application
    Filed: March 9, 2021
    Publication date: July 1, 2021
    Inventors: Vesselin N. Shanov, Vibhor Chaswal, Pravahan Salunke, Madhura Joshi, Guangqi Zhang, Mark J. Schulz, Sergey N. Yarmolenko, Doug Nienaber
  • Publication number: 20200291001
    Abstract: Disclosed are compounds having the formula: (I) wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, R17, Rx, and Ry are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.
    Type: Application
    Filed: October 4, 2018
    Publication date: September 17, 2020
    Inventors: David T. FOSBENNER, Todd L. GRAYBILL, Jianxing KANG, Bryan W. KING, Yunfeng LAN, Lara Kathryn LEISTER, Mukesh K. MAHAJAN, John F. MEHLMANN, Angel I. MORALES-RAMOS, George Scott PESIRIDIS, Joshi M. RAMANJULU, Joseph J. ROMANO, Stuart Paul ROMERIL, Mark J. SCHULZ, Huiqiang ZHOU, Junya QU
  • Publication number: 20200270774
    Abstract: Carbon nanotube (CNT) fiber and sheets formed by a specialized gas assembly pyrolytic reactor method that permits gas phase integration of nano and micro particles (NMPs) are processed into yarn and fabric used in the manufacture of personal protective clothing and equipment that can be tailored via selection of NMPs for a wide variety of functionality depending on target application. The CNT-NMP hybrid fabrics may be designed to exhibit enhanced electrical and thermal conductivity, moisture wicking, air filtering, and environmental sensing properties.
    Type: Application
    Filed: July 10, 2018
    Publication date: August 27, 2020
    Inventors: Mark J. Schulz, Sathya Kanakaraj, David Mast, Vesselin Shanov, Devika Chauhan, Guangfeng Hou, Vianessa Ng, Chenhao Xu, Rui Daniel Chen, Ashley Kubley, Xiaoda Hou, Richard Kleismit
  • Patent number: 10265205
    Abstract: Methods for making a magnesium biodegradable stent for medical implant applications, using magnesium foil or pure magnesium or magnesium alloys that are biodegradable and performing a lithographic technique to configure the features and dimensions of the magnesium foil, and rolling the magnesium foil to form a cylinder.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: April 23, 2019
    Assignee: UNIVERSITY OF CINCINNATI
    Inventors: Vesselin N. Shanov, Prabir Roy-Chaudhury, Mark J. Schulz, Zhangzhang Yin, Begona Campos-Naciff, Yang Wang
  • Patent number: 9845243
    Abstract: A method of forming a carbon nanotube array substrate is disclosed. One embodiment comprises depositing a composite catalyst layer on the substrate, oxidizing the composite catalyst layer, reducing the oxidized composite catalyst layer, and growing the array on the composite catalyst layer. The composite catalyst layer may comprise a group VIII element and a non-catalytic element deposited onto the substrate from an alloy. In another embodiment, the composite catalyst layer comprises alternating layers of iron and a lanthanide, preferably gadolinium or lanthanum. The composite catalyst layer may be reused to grow multiple carbon nanotube arrays without additional processing of the substrate. The method may comprise bulk synthesis by forming carbon nanotubes on a plurality of particulate substrates having a composite catalyst layer comprising the group VIII element and the non-catalytic element. In another embodiment, the composite catalyst layer is deposited on both sides of the substrate.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: December 19, 2017
    Inventors: Vesselin N. Shanov, Andrew Gorton, Yeo-Heung Yun, Mark J. Schulz
  • Patent number: 9796121
    Abstract: A method of forming an array of aligned, uniform-length carbon nanotubes on a planar surface of a substrate employing a composite catalyst layer of iron and cobalt. The carbon nanotubes have visible length and are useful for producing spun threads of carbon nanotubes having improved spinability and mechanical and electrical properties.
    Type: Grant
    Filed: April 26, 2013
    Date of Patent: October 24, 2017
    Assignee: University of Cincinnati
    Inventors: Vesselin N. Shanov, Mark J. Schulz
  • Publication number: 20170281377
    Abstract: Methods for making a magnesium biodegradable stent for medical implant applications, using magnesium foil or pure magnesium or magnesium alloys that are biodegradable and performing a lithographic technique to configure the features and dimensions of the magnesium foil, and rolling the magnesium foil to form a cylinder.
    Type: Application
    Filed: April 25, 2017
    Publication date: October 5, 2017
    Applicant: UNIVERSITY OF CINCINNATI
    Inventors: VESSELIN N. SHANOV, PRABIR ROY-CHAUDHURY, MARK J. SCHULZ, ZHANGZHANG YIN, BEGONA CAMPOS-NACIFF, YANG WANG
  • Publication number: 20170239386
    Abstract: A biomedical implant (16, 18) is formed from magnesium (Mg) single crystal (10). The biomedical implant (16, 18) may be biodegradable. The biomedical implant (16, 18) may be post treated to control the mechanical properties and/or corrosion rate thereof said Mg single crystal (10) without changing the chemical composition thereof. A method of making a Mg single crystal (10) for biomedical applications includes filling a single crucible (12) with more than one chamber with polycrystalline Mg, melting at least a portion of said polycrystalline Mg, and forming more than one Mg single crystal (10) using directional solidification.
    Type: Application
    Filed: August 18, 2015
    Publication date: August 24, 2017
    Inventors: Vesselin N. Shanov, Vibhor Chaswal, Pravahan Salunke, Madhura Joshi, Guangqi Zhang, Mark J. Schulz, Sergey N. Yarmolenko, Doug Nienaber
  • Patent number: 9655752
    Abstract: Methods for making a magnesium biodegradable stent for medical implant applications, using magnesium foil or pure magnesium or magnesium alloys that are biodegradable and performing a lithographic technique to configure the features and dimensions of the magnesium foil, and rolling the magnesium foil to form a cylinder.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 23, 2017
    Assignee: University of Cincinnati
    Inventors: Vesselin N. Shanov, Prabir Roy-Chaudhury, Mark J. Schulz, Zhangzhang Yin, Begona Campos-Naciff, Yang Wang
  • Publication number: 20150137414
    Abstract: A method of forming an array of aligned, uniform-length carbon nanotubes on a planar surface of a substrate employing a composite catalyst layer of iron and cobalt. The carbon nanotubes have visible length and are useful for producing spun threads of carbon nanotubes having improved spinability and mechanical and electrical properties.
    Type: Application
    Filed: April 26, 2013
    Publication date: May 21, 2015
    Inventors: Vesselin N. Shanov, Mark J. Schulz
  • Publication number: 20150105854
    Abstract: Methods for making a magnesium biodegradable stent for medical implant applications, using magnesium foil or pure magnesium or magnesium alloys that are biodegradable and performing a lithographic technique to configure the features and dimensions of the magnesium foil, and rolling the magnesium foil to form a cylinder.
    Type: Application
    Filed: March 15, 2013
    Publication date: April 16, 2015
    Inventors: Vesselin N. Shanov, Prabir Roy-Chaudhury, Mark J. Schulz, Zhangzhang Yin, Begona Campos-Naciff, Yang Wang
  • Publication number: 20140295098
    Abstract: A method of forming a carbon nanotube array substrate is disclosed. One embodiment comprises depositing a composite catalyst layer on the substrate, oxidizing the composite catalyst layer, reducing the oxidized composite catalyst layer, and growing the array on the composite catalyst layer. The composite catalyst layer may comprise a group VIII element and a non-catalytic element deposited onto the substrate from an alloy. In another embodiment, the composite catalyst layer comprises alternating layers of iron and a lanthanide, preferably gadolinium or lanthanum. The composite catalyst layer may be reused to grow multiple carbon nanotube arrays without additional processing of the substrate. The method may comprise bulk synthesis by forming carbon nanotubes on a plurality of particulate substrates having a composite catalyst layer comprising the group VIII element and the non-catalytic element. In another embodiment, the composite catalyst layer is deposited on both sides of the substrate.
    Type: Application
    Filed: June 16, 2014
    Publication date: October 2, 2014
    Inventors: Vesselin N. SHANOV, Andrew Gorton, Yeo-Heung Yun, Mark J. Schulz
  • Patent number: 8753602
    Abstract: A method of forming a carbon nanotube array on a substrate is disclosed. One embodiment of the method comprises depositing a composite catalyst layer on the substrate, oxidizing the composite catalyst layer, reducing the oxidized composite catalyst layer, and growing the array on the composite catalyst layer. The composite catalyst layer may comprise a group VIII element and a non-catalytic element deposited onto the substrate from an alloy. In another embodiment, the composite catalyst layer comprises alternating layers of iron and a lanthanide, preferably gadolinium or lanthanum. The composite catalyst layer may be reused to grow multiple carbon nanotube arrays without additional processing of the substrate. The method may comprise bulk synthesis by forming carbon nanotubes on a plurality of particulate substrates having a composite catalyst layer comprising the group VIII element and the non-catalytic element. In another embodiment, the composite catalyst layer is deposited on both sides of the substrate.
    Type: Grant
    Filed: April 11, 2007
    Date of Patent: June 17, 2014
    Assignee: University of Cincinnati
    Inventors: Vesselin N. Shanov, Andrew Gorton, Yeo-Heung Yun, Mark J. Schulz
  • Publication number: 20140038968
    Abstract: The present invention relates to certain novel compounds of Formula (I): and methods for preparing these compounds, compositions, intermediates and derivatives thereof and for the treatment of prokineticin 1 or prokinetin 1 receptor mediated disorders.
    Type: Application
    Filed: October 17, 2012
    Publication date: February 6, 2014
    Inventors: Steven J. Coats, Alexey B. Dyatkin, Wei He, Joseph Lisko, Tamara A. Miskowski, Janet L. Ralbovsky, Mark J. Schulz
  • Publication number: 20130316172
    Abstract: A method using of electrostatic spraying or dispersing processes and techniques for depositing a particulate material onto the outside surfaces of carbon nanotubes (CNTs) and CNT elongates consisting of the CNTs. The particulate material can include either or both particles and droplets, and the material can be an element, compound or composition, including polymers and thermoplastics. The particulate material is dispersed and induced with a static charge, while the CNT elongate is grounded.
    Type: Application
    Filed: February 1, 2012
    Publication date: November 28, 2013
    Applicant: GENERAL NANO LLC
    Inventors: Vesselin N. Shanov, Mark J. Schulz, Gary Martin Conroy
  • Patent number: 8501937
    Abstract: The invention is directed to compounds and methods of synthesizing hydroxyethlamino amides and their use in treatment of aspartyl protease mediated diseases and conditions.
    Type: Grant
    Filed: March 28, 2012
    Date of Patent: August 6, 2013
    Assignee: Janssen Pharmaceutica, NV
    Inventors: Steven J. Coats, Dennis J. Hlasta, Mark J. Schulz
  • Patent number: 8383637
    Abstract: The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE.
    Type: Grant
    Filed: August 4, 2005
    Date of Patent: February 26, 2013
    Assignee: Jansssen Pharmaceutica N.V.
    Inventors: Ellen Baxter, Francois Paul Bischoff, Robert E. Boyd, Mirielle Braeken, Steve Coats, Yifang Huang, Alfonzo D. Jordan, Chi Luo, Marc Hubert Mercken, Serge Maria Aloysius Pieters, Allen B. Reitz, Charles H. Reynolds, Tina Morgan Ross, Brett A. Tounge, Mark J. Schulz, Hans Louis Jos De Winter