Abstract: Embodiments of a system and method of use for endoscope fluorescence inspection are generally described herein. In an example embodiment, a fluorescence inspection device provides capabilities for internal inspection of an endoscope lumen through a handheld unit coupled to a light pipe that identifies fluorescence from residual biological material exposed to a fluorescing agent. In another example embodiment, a fluorescence inspection device provides capabilities for external inspection of an endoscope surface through a handheld unit which emits excitation light and identifies fluorescence of residual biological material exposed to the fluorescing agent. The embodiments may also include an output device to output an indication in response to a detection (or lack of detection) of the fluorescent light with the fluorescence inspection device. Additional use examples and device structures are also described.

Abstract: The invention relates to a compound of formula (I): or pharmaceutically acceptable salts, solvates, tautomers, stereoisomers or mixtures thereof; wherein the fused ring moiety is a non-alkylating moiety; and wherein the compounds are useful as medicaments, in particular for use as a drug in an antibody-drug conjugate and in the treatment of a proliferative disease, a bacterial infection, a malarial infection and inflammation.

Abstract: The present application relate to crystalline azide compound of formula (II) which is used as an intermediate for the preparation of halichondrin B analogues such as eribulin or pharmaceutically acceptable salts thereof. The present application also covers purification process of azide compound of formula (II) and its further conversion to eribulin or a pharmaceutically acceptable salts thereof.

Abstract: A novel dent-puller assisting apparatus, system, and method are disclosed herein. The invention provides a stable anchor point for the attachment of a variety of mechanisms to be used in the process of straightening or repair of car body panels. The invention is designed to require a minimum number of parts and connections, be easy to install and operate, and have sufficient flexibility to accomplish the required ends.

Abstract: Systems, devices, and methods are described for wireless communication. In one example a first wireless signal is received in a first radio frequency spectrum using a first antenna exterior to a building. The first wireless signal is associated with a first wireless protocol. The first wireless signal is converted into a first intermediate signal associated with a coaxial protocol. The first intermediate signal is transmitted to an interior of the building using a coaxial cable. The first intermediate signal is converted into a second signal associated with a second wireless protocol. The second signal is then transmitted in a second radio frequency spectrum using a second antenna interior to the building. The second signal is transmitted using the second wireless protocol.

Abstract: Various embodiments of systems, devices, and methods are described for wireless communication. In one example a first wireless signal is received in a first radio frequency spectrum using a first antenna exterior to a building. The first wireless signal is associated with a first wireless protocol. The first wireless signal is converted into a first intermediate signal associated with a coaxial protocol. The first intermediate signal is transmitted to an interior of the building using a coaxial cable. The first intermediate signal is converted into a second signal associated with a second wireless protocol. The second signal is then transmitted in a second radio frequency spectrum using a second antenna interior to the building. The second signal is transmitted using the second wireless protocol.

Abstract: The present application relate to a purification process for preparation of halichondrin B analogues such as eribulin or pharmaceutically acceptable salts thereof having less than 0.15% or substantially free or free from one or more impurities. The present application also provide acid addition salts of eribulin and process for preparation thereof.

Abstract: Systems, devices, and methods are described for wireless communication. In one example a first wireless signal is received in a first radio frequency spectrum using a first antenna exterior to a building. The first wireless signal is associated with a first wireless protocol. The first wireless signal is converted into a first intermediate signal associated with a coaxial protocol. The first intermediate signal is transmitted to an interior of the building using a coaxial cable. The first intermediate signal is converted into a second signal associated with a second wireless protocol. The second signal is then transmitted in a second radio frequency spectrum using a second antenna interior to the building. The second signal is transmitted using the second wireless protocol.

Abstract: Microsclerotia of entomopathogenic fungi, including Metarhizium species, Beauveria species, and Lecanicillium species, may be produced. These microsclerotia are effective for the control of a wide variety of insect pests, particularly soil-dwelling insect pests.

Abstract: Disclosed are compounds comprising alkylating moieties, such as pyrrolobenzodiazepines (PBDs, comprising three fused 6-7-5-membered rings), C2-substituted PBDs (including C2-endo, C1/C2-endo, and C2/C3-endo PBDs), pyrridinobenzodiazepines (PDDs, comprising three fused 6-7-6-membered rings), indolinobenzodiazapenes (IBDs, comprising four fused 6-7-5-6 membered rings), and tetrahydroisoquinolinebenzodiazapines (QBDs, comprising four fused 6-7-6-6 membered rings), or a pharmaceutically acceptable salt thereof. In particular, the disclosed compounds, or a pharmaceutically acceptable salt thereof, may comprise a guanine alkylating moiety linked to an aromatic group. The disclosed compounds are useful as medicaments, in particular as anti-proliferative agents.

Abstract: Various embodiments of systems, devices, and methods are described for wireless communication. In one example a first wireless signal is received in a first radio frequency spectrum using a first antenna exterior to a building. The first wireless signal is associated with a first wireless protocol. The first wireless signal is converted into a first intermediate signal associated with a coaxial protocol. The first intermediate signal is transmitted to an interior of the building using a coaxial cable. The first intermediate signal is converted into a second signal associated with a second wireless protocol. The second signal is then transmitted in a second radio frequency spectrum using a second antenna interior to the building. The second signal is transmitted using the second wireless protocol.

Abstract: An apparatus for use in a method of decontaminating a device including a tray. A membrane permeable by a decontaminating fluid is positioned over the top of the tray to form an enclosed space. A lid is secured to the tray and the membrane is positioned between the tray and the lid. A hub assembly is positioned within the tray.

Abstract: The invention relates to a compound of formula (I) or formula (II) or pharmaceutically acceptable salts, solvates, tautomers, stereoisomers or mixtures thereof; which are useful as medicaments, in particular as anti-proliferative agents and for use as a drug in an antibody-drug conjugate and in the treatment of proliferative diseases.

Abstract: The invention relates to pyrridinobenzodiazepines (PDDs) comprising three fused 6-7-6-membered rings linked to aromatic groups, and pharmaceutically acceptable salts thereof, which are useful as medicaments, in particular as anti-proliferative agents. PDDs may be represented by formula (I) and pharmaceutically acceptable salts thereof.

Abstract: The invention relates to compounds comprising a substituted pyrrolo-, indolino- or tetrahydroisoquinoline-benzodiazepines alkylating moiety linked via the A-ring to aromatic groups of formula (Ia), and to pharmaceutically acceptable salts thereof, which are useful as medicaments, in particular as anti-proliferative agents.

Abstract: A method and decompression unit for performing decompression to determine image element values from compressed data representing a block of image element values each comprising one or more data values relating to a respective one or more channels. An indication of an origin value for each of the channels is read from the compressed data. For each of the channels, an indication of a first number of bits for representing difference values between the data values and the origin value for the channel is read from the compressed data. For each of the one or more channels, a second number of bits is obtained, wherein representations of the difference values for each of the channels are included in the compressed data using the second number of bits for that channel. The obtained second numbers of bits for the respective channels are used to read the representations of the difference values for the image element values being decompressed from the compressed data.

Abstract: A method and compression unit for compressing a block of image data to satisfy a target level of compression, wherein the block of image data comprises a plurality of image element values, each image element value comprising one or more data values relating to a respective channel. For each of the channels: (i) an origin value for the channel for the block is determined, (ii) difference values are determined representing differences between the data values and the determined origin value for the channel for the block, and (iii) a first number of bits for losslessly representing a maximum difference value of the difference values for the channel for the block is determined.

Abstract: Described herein is a method for blastospore-based insect control products of entomopathogenic fungi including either B. bassiana or I. fumosorosea that produces high concentrations of stable, effective spores by identifying nutritional and environmental conditions required for the rapid production of high concentrations of a stable and infective yeast-like blastospore composition.

Abstract: Various embodiments of systems, devices, and methods are described for wireless communication. In one example a first wireless signal is received in a first radio frequency spectrum using a first antenna exterior to a building. The first wireless signal is associated with a first wireless protocol. The first wireless signal is converted into a first intermediate signal associated with a coaxial protocol. The first intermediate signal is transmitted to an interior of the building using a coaxial cable. The first intermediate signal is converted into a second signal associated with a second wireless protocol. The second signal is then transmitted in a second radio frequency spectrum using a second antenna interior to the building. The second signal is transmitted using the second wireless protocol.