Patents by Inventor Mark James Bamford

Mark James Bamford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzazepine derivatives for the treatment of neurological disorders
    Patent number: 8207331
    Abstract: The present invention relates to novel benzazepine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: June 26, 2012
    Assignee: Glaxo Group Limited
    Inventors: Mark James Bamford, David Kenneth Dean, Sanjeet Singh Sehmi, David Matthew Wilson, Jason Witherington
  • Pyrazolo [3,4-D]azepine derivatives as histamine H3 antagonists
    Patent number: 7888347
    Abstract: The present invention relates to novel pyrazole derivatives of formula I having pharmacological activity as H3 antagonists processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Grant
    Filed: July 4, 2006
    Date of Patent: February 15, 2011
    Assignee: Glaxo Group Limited
    Inventors: Mark James Bamford, David Matthew Wilson
  • IMIDAZOPYRIDINE DERIVATIVES AS ACID PUMP ANTAGONISTS
    Publication number: 20100311740
    Abstract: This invention relates to newly identified imidazopyridine compounds of formula (I), to the use of such compounds in treating GERD and the like.
    Type: Application
    Filed: June 28, 2006
    Publication date: December 9, 2010
    Inventors: Mark James Bamford, Richard Leonard Elliott, Gerard Martin Paul Giblin, Antoinette Naylor, Terence Aaron Chal, Andrew Kenneth Takle, Jason Witherington
  • Benzazepine derivatives for the treatment of neurological disorders
    Patent number: 7799773
    Abstract: The present invention relates to novel benzazepine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: September 21, 2010
    Assignee: Glaxo Group Limited
    Inventors: Mark James Bamford, David Kenneth Dean, Sanjeet Singh Sehmi, David Matthew Wilson, Jason Witherington
  • Benzazepine Derivatives For The Treatment of Neurological Disorders
    Publication number: 20100145040
    Abstract: The present invention relates to novel benzazepine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Application
    Filed: February 17, 2010
    Publication date: June 10, 2010
    Inventors: Mark James Bamford, David Kenneth Dean, Sanjeet Singh Sehmi, David Matthew Wilson, Jason Witherington
  • BENZAZEPINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
    Publication number: 20090105226
    Abstract: The present invention relates to novel benzazepine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Application
    Filed: December 19, 2008
    Publication date: April 23, 2009
    Inventors: Mark James BAMFORD, David Kenneth Dean, Sanjeet Singh Sehmi, David Matthew Wilson, Jason Witherington
  • Pyridine derivatives as Raf kinase inhibitors
    Patent number: 7452906
    Abstract: Compounds and their use as pharmaceuticals particularly as Raf kinase inhibitors for the treatment of neurotraumatic diseases, cancer, chronic neurodegeneration, pain, migraine and cardiac hypertrophy.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: November 18, 2008
    Assignee: SmithKline Beecham P.L.C.
    Inventors: Mark James Bamford, David Kenneth Dean, Antoinette Naylor, Andrew Kenneth Takle, David Matthew Wilson
  • Piperazinone Derivatives Useful as Histamine H3 Receptor Antagonists and/or Inverse Agonists
    Publication number: 20080275027
    Abstract: The invention relates to compounds of formula (I) or salts and solvates thereof, processes for their preparation, to compositions containing them and to their use in the treatment of various disorders, such as allergic rhinitis: wherein R1 and R2 are as defined in the specification.
    Type: Application
    Filed: July 17, 2006
    Publication date: November 6, 2008
    Inventors: Rachael Ann Ancliff, Mark James Bamford, Simon Teanby Hodgson, Christopher Allan Parr, Panayiotic Alexandrou Procopiou, David Matthew Wilson, Michael Woodrow
  • Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases
    Publication number: 20080255358
    Abstract: Disclosed are imidazopyridine compounds having the formula:
    Type: Application
    Filed: March 22, 2006
    Publication date: October 16, 2008
    Inventors: Mark James Bamford, Emmanuel Hubert Demont, Richard Leonard Elliott, Gerard Martin Paul Giblin, Antoinette Naylor, Terence Aaron Panchal, Jason Witherington
  • 5-Acylamino-1,1?-biphenyl-4-carboxamide derivatives and their use as P38 kinase inhibitors
    Patent number: 7432289
    Abstract: Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: October 7, 2008
    Assignee: Glaxo Group Limited
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Stephen Sean Flack, Dramane Ibrahim Lainé, Suzanne Joy Merrick, Kathryn Jane Smith, Ann Louise Walker
  • Compounds
    Publication number: 20080207638
    Abstract: The present invention relates to compounds of formula (I), and salts thereof, processes for their preparation, to compositions containing them and to their use in the treatment of various disorders, such as allergic rhinitis.
    Type: Application
    Filed: July 17, 2006
    Publication date: August 28, 2008
    Inventors: Rachael Ann Ancliff, Mark James Bamford, Simon Teanby Hodgson, Christopher Allan Parr, Panayiotis Alexandrou Procopiou, David Matthew Wilson, Michael Woodrow
  • Pyrazolo [3,4-D]Azepine Derivatives as Histamine H3 Antagonists
    Publication number: 20080176832
    Abstract: The present invention relates to novel pyrazole derivatives of formula I having pharmacological activity as H3 antagonists processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Application
    Filed: July 4, 2006
    Publication date: July 24, 2008
    Inventors: Mark James Bamford, David Matthew Wilson
  • 5?-carbamoyl-1,1?-biphenyl-4-carboxamide derivatives and their use as p38 kinase inhibitors
    Patent number: 7396843
    Abstract: Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: July 8, 2008
    Assignee: Glaxo Group Limited
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Suzanne Joy Merrick, Ann Louise Walker
  • Imidazopyridine derivatives as kinase inhibitors
    Patent number: 7348339
    Abstract: A compound of the formula and physiologically acceptable salts and or N-oxides thereof wherein, X1 is N or CR3; X2 is N or CR4; X3 is N or CR5; X4 is N or CR6. with the proviso that at least one but not more than two of X1, X2, X3 and X4 represents N. R1 is a 5-, or 6-membered heterocyclic group selected from group a, b, c or d wherein X5 is a group selected from N or CR7 and X6 is a group selected from O, S or NR8; X7 and X8 which may be the same or different is a group selected from N or CR9; X9 is a group selected from O, S or NR8 and X10 is N or CR10; X11, X12 and X13 may be the same or different and selected from a group N or CR11; processes for their preparation, pharmaceutical compositions containing them and their use in medicine.
    Type: Grant
    Filed: March 21, 2003
    Date of Patent: March 25, 2008
    Assignee: Glaxo Group Limited
    Inventors: Nicholas Bailey, Mark James Bamford, Haifeng Cui, Stephen Garland, Krista B Goodman, Mark A Hilfiker, Dennis Lee, Terence Aaron Panchal, Robert A Stavenger, David Matthew Wilson, Jason Witherington
  • Biphenylcarboxylic amide derivatives as p38 kinase inhibitors
    Patent number: 7309800
    Abstract: Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: November 3, 2006
    Date of Patent: December 18, 2007
    Assignee: Glaxo Group Limited
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Stephen Sean Flack, Dramane Ibrahim Lainé, Ann Louise Walker
  • Nitrogen-containing heterocyclic compounds and their use as Raf inhibitors
    Patent number: 7297693
    Abstract: Compounds and their use as pharmaceuticals particularly as Raf kinase inhibitors for the treatment of neurotraumatic diseases, cancer, chronic neurodegeneration, pain, migraine and cardiac hypertrophy.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: November 20, 2007
    Assignee: SmithKline Beecham P.L.C.
    Inventors: Mark James Bamford, David Kenneth Dean, Antoinette Naylor, Andrew Kenneth Takle, David Matthew Wilson
  • Biphenyl-derivatives as p38-kinase inhibitors
    Patent number: 7183297
    Abstract: Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: February 27, 2007
    Assignee: Glaxo Group Limited
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Stephen Sean Flack, Dramane Ibrahim Lainé, Ann Louise Walker
  • Biphenylcarboxylic amide derivatives as p38-kinase inhibitors
    Patent number: 7151118
    Abstract: Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: December 19, 2006
    Assignee: Glaxo Group Limited
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Stephen Sean Flack, Dramane Ibrahim Lainé, Ann Louise Walker
  • Biphenyl-derivatives as p38-kinase inhibitors
    Publication number: 20040249161
    Abstract: Compounds of formula (I), or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Application
    Filed: April 15, 2004
    Publication date: December 9, 2004
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Stephen Sean Flack, Dramane Ibrahim Laine, Ann Louise Walker
  • 5-acylamino-1,1'-biphenyl-4-carboxamide derivatives and their use as p38 kinase inhibitors
    Publication number: 20040242868
    Abstract: Compounds of formula (I): 1
    Type: Application
    Filed: April 15, 2004
    Publication date: December 2, 2004
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerhill, Stephen Sean Flack, Dramane Ibrahim Laine, Suzanne Joy Merrick, Kathryn Jane Smith, Ann Louise Walker