Abstract: A plurality of chromatograms is run using a salt gradient with a range of constant pH values or using a pH gradient with a range of constant salt concentrations. A chromatography optimization algorithm can be used to identify at least one salt gradient chromatogram or at least one pH gradient chromatogram to establish optimized buffer conditions. The chromatography optimization algorithm can include a total number of peaks algorithm, a peak-to-valley algorithm, and/or a peak capacity algorithm.

Abstract: A system includes at least one hardware processor and a memory storing instructions that, when executed by the at least one hardware processor, cause the at least one hardware processor to perform operations including receiving consumption data associated with a user consuming content on one or more user computing devices, determining a preference associated with content consumption of the user based on the received consumption data, the preference including one or more of a delivery time, a computing device of the one or more user computing devices, and a venue, receiving a new content item, determining one or more of a target delivery time, a target computing device of the one or more user computing devices, and a target venue based on the determined preference, and transmitting the new content item to the target computing device for presentation to the user.

Abstract: A system includes at least one hardware processor and a memory storing instructions that, when executed by the at least one hardware processor, cause the at least one hardware processor to perform operations including receiving an initiation message associated with a collaboration event between a first user and a second user, the collaboration event is initiated by the first user, determining a target device from a pool of computing devices associated with the second user based on usage history of each computing device in the pool of computing devices, initiating a collaboration session with the second user via the target device, and presenting collaborative content to the second user via the target device during the collaboration session.

Abstract: A method for providing a computer-implemented medical diagnosis includes receiving an input from a user comprising at least one symptom of the user. The method also includes providing the at least one symptom as an input to a medical model, the medical model being retrieved from memory. The medical model includes a probabilistic graphical model comprising probability distributions and relationships between symptoms and diseases. The method also includes performing inference on the probabilistic graphical model to obtain a prediction of the probability that the user has that disease. The method also includes outputting an indication that the user has a disease from the Bayesian inference, wherein the inference is performed using a counterfactual measure.

Abstract: A computer-implemented method of generating a PGM with causal information, said graphical model containing the causal relationship between a first variable and a second variable, the method comprising: receiving data at a processor, said data showing a correlation between the first variable and a second variable; producing a third variable by reducing the dimensionality of the graphical representation of the two dimensional data defined by the first variable and the second variable, determining determine the causal relationship between the first and third variables and the second and third variable, the causal discovery algorithm being able to determine if the first variable causes the third variable, the third variable causes the first variable, the second variable causes the third variable and the third variable causes the second variable; and outputting a graphical model indicating the direction of edges in a graphical representation of said PGM.

Abstract: Molecular assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis of the measured expression levels to provide information concerning the likely prognosis for said patient, and likelihood that said patient will have a recurrence of prostate cancer, or to classify the tumor by likelihood of clinical outcome or TMPRSS2 fusion status, are provided herein.

Abstract: An apparatus and method to machine cavities in die blanks having little to no taper. The apparatus includes an electrode tool (200) including intersecting walls coated with electrically insulating coating (258), an erosion face (204) comprising a cross section of the walls exposed through the electrically insulating coating, and a channel formed by the walls to supply electrolyte to the erosion face, the channels defined by interior surfaces of the walls and having an opening formed by edges of the erosion face. The method includes pulsed electrochemical machining a work piece with the electrode tool.

Abstract: Various embodiments illustrated herein disclose a latching mechanism that enables engagement of modules on a mobile scanning device. The latching mechanism includes a release switch that translates between a first position and a second position. The release switch is coupled to a latch body that includes a first tongue section and a second tongue section. The first tongue section engages with the mobile scanning device, while the second tongue section engages with an attachment member. When the release switch is moved to a first position, the mobile scanning device is disengaged. When the release switch is moved to the second position, the attachment member is disengaged.

Abstract: One or more dielectric barriers, such as, but not limited to, aluminum oxide (Al2O3), is used to isolate and protect super conductive (SC) structures. The SC structures are formed from SC materials, such as, but not limited to, niobium, from other surrounding materials. Using the barriers significantly reduces and/or eliminates the degradation of the superconducting properties of the SC structures during subsequent fabrication steps that employ elevated temperatures. As a result, incorporation of the barriers relaxes the need to use lower temperature fabrication processes and opens up possibilities for use of different more desirable processes and/or materials during subsequent fabrication steps.

Abstract: Embodiments disclosed herein provide for systems and methods of real-time revenue and cost attribution associated with user acquisition on a website page. The system and methods provide for the presentation of real-time analytics at the individual page and user level and allows the backend system to make real-time decisions that can impact profitability per user.

Abstract: Embodiments disclosed herein provide for systems and methods of a real-time optimization of advertisement placements and advertisement types on a webpage. The system and methods provide for receiving signals on both the buy side (i.e., audience acquisition) and the sell side (i.e., the display of ads), and then transmitting the signals to the webpage to make decisions on what to show and what not to show. Further, machine learning may be utilized to understand exactly what the user is seeing and experiencing to make appropriate changes based on that specific user at that specific time.

Abstract: A virtual printing system includes a driver system, a network, a virtual print server, a database, and a search and report terminal to capture and store a print stream in PDF or PDF/A format. The driver system captures and converts metadata and print data from the client devices into a print stream. The virtual printer receives and prints the print stream as PDF or PDF/A files. The search and report terminal aids in searching within the PDF or PDF/A files.

Abstract: A data system includes an information bus, a volatile memory located on the information bus, and an MRAM located on the information bus. The data system includes threat detection circuitry. In response to a threat condition to the MRAM, data is transferred via the information bus from the MRAM to the volatile memory for storage during a threat to the MRAM as indicated by the threat condition. In some examples, the threat condition is characterized as a magnetic field exposure.

Abstract: A dynamic testing system for sealing devices includes a shaft that is reciprocated in a bore through a body. The shaft includes a first seal assembly and a second seal assembly disposed a distance apart on the shaft. When the shaft is inserted into the bore, the first seal assembly and the second seal assembly form a fluid-tight seal between the external surface of the shaft and the internal surface of the bore—this forms a fluid-tight cavity between the seal assemblies. Sealing devices in each of the first seal assembly and the second seal assembly experience chemical attack and mechanical wear. One or more axial force measurement sensors measure the force applied by a prime mover to reciprocate the shaft within the bore. Data acquisition circuitry collects the force information and generates a graphical output that plots friction force against reciprocating cycle count.