Abstract: Disclosed herein is a composition for ultrasensitive bioassay applications. The composition includes a plurality of dispersible, nanoparticles having a size less than 500 nm. The nanoparticles contain a metal catalyst or a metal catalyst precursor. The nanoparticles are conjugated to at least one biospecific binding reactant that is selectively reactive with a target analyte. The composition includes a dispersing medium. A method and a kit for conducting bioassays are described.

Abstract: Disclosed herein is a composition for ultrasensitive bioassay applications. The composition includes a plurality of dispersible, nanoparticles having a size less than 500 nm. The nanoparticles are contain a metal catalyst or a metal catalyst precursor. The nanoparticles are conjugated to at least one biospecific binding reactant that is selectively reactive with a target analyte. The composition includes a dispersing medium. A method and a kit for conducting bioassays is described.

Abstract: The invention relates to ultrasensitive bioanalytical assays based on the use of high-gain catalytic chemical amplification methods. The ultrasensitive bioanalytical assays of the invention utilize high gain catalytic chemical amplification methods to detect the presence and to quantify the concentrations of target analytes labeled with specific binding reagents or biomarkers comprising a catalyst or a catalyst precursor.

Abstract: The invention relates to ultrasensitive bioanalytical assays based on the use of high-gain catalytic chemical amplification methods. The ultrasensitive bioanalytical assays of the invention utilize high gain catalytic chemical amplification methods to detect the presence and to quantify the concentrations of target analytes labeled with specific binding reagents or biomarkers comprising a catalyst or a catalyst precursor.

Abstract: An element comprising a support on which is disposed an organic electroconductive polymeric layer containing a conductive polymer such that when a printing solution containing a conductivity enhancing agent contacts said electroconductive layer, the resistivity of the areas that are contacted with a printing solution decreases by at least a factor of 10. A method for producing an electrode pattern in the substrate is also disclosed.

Abstract: A method for producing an electrode pattern in a conductive polymeric layer comprising the steps of: (a) contacting a charge pattern with an electrographic developer composition comprising a carrier and marking particles having a polarity opposite that of said charge pattern thereby producing a developed image pattern, wherein said marking particles contain a conductivity modifier or a precursor thereof; (b) applying the developed image pattern to a conductive layer containing a conductive polymer on a substrate and (c) transferring said image pattern onto a said conductive layer. An element formed by the method is also disclosed.

Abstract: The present disclosure relates to aqueous dispersions of silver (carboxylate-azine toner) particles wherein the azine content of the particles is from about 0.01 to 10% by weight relative to silver carboxylate. The carboxylates are typically silver salts of long chain fatty acids and the azine toners are the compounds that function as development accelerators and toning agents such as phthalazine. These silver (carboxylate-azine) particles can be used to formulate imaging forming compositions that are useful in aqueous thermographic or photothermographic imaging elements.

Abstract: A method for producing an electrode pattern in a conductive polymer disposed on a substrate, the method comprising the steps of: applying a layer containing a conductive polymer on a substrate; and printing a pattern on said layer using a printing solution containing a conductivity enhancing agent such that the resistivity of the areas that are contacted with the printing solution decreases by at least a factor of 10. A formulation and a thin film element for performing the method are also disclosed.

Abstract: An element for making patterns on an electroconductive substrate, the element comprising a support, on which is disposed: a) a conductive layer containing an electrically conductive polymer, a polyanion and a conductivity enhancing agent; and b) a mixing layer containing a thermally mobile material; wherein, upon imagewise heating the mixing layer, the thermally mobile material mixes with the conductive layer, thereby causing the initial surface resistivity (SR) of the conductive layer to imagewise increase from an initial value SRi, which is lower than 105?/square, to SRi?, ? being at least 102.

Abstract: A method for producing an electrode pattern in a conductive polymer disposed on a substrate, the method comprising the steps of: applying a layer containing a conductive polymer on a substrate; and printing a pattern on said layer using a printing solution containing a conductivity enhancing agent such that the resistivity of the areas that are contacted with the printing solution decreases by at least a factor of 10. A formulation and a thin film element for performing the method are also disclosed.

Abstract: An element for making patterns on an electroconductive substrate, the element comprising a support, on which is disposed: a) a conductive layer containing an electrically conductive polymer, a polyanion and a conductivity enhancing agent; and b) a mixing layer containing a thermally mobile material; wherein, upon imagewise heating the mixing layer, the thermally mobile material mixes with the conductive layer, thereby causing the initial surface resistivity (SR) of the conductive layer to imagewise increase from an initial value SRi, which is lower than 105 ?/square, to SRi?, ? being at least 102.

Abstract: An element comprising a support on which is disposed an organic electroconductive polymeric layer containing a conductive polymer such that when a printing solution containing a conductivity enhancing agent contacts said electroconductive layer, the resistivity of the areas that are contacted with a printing solution decreases by at least a factor of 10. A method for producing an electrode pattern in the substrate is also disclosed.

Abstract: A method for producing an electrode pattern in a conductive polymeric layer comprising the steps of: (a) contacting a charge pattern with an electrographic developer composition comprising a carrier and marking particles having a polarity opposite that of said charge pattern thereby producing a developed image pattern, wherein said marking particles contain a conductivity modifier or a precursor thereof; (b) applying the developed image pattern to a conductive layer containing a conductive polymer on a substrate and (c) transferring said image pattern onto a said conductive layer. An element formed by the method is also disclosed.

Abstract: An imaging material comprising a support having disposed thereon: a) at least one image-formning layer, and b) at least one transparent electrically conductive antistatic layer that comprises electronically conductive polymer particles, a neutral-charge conductivity enhancer, and a polymeric binder comprising gelatin or gelatin derivatives.

Abstract: The present disclosure relates to aqueous dispersions of silver (carboxylate-azine toner) particles wherein the azine content of the particles is from about 0.01 to 10% by weight relative to silver carboxylate. The carboxylates are typically silver salts of long chain fatty acids and the azine toners are the compounds that function as development accelerators and toning agents such as phthalazine. These silver (carboxylate-azine) particles can be used to formulate imaging forming compositions that are useful in aqueous thermographic or photothermographic imaging elements.

Abstract: A thermally imageable element can be imaged using heat alone without the need for photosensitivity or post-imaging processing. The element contains image-forming chemistry that comprises i) image precursor chemistry and ii) a catalyst or a catalyst precursor that upon imagewise heating is capable of promoting thermally induced image formation with the image precursor chemistry. The image-forming chemistry i) and ii) components are in reactive association and uniformly dispersed or dissolved within a binder in one or more layers of the element. Thus, the element is capable of being thermally addressed to provide a visible image as a result of thermally induced catalytic transformation of the image-forming chemistry.

Abstract: A thermally imageable element can be imaged using heat alone without the need for photosensitivity or post-imaging processing. The element contains image-forming chemistry that comprises i) image precursor chemistry and ii) a catalyst or a catalyst precursor that upon imagewise heating is capable of promoting thermally induced image formation with the image precursor chemistry. The image-forming chemistry i) and ii) components are in reactive association and uniformly dispersed or dissolved within a binder in one or more layers of the element. Thus, the element is capable of being thermally addressed to provide a visible image as a result of thermally induced catalytic transformation of the image-forming chemistry.

Abstract: Photothermographic materials prepared using aqueous formulations include silver halides that are chemically sensitized using certain tellurium-containing compounds. Such tellurium-containing chemical sensitizing compounds are generally provided in aqueous solution or in an aqueous solid particulate dispersion and can be represented by the following Structure I, II, or III: Te(L)m(X1)n  (II) Pd(X2)2[Te(R′)2]2  (III) wherein X represents the same or different COR, CSR, CNRRa, CR, PRRa, or P(OR)2 groups, R and Ra are independently alkyl, alkenyl, or aryl groups, L is a ligand derived from a neutral Lewis base, X1 and X2 independently represent a halo, OCN, SCN, S2CNRRa, S2COR, S2CSR S2P(OR)2, S2PRRa, SeCN, TeCN, CN, SR, OR, alkyl, aryl, N3, or O2CR group, R′ is an alkyl or aryl group, p is 2 or 4, m is 0, 1, 2, or 4, and n is 2 or 4 provided that when m is 0 or 2, n is 2 or 4, and when m is 1 or 4, n is 2.

Abstract: Image-forming materials including photographic, thermographic, and thermally-developable imaging materials include one or more transparent electrically conductive, non-charging layers to provide antistatic control on one or both sides of subbed or unsubbed supports. The electrically conductive, non-charging layers comprise colloidal, electrically conductive polymer particles that can be dispersed in a film-forming binder in an amount to provide from about 10 to about 90 volume % of polymer particles. Particularly useful polymer particles include pyrrole-containing, thiophene-containing, and aniline-containing polymers. The particles generally exhibit a packed powder specific resistivity of 105 ohm-cm or less and generally have a mean diameter of 0.5 &mgr;m or less. The electrically conductive, non-charging layers generally exhibit a surface electrical resistivity of less than 1×1012 ohm per square.

Abstract: The present disclosure relates to aqueous dispersions of silver (carboxylate-azine toner) particles wherein the azine content of the particles is from about 0.01 to 10% by weight relative to silver carboxylate. The carboxylates are typically silver salts of long chain fatty acids and the azine toners are the compounds that function as development accelerators and toning agents such as phthalazine. These silver (carboxylate-azine) particles can be used to formulate imaging forming compositions that are useful in aqueous thermographic or photothermographic imaging elements.