Abstract: The present invention relates to methods, compositions, and kits for increasing the activation of effector T cells in a subject or inhibiting the activation of effector T cells in a subject by increasing or decreasing TNFR2 (CD 120b) signaling respectively. The present invention also relates to methods, compositions, and kits for treating diseases such as cancer, infections, and autoimmune diseases.

Abstract: The present invention relates to a method for treating and/or preventing a disease associated with glucose toxicity in a subject which may comprise administering to the subject a compound that reduces the level of Bim, PUMA and/or Bax activity in a cell of the subject. Furthermore, provided is a method for culturing cells susceptible to exposure to high concentrations of glucose, which may comprise delivering to the cells, or progenitor cells thereof, a compound that reduces the level of Bim, PUMA and/or Bax activity in the cells.

Abstract: A buying and selling process for selling and buying products and services allows buyers to post their desire-to-buy (DTB) to sellers. The sellers can respond to the DTBs by making desire-to-sell (DTS) Offers which match the DTB criteria that includes the specified product, price and DTB timing. Buyers either chose to accept or reject the offer. After a sufficient number of buyers have accepted the DTS Offer above the minimum volume of buyers for activation, the seller activates the purchase of the product or service. The buyers receive a right-to-buy (RTB) notice from the seller specifying the deal fulfillment process, including confirmation of the right-to-buy price (RTBP).

Abstract: The present invention relates to a method for treating and/or preventing a disease associated with glucose toxicity in a subject which may comprise administering to the subject a compound that reduces the level of Bim, PUMA and/or Bax activity in a cell of the subject. Furthermore, provided is a method for culturing cells susceptible to exposure to high concentrations of glucose, which may comprise delivering to the cells, or progenitor cells thereof, a compound that reduces the level of Bim, PUMA and/or Bax activity in the cells.

Abstract: An aircraft rear position light device (1) has a modular configuration. The device utilizes solid-state light sources. In an exemplary embodiment, the light sources are side-emitting light-emitting diodes (LEDs) (40), which are attached to a heat sink (30). A reflector (200) is positioned next to each of the LEDs. The device further includes an outer lens (10) with an integrated cut-off shield (110) and optical treatments (120). The configuration of LEDs and reflectors, in conjunction with the cut-off shield and optical treatments, allows the emitted light to satisfy predetermined minimum and maximum angular intensity requirements. An electronics module (50) is also attached to the heat sink to connect the LEDs to a power source in the aircraft. Electronic updates may be made by replacing the electronics module.

Abstract: An aircraft forward position lighting device (1) has a modular configuration, including a mounting module (20) containing solid-state light sources, e.g., light-emitting diodes (LEDs) (210, 230). The mounting module also includes reflectors 220. The pattern of light emanating from the light sources and reflectors satisfy Federal Aviation Regulations (FARs) regarding minimum light intensity. The device includes a cut-off shield module (10) configured to provide angular cut-offs to the pattern of light, so that the device satisfies FARs regarding overlap between position lights. The device may also include a base assembly module (30) that contains electronic circuitry connecting the light sources to a power source in the aircraft. Electronic updates may be performed by replacing the base assembly module.

Abstract: A method for reducing the radiation amplitude of material vibration modes (division vibrations) from a loudspeaker transducer diaphragm mechanically vibrated for the purpose of transforming an electrical signal into an acoustic signal. The diaphragm material may consist of formed paper or plastic sheet materials or molded paper pulp. The amplitude reduction of material vibration modes and pressure waves within the diaphragm material is accomplished by impressing small, shaped structures within the diaphragm material at critical locations determined by measurement with laser vibration analysis or position sensitive transient analysis of a loudspeaker transducer. The method is applied to the diaphragm material after it has been formed into the shape of a loudspeaker transducer diaphragm, either before or after the diaphragm has been assembled into a loudspeaker transducer.

Abstract: A decorative lamp display panel assembly for attachment to out door wall/post lanterns, or like structure, such assembly having a removable display panel having a decorative picture and/or indicia thereon. A top frame member is releasably secured to the top edge of the display panel and a bottom frame member is releasably secured to the bottom edge of the display panel. A support arm assembly is connected to the top frame member at a front end, and to a clamp member at the rear end. The clamp member has finger members that can be bent outwardly so that they can be attached to different diameter structure on an outdoor lantern. The support arm assembly can be extended and retracted, and it can be adjusted to different vertical angles to vary the height of the top frame member with respect to the clamp member.

Abstract: An aircraft rear position light device (1) has a modular configuration. The device utilizes solid-state light sources. In an exemplary embodiment, the light sources are side-emitting light-emitting diodes (LEDs) (40), which are attached to a heat sink (30). A reflector (200) is positioned next to each of the LEDs. The device further includes an outer lens (10) with an integrated cut-off shield (110) and optical treatments (120). The configuration of LEDs and reflectors, in conjunction with the cut-off shield and optical treatments, allows the emitted light to satisfy predetermined minimum and maximum angular intensity requirements. An electronics module (50) is also attached to the heat sink to connect the LEDs to a power source in the aircraft. Electronic updates may be made by replacing the electronics module.

Abstract: An aircraft forward position lighting device (1) has a modular configuration, including a mounting module (20) containing solid-state light sources, e.g., light-emitting diodes (LEDs) (210, 230). The mounting module also includes reflectors 220. The pattern of light emanating from the light sources and reflectors satisfy Federal Aviation Regulations (FARs) regarding minimum light intensity. The device includes a cut-off shield module (10) configured to provide angular cut-offs to the pattern of light, so that the device satisfies FARs regarding overlap between position lights. The device may also include a base assembly module (30) that contains electronic circuitry connecting the light sources to a power source in the aircraft. Electronic updates may be performed by replacing the base assembly module.