Abstract: The present disclosure provides a system and method for comprehensive data synchronization management between a sponsor-company's central electronic-laboratory-notebook system and either multiple contract-research-organizations or research sites. The system features a data loader server that can be deployed on-premise or in the cloud and allows scheduling of synchronization jobs of electronic-laboratory-notebook. The data loader software communicates to the contract research organization and the sponsor company's electronic laboratory notebook and executes scheduled or on-demand jobs. The data loader software may synchronized subsequent update of the data and may automatically delete the data from the contract research organization's site once a given transfer is complete. In some implementations, the method and system is configured for automation, scalability, and high-performance operations that focused on efficiency, security, configurability, and privacy/intellectual property protection.

Abstract: The present disclosure provides a system and method for comprehensive data synchronization management between a sponsor-company's central electronic-laboratory-notebook system and either multiple contract-research-organizations or research sites. The system features a data loader server that can be deployed on-premise or in the cloud and allows scheduling of synchronization jobs of electronic-laboratory-notebook. The data loader software communicates to the contract research organization and the sponsor company's electronic laboratory notebook and executes scheduled or on-demand jobs. The data loader software may synchronized subsequent update of the data and may automatically delete the data from the contract research organization's site once a given transfer is complete. In some implementations, the method and system is configured for automation, scalability, and high-performance operations that focused on efficiency, security, configurability, and privacy/intellectual property protection.

Abstract: The present application relates to amine salts of prostaglandin analogs and their uses for the preparation of substantially pure prostaglandin analogs. Specific embodiments relate to amine salts of tafluprost and their uses for the preparation of substantially pure tafluprost.