Abstract: Systems and methods for managing a power budget are provided. The method includes designating, by a power budget manager implemented on at least one processor, each of one or more applications with an individual quality of service (QoS) designation, the one or more applications executable by the at least one processor, assigning, by the power budget manager, a throttling priority to each of the one or more applications based on the individual QoS designations, determining, by the power budget manager, whether a platform mitigation threshold is exceeded, and responsive to determining that the platform mitigation threshold is exceeded, throttling, by the power budget manager, processing power allocated to at least one application of the one or more applications based on the throttling prioritization.

Abstract: Provided herein is a method of characterising a target polynucleotide as it moves with respect to a nanopore using a motor protein. Also provided are polynucleotide adapters and kits comprising such adapters. The methods, kits and adapters find use in characterising polynucleotides, for example in sequencing.

Abstract: The present invention relates to a heat exchanger unit (13) for exchanging heat between a first fluid and a second fluid. The unit (13) comprises a flow passage for the first fluid and a flow passage for the second fluid, the flow passages are connected to inlets (9) and outlets (10) of the heat exchanger unit (13) through which the first and the second fluid flow into and out of the heat exchanger unit (13).