Patents by Inventor Mark R. Etzel

Mark R. Etzel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220295809
    Abstract: The present invention concerns a method for concentrating dairy proteins. The method includes producing and using negatively-charged ultrafiltration membranes to achieve high hydraulic permeability with low sieving coefficients. The method thus yields good protein concentration at a fast rate.
    Type: Application
    Filed: June 6, 2022
    Publication date: September 22, 2022
    Inventors: Mark R. Etzel, Abhiram Arunkumar, Shantanu Agarwal
  • Publication number: 20200397020
    Abstract: The present invention concerns methods of isolating milk proteins. Methods of the invention include charged ultrafiltration processes that use variations in pH to further separate protein species.
    Type: Application
    Filed: August 31, 2020
    Publication date: December 24, 2020
    Inventors: Mark R. Etzel, Thatcher Root, Abhiram Arunkumar, Seyhun Gemili
  • Patent number: 10638775
    Abstract: The present invention concerns methods of isolating milk proteins. Methods of the invention include charged ultrafiltration processes that use variations in pH to further separate protein species.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: May 5, 2020
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Mark R. Etzel, Thatcher Root, Abhiram Arunkumar, Seyhun Gemili
  • Patent number: 10604742
    Abstract: A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: March 31, 2020
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventor: Mark R. Etzel
  • Publication number: 20190254301
    Abstract: The present invention concerns a method for concentrating dairy proteins. The method includes producting and using negatively-charged ultrafiltration membranes to achieve high hydraulic permeability with low sieving coefficients. The method thus yields good protein concentration at a fast rate.
    Type: Application
    Filed: April 30, 2019
    Publication date: August 22, 2019
    Inventors: Mark R. Etzel, Abhiram Arunkumar, Shantanu Agarwal
  • Publication number: 20190249150
    Abstract: A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.
    Type: Application
    Filed: April 24, 2019
    Publication date: August 15, 2019
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventor: Mark R. Etzel
  • Patent number: 10316296
    Abstract: A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: June 11, 2019
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventor: Mark R. Etzel
  • Patent number: 10258074
    Abstract: Medical foods containing glycomacroprotein and additional supplemented amounts of arginine, leucine, and optionally other amino acids, such as tyrosine, are disclosed. The medical foods can be used to provide the complete protein requirements for patients having metabolic disorders such as phenylketonuria.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: April 16, 2019
    Assignee: Wisonsin Alumni Research Foundation
    Inventors: Denise M. Ney, Mark R. Etzel
  • Publication number: 20180343890
    Abstract: The present invention concerns methods of isolating milk proteins. Methods of the invention include charged ultrafiltration processes that use variations in pH to further separate protein species.
    Type: Application
    Filed: August 3, 2018
    Publication date: December 6, 2018
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Mark R. ETZEL, Thatcher ROOT, Abhiram ARUNKUMAR, Seyhun GEMILI
  • Publication number: 20180094247
    Abstract: A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.
    Type: Application
    Filed: November 22, 2017
    Publication date: April 5, 2018
    Applicant: Wisconsin Alumni Research Foundation
    Inventor: Mark R. Etzel
  • Patent number: 9856459
    Abstract: A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.
    Type: Grant
    Filed: May 24, 2016
    Date of Patent: January 2, 2018
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventor: Mark R. Etzel
  • Patent number: 9492771
    Abstract: Polyethyleneimine and polyalkylene biguanide ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.
    Type: Grant
    Filed: September 18, 2009
    Date of Patent: November 15, 2016
    Assignee: 3M Innovative Properties Company
    Inventors: Mark R. Etzel, Kannan Seshadri, Jerald K. Rasmussen, Clinton P. Waller, Jr., Douglas E. Weiss, Yi He
  • Publication number: 20160264942
    Abstract: A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.
    Type: Application
    Filed: May 24, 2016
    Publication date: September 15, 2016
    Applicant: Wisconsin Alumni Research Foundation
    Inventor: Mark R. Etzel
  • Patent number: 9375499
    Abstract: A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.
    Type: Grant
    Filed: July 12, 2007
    Date of Patent: June 28, 2016
    Assignee: Wisconsin Alumni Research Foundation
    Inventor: Mark R. Etzel
  • Publication number: 20140248414
    Abstract: Medical foods containing glycomacroprotein and additional supplemented amounts of arginine, leucine, and optionally other amino acids, such as tyrosine, are disclosed. The medical foods can be used to provide the complete protein requirements for patients having metabolic disorders such as phenylketonuria.
    Type: Application
    Filed: May 9, 2014
    Publication date: September 4, 2014
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Denise M. Ney, Mark R. Etzel
  • Publication number: 20140234506
    Abstract: The present invention concerns concentrating dairy proteins. Methods of the invention include the production and use of negatively-charged ultrafiltration membranes to achieve high hydraulic permeability with low sieving coefficients.
    Type: Application
    Filed: February 18, 2014
    Publication date: August 21, 2014
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Mark R. ETZEL, Abhiram ARUNKUMAR, Shantanu AGARWAL
  • Patent number: 8604168
    Abstract: Medical foods containing glycomacroprotein and additional supplemented amounts of arginine, leucine, and optionally other amino acids, such as tyrosine, are disclosed. The medical foods can be used to provide the complete protein requirements for patients having metabolic disorders such as phenylketonuria.
    Type: Grant
    Filed: June 11, 2010
    Date of Patent: December 10, 2013
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Denise M. Ney, Mark R. Etzel
  • Patent number: 8586338
    Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: November 19, 2013
    Assignees: 3M Innovative Properties Company, Wisconsin Alumni Research Foundation
    Inventors: Mark R. Etzel, Yi He, Steven M. Heilmann, Jerald K. Rasmussen, Kannan Seshadri, Simon K. Shannon, Clinton P. Waller, Jr., Douglas E. Weiss
  • Publication number: 20120029165
    Abstract: The present invention concerns methods of isolating milk proteins. Methods of the invention include charged ultrafiltration processes that use variations in pH to further separate protein species.
    Type: Application
    Filed: July 12, 2011
    Publication date: February 2, 2012
    Inventors: Mark R. Etzel, Thatcher Root, Abhiram Arunkumar, Seyhun Gemili
  • Patent number: 8071152
    Abstract: The present invention concerns methods and compositions that involve whey protein isolates. Methods of the invention include purification processes for preparing whey proteins that are substantially nondenatured across a range of pH, including their isoelectric points. As such, they have low turbidity in solution across a wide range of pH values. Whey protein isolates can be integrated into compositions and solutions that have nutritional, pharmaceutical, and other applications.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: December 6, 2011
    Assignees: Wisconsin Alumni Research Foundation, Grande Cheese Company
    Inventors: Mark R. Etzel, Thomas R. Helm, Harit K. Vyas