Abstract: Method and system are provided for creating a self-sealing pressurized limb enclosure for the assessment of pressure effects on the limb. Embodiments can be self-sealing in that the seal is created by the positive pressure in the enclosure relative to the external environment and does not necessitate contact pressure at the seal location that exceeds the pressure in the enclosure. The seal accounts for anatomical size differences as well as deformations in the size and shape of the limb due to pressure. Furthermore, the seal maintains function in the presence of skin and tissue movement. In operation, the system can be used by an individual without external assistance.

Abstract: Technologies for measuring a hydration level of a user includes a hydration measurement device having an arm position sensor and one or more reflectance sensors. The hydration measurement device generates sensor data indicative of a position of a user's arm using the arm position sensor. The hydration measurement device performs reflectance measurements with the reflectance sensor(s) at a first position that is determined based on the sensor data and a second position that is raised relative to the first position that is also based on the sensor data. The hydration measurement device determines a hematocrit of the user's blood based on the reflectance measurements and determines a hydration level of the user based on the determined hematocrit. Other embodiments are described and claimed.

Abstract: The present invention provides methods and apparatuses to assess vascular stiffness of a subject, and to assess diabetes or hypertension from the assessment of vascular stiffness. Example embodiments comprise determining arrival at a peripheral site of a blood pressure wave as a function of time relative to the cardiac cycle of the subject at a plurality of measurement conditions, wherein at least two of the conditions are characterized by at least one of: (a) different central transmural pressure, (b) different peripheral transmural pressure; assessing vascular stiffness from the determinations at the plurality of measurement conditions.

Abstract: Method and systems provide for reliable, convenient, and cost-effective personalized assessment of hemodynamic status in the ambulatory heart failure patient. The method and apparatus use pulse contour analysis of data obtained through observation of the patient for determination of hemodynamic status, and for determination of day-to-day changes in hemodynamic status. Observational assessment of the patient includes monitoring during activities of daily living including sleeping, sitting and standing. These activities create changes in venous return that are used to evaluate cardiac function or changes in cardiac function. The method and system infer body position by using position and motion information obtained by the system. Changes in cardiac function over time or due to changes in body pose are evaluated for the assessment of hemodynamic status, with a focus on changes resulting from fluid overload.

Abstract: Method and system are provided for creating a self-sealing pressurized limb enclosure for the assessment of pressure effects on the limb. Embodiments can be self-sealing in that the seal is created by the positive pressure in the enclosure relative to the external environment and does not necessitate contact pressure at the seal location that exceeds the pressure in the enclosure. The seal accounts for anatomical size differences as well as deformations in the size and shape of the limb due to pressure. Furthermore, the seal maintains function in the presence of skin and tissue movement. In operation, the system can be used by an individual without external assistance.

Abstract: One or more processors may be configured to receive, via a radio from one or more sensors, one or more streams of sensor values indicating: (1) accelerations of a boxer's arm within a first range of acceleration, measured by a first acceleration sensor, (2) accelerations of a boxer's arm within a second range of acceleration, measured by a second acceleration sensor, and (3) rotation of the boxer's arm measured by a gyroscope sensor. The one or more processors may be configured to determine, based on the received sensor values from the first acceleration sensor, whether a punch landed but not to measure a force or velocity of the punch. The one or more processors may be configured to determine, based on the received sensor values from the second acceleration sensor, at least one of a force or a velocity of the punch but not to detect whether the punch landed.

Abstract: The systems and methods described herein provide hands free motor control mechanisms based on the natural and inherent movements associated with an activity of interest, and can be combined with gesture communication based upon defined movements by the participant.

Abstract: The present invention provides methods and apparatuses to assess vascular stiffness of a subject, and to assess diabetes or hypertension from the assessment of vascular stiffness. Example embodiments comprise determining arrival at a peripheral site of a blood pressure wave as a function of time relative to the cardiac cycle of the subject at a plurality of measurement conditions, wherein at least two of the conditions are characterized by at least one of: (a) different central transmural pressure, (b) different peripheral transmural pressure; assessing vascular stiffness from the determinations at the plurality of measurement conditions.

Abstract: Sensor systems and methods for quantitative assessment of sports performance are disclosed. In one embodiment, a boxing data server comprises a memory storing predetermined profiles of arm acceleration or rotation over time for one or more types of punches, a radio for communicating with one or more sensors on one or more boxers, and one or more processors. The one or more processors may be configured to receive, via the radio from the one or more sensors, one or more streams of sensor values indicating: (1) accelerations of a boxer's arm within a first range of acceleration, measured by a first acceleration sensor, (2) accelerations of a boxer's arm within a second range of acceleration, measured by a second acceleration sensor, and (3) rotation of the boxer's arm measured by a gyroscope sensor. The one or more processors may be configured to determine, based on the received sensor values from the first acceleration sensor, whether a punch landed but not to measure a force or velocity of the punch.

Abstract: The present invention provides a method for assessing diabetes in an individual by characterization of a pulse waveform indicative of the response of a portion of the cardiovascular system of the individual to pressure pulses produced during the cardiac cycle, where “assessing diabetes” comprises determining the presence or likelihood of diabetes; the degree of progression of diabetes; a change in the presence, likelihood, or progression of diabetes; a probability of having, not having, developing, or not developing diabetes; the presence, absence, progression, or likelihood of complications from diabetes; or a combination thereof. Embodiments of the present invention comprise determining a measure of arterial compliance of the individual from the pulse waveform; and assessing diabetes based on the measure of arterial compliance.

Abstract: The present invention provides a method for assessing diabetes in an individual by characterization of a pulse waveform indicative of the response of a portion of the cardiovascular system of the individual to pressure pulses produced during the cardiac cycle, where “assessing diabetes” comprises determining the presence or likelihood of diabetes; the degree of progression of diabetes; a change in the presence, likelihood, or progression of diabetes; a probability of having, not having, developing, or not developing diabetes; the presence, absence, progression, or likelihood of complications from diabetes; or a combination thereof. Embodiments of the present invention comprise determining a measure of arterial compliance of the individual from the pulse waveform; and assessing diabetes based on the measure of arterial compliance.

Abstract: The present invention provides methods and apparatuses that can provide three dimensional measurements of objects, without contact and with advantages not present in the art. Embodiments of the invention can be used to provide noncontact biometrics, in small footprints.

Abstract: Example embodiments of the present invention provide methods and apparatuses that enable the detection of bubbles so that hemodynamic performance can be assured following an automated blood analyte measurement. An example apparatus according to the present invention comprises a blood access system, adapted to remove blood from a body and infuse at least a portion of the blood back into the body. The infusion of at least a portion of the blood back in to the body can be done in a manner to assure that no bubbles of clinical significance are injected into the patient. Additionally an example embodiment can assess for the presence of bubbles in the fluid column that can affect hemodynamic monitoring performance. If a condition exists where hemodynamic monitoring performance cannot be assured, an example embodiment can provide appropriate warning or corrective actions.

Abstract: Embodiments of the present invention provide an apparatus with a flexible probe suitable for determining properties of in vivo tissue from spectral information collected from various tissue sites. An illumination system provides light at a plurality of broadband ranges, which are communicated to a flexible optical probe. Light homogenizers and mode scramblers can be employed to improve the performance in some embodiments. The optical probe in some embodiments physically contacts the tissue, and in some embodiments does not physically contact the tissue. The optical probe receives light from the illumination system and transmits it to tissue, and receives light diffusely reflected in response to the broadband light, emitted from the in vivo tissue by fluorescence thereof in response to the broadband light, or a combination thereof. The optical probe can communicate the light to a spectrograph which produces a signal representative of the spectral properties of the light.

Abstract: The present invention provides methods and apparatuses related to measurement of analytes, including measurements of analytes in samples withdrawn from a patient.

Abstract: Embodiments of the present invention provide an apparatus suitable for determining properties of in vivo tissue from spectral information collected from various tissue sites. An illumination system provides light at a plurality of broadband ranges, which are communicated to an optical probe. The optical probe can be a flexible probe in some embodiments, allowing ease of application. Light homogenizers and mode scramblers can be employed to improve the performance in some embodiments. The optical probe in some embodiments physically contacts the tissue, and in some embodiments does not physically contact the tissue. The optical probe receives light from the illumination system and transmits it to tissue, and receives light diffusely reflected in response to the broadband light, emitted from the in vivo tissue by fluorescence thereof in response to the broadband light, or a combination thereof.

Abstract: The use of an optical or other measurement in a blood access system enables the determination of a fluid sample appropriate for measurement on a real time basis. This information can be used to control the blood access system and related measurement processes. The determination can be based on, for example, at least one of: optical density, optical scatter, analyte level, temperature, the absolute level of any of the preceding, the stability of any of the preceding, the rate of change of any of the preceding, or the value of any of the preceding relative to another determination. The determination can be made using, for example, at least one of: electrochemical sensor, ion specific electrode, capacitance measurement, impedance measurement, inductance measurement, conductivity measurement, optical measurement, and ultrasound measurement.

Abstract: The present invention relates to a blood analyte measurement system for the procurement of blood samples for measurement of blood properties such as analyte concentration or analyte presence. A blood access system can be coupled with a measurement system such as an electrochemical sensor, and can also be used with other measurement modalities. Embodiments of the present invention can facilitate accurate measurement of blood glucose by the clinician in a sterile manner. Embodiments of the present invention can also enable the calibration of the sensor at one or more calibration points. One desired analyte of measurement is glucose for the effective implementation of glycemic control protocols. Embodiments of the present invention can also be used for the measurement of other analytes such as arterial blood gases, lactate, hemoglobin, potassium and urea.

Abstract: The present invention relates to measurements of material properties by determination of the response of a sample to incident radiation, and more specifically to the measurement of analytes such as glucose or alcohol in human tissue. The invention is particularly useful in connection with noncontact optical sampling of skin. Some example embodiments of the invention provide for selection of preferred sampling locations responsive to optically-determined characteristics of the tissue. Some example embodiments of the invention provide for precise and repeatable alignment of the tissue based on optically-determined characteristics of the tissue.

Abstract: This invention relates to measurements of material properties by determination of the response of a sample to incident radiation, and more specifically to the measurement of analytes such as glucose or alcohol in human tissue. Some example embodiments of the present invention provide an optical sampling apparatus including an optical subsystem, having a receiver for receiving light expressed from tissue; and an alignment subsystem, adapted to urge a portion of a hand placed in operative relationship with the alignment subsystem into a defined configuration relative to the receiver. In some such example embodiments, the alignment subsystem includes a substrate having a plurality of projections therefrom disposed in a pattern such that the projections urge a portion of a hand placed on the substrate to a defined configuration relative to the receiver.