Abstract: Described herein are flexible keratoprosthesis devices and uses thereof. The keratoprosthesis devices (100) can include an anchor body (110) and a plurality of flexible haptics (120), wherein the plurality of flexible haptics can be attached to and can be capable of extending radially from the anchor body. The flexible keratoprosthesis devices can be implanted into the eye via a minimally invasive technique.

Abstract: Disclosed are devices, systems, and methods for restoring vision to a subject. In one embodiment, the vision restoration device comprises a projector configured to project one or more digital images onto a central retina of the subject and one or more lenses coupled to the projector and configured to focus the one or more digital images. The vision restoration device can also comprise an extraocular component configured to be implanted within the subject and comprising one or more processors programmed to execute instructions stored in a memory to wirelessly receive the one or more digital images from an extracorporeal device. The intraocular projection component can be connected or coupled to the extraocular component by a trans-scleral communication wire configured to cross the sclera of the eye. The trans-scleral communication wire is configured to transmit digital data between the extraocular component and the intraocular projection component.

Abstract: Described herein are methods of enhancing wound healing using silk-derived proteins (SDP), including low molecular weight SDP fragments. Also described are compositions for the treatment of wounds, including corneal wounds, skin wounds, surgical incisions, burns, and skin ulcers, comprising SDP fragments, including low molecular weight SDP fragments.

Abstract: Systems and methods for managing transactions of physical objects are disclosed. The system is connectable to a first distributed ledger adapted to record object transactions associated with transactions of one or more physical objects between parties. The system includes a second distributed ledger adapted to record data indicative of object handling operations carried out with respect to the one or more physical objects; and an object handling management module adapted to authenticate handling operations carried out with respect to the one or more physical objects. The object handling management module is configured and operable for obtaining parameters of execution of the handling operations, authenticating the parameters of execution of the handling operations, and recording the authenticated handling operations in the second distributed ledger.

Abstract: Described herein are flexible keratoprosthesis devices and uses thereof. The keratoprosthesis devices (100) can include an anchor body (110) and a plurality of flexible haptics (120), wherein the plurality of flexible haptics can be attached to and can be capable of extending radially from the anchor body. The flexible keratoprosthesis devices can be implanted into the eye via a minimally invasive technique.

Abstract: Disclosed are devices, systems, and methods for restoring vision to a subject. In one embodiment, the vision restoration device comprises a projector configured to project one or more digital images onto a central retina of the subject and one or more lenses coupled to the projector and configured to focus the one or more digital images. The vision restoration device can also comprise an extraocular component configured to be implanted within the subject and comprising one or more processors programmed to execute instructions stored in a memory to wirelessly receive the one or more digital images from an extracorporeal device. The intraocular projection component can be connected or coupled to the extraocular component by a trans-scleral communication wire configured to cross the sclera of the eye. The trans-scleral communication wire is configured to transmit digital data between the extraocular component and the intraocular projection component.

Abstract: Described herein are methods of enhancing wound healing using silk-derived proteins (SDP), including low molecular weight SDP fragments. Also described are compositions for the treatment of wounds, including corneal wounds, skin wounds, surgical incisions, burns, and skin ulcers, comprising SDP fragments, including low molecular weight SDP fragments.

Abstract: The present invention relates to peptides for inhibiting angiogenesis. The present invention also relates to methods of inhibiting angiogenesis and methods of treating disorders associated with VEGF-induced vascular permeability using the peptides of the invention.

Abstract: VEGF-B, as well as a combination of VEGF-B and VEGF-A, mediates peripheral nerve repair. Methods to treat damage to the peripheral nervous system are described.

Abstract: The present invention relates to peptides for inhibiting angiogenesis. The present invention also relates to methods of inhibiting angiogenesis and methods of treating disorders associated with VEGF-induced vascular permeability using the peptides of the invention.

Abstract: The present invention relates to peptides for inhibiting angiogenesis. The present invention also relates to methods of inhibiting angiogenesis and methods of treating disorders associated with VEGF-induced vascular permeability using the peptides of the invention.

Abstract: VEGF-B, as well as a combination of VEGF-B and VEGF-A, mediates peripheral nerve repair. Methods to treat damage to the peripheral nervous system are described.

Abstract: The present invention relates to peptides for inhibiting angiogenesis. The present invention also relates to methods of inhibiting angiogenesis and methods of treating disorders associated with VEGF-induced vascular permeability using the peptides of the invention.

Abstract: Methods, devices, and kits comprising a magnetic system for automation of blinking, or to provide temporary or permanent assistance with opening or closure of the eyelids to treat disorders of the eyelids, including lagophthalmos and ptosis.

Abstract: Methods, devices, and kits comprising a magnetic system for automation of blinking, or to provide temporary or permanent assistance with opening or closure of the eyelids to treat disorders of the eyelids, including lagophthalmos and ptosis.