Abstract: The present invention relates to a modular storage system for barrels. The modular storage system includes a base rick module, an aisle rick module, and an end rick module, whereby a plurality of each module type may be assembled to construct a rickhouse.

Abstract: The present invention relates to RNAi agents, e.g., double stranded RNA (dsRNA) agents, targeting the Factor XII (F12) gene. The invention also relates to methods of using such RNAi agents to inhibit expression of an F12 gene and to methods of preventing and treating an F12-associated disorder, e.g., heredity angioedema (HAE), prekallikrein deficiency, malignant essential hypertension, hypertension, end stage renal disease, Fletcher Factor Deficiency, thromboembolic disease, inflammatory disease, or Alzheimer's Disease.

Abstract: An apparatus includes a food product, at least one ingestible device associated with the food product to communicate information and at least one coating material surrounding the at least one ingestible device is disclosed. The ingestible device is associated with an ingestible medication to be ingested in conjunction with the food product. The coating is configured to release the at least one ingestible device upon the occurrence of an event.

Abstract: The present disclosure provides host cells, e.g., bacterial cells, that comprise a methionine decarboxylase enzyme for the treatment of diseases and disorders associated with methionine metabolism in a subject. The disclosure further provides pharmaceutical compositions and methods of treating disorders associated with methionine metabolism, such as homocystinuria.

Abstract: An ear level part for a hearing device may include a body containing at least two microphones acoustically connected to at least two microphone openings, the at least two microphone openings arranged in a microphone line, the body further comprising a flange, wherein a receiver is arranged within the body, wherein the flange has a sound exit for the receiver; and an upper tab generally protruding in a lateral direction from the body and configured to be positioned above the tragus of a user's ear and a lower tab generally protruding in a lateral direction from the body and configured to be positioned beneath the tragus of the user's ear thereby aligning the ear level part.

Abstract: A database system is operable to communicate first system metadata to a plurality of nodes in a first temporal period, where each node of the plurality of nodes updates corresponding system configuration data as the first system metadata. At least one database function is performed in the first temporal period via the plurality of nodes operating in conjunction with the first system metadata. Updated system metadata is determined based on a first metadata change applied the first system metadata. The first metadata change is communicated to the plurality of nodes in a second temporal period, where each node further updates the corresponding system configuration data as the updated system metadata based on applying the first metadata change to the first system metadata. The at least one database function is performed in the second temporal period via the plurality of nodes operating in conjunction with the updated system metadata.

Abstract: The disclosure provides compositions containing pure aticaprant, solvates of aticaprant, and methods of treating major depressive disorder using aticaprant.

Abstract: A method, system, and computer program product for trick play using partial video file chunks includes a processor to retrieve the selected video file from an HLS server, the video file having a plurality of video chunks, and each one of the video chunks beginning with an I-frame. The processor may determine an average size of the plurality of I-frames. The average I-frame size may be based on a bitrate speed of the video file. The processor may retrieve a portion equal to the average I-frame size of from the beginning of each one of the plurality of chunks of the video. The processor may receive a begin trick play request of the selected video and initiate trick play of the selected video. The trick play of the video includes displaying each portion of each one of the plurality of chunks of the video.

Abstract: The disclosure provides crystalline and amorphous forms of aticaprant. Also provided by the disclosure are pharmaceutical compositions comprising the amorphous or crystalline forms, methods of treating major depressive disorder using the amorphous or crystalline forms of aticaprant, amorphous or crystalline forms of aticaprant for use in the treatment of major depressive disorder in a human patient having anhedonia, uses of the amorphous or crystalline forms of aticaprant in the manufacture of a medicament for the treatment of major depressive disorder, and packages or pharmaceutical products comprising (i) amorphous or crystalline forms of aticaprant and (ii) instructions for treating major depressive disorder. In some aspects, the human patient treated as described herein has anhedonia.

Abstract: The present disclosure relates to compositions, including oral compositions in the form of tablets, comprising aticaprant and methods of using the same.

Abstract: An actuator arrangement for operating a clutch and a parking lock in a driveline of a motor vehicle comprises: a clutch having a clutch actuating member configured to drivingly connect or disconnect a clutch input part and a clutch output part; a parking lock having a locking element movable to a locking position to lock a ratchet wheel, and to a release position to release the ratchet wheel; and a parking lock actuating member for actuating the locking element; a controllable actuator with a movable actuator setting member which is movable into at least three setting positions and is operatively connected to the clutch actuating member and to the parking lock actuating member such that in a first setting position the parking lock is closed, in a second setting position the clutch is closed, and in a third setting position the clutch and the parking lock are opened.

Abstract: The disclosure provides methods for treating major depressive disorder in a human patient having moderate or severe anhedonia. The methods comprise administering to the patient in need thereof an effective amount of aticaprant, or a pharmaceutically acceptable salt thereof. In some embodiments, the patient had an inadequate response to other antidepressant therapy prior to treatment with aticaprant. In other embodiments, the other antidepressant therapy comprised a selective serotonin reuptake inhibitor (SSRI), serotonin-norepinephrine reuptake inhibitor (SNRI), or a combination thereof.

Abstract: A method, system, and computer program product for trick play using partial video file chunks includes a processor to retrieve the selected video file from an HLS server, the video file having a plurality of video chunks, and each one of the video chunks beginning with an I-frame. The processor may determine an average size of the plurality of I-frames. The average I-frame size may be based on a bitrate speed of the video file. The processor may retrieve a portion equal to the average I-frame size of from the beginning of each one of the plurality of chunks of the video. The processor may receive a begin trick play request of the selected video and initiate trick play of the selected video. The trick play of the video includes displaying each portion of each one of the plurality of chunks of the video.

Abstract: Technologies are disclosed for providing stream media content and/or metadata indicating stream media content. A media control device may receive a Digital Living Network Alliance (DLNA) hypertext transport protocol (HTTP) request from a media content device. The DLNA HTTP request may have a header created by the media content device. The media control device may interpret the DLNA HTTP request header. A first metadata may be identified in the DLNA HTTP request header that may indicate a request for stream media content information. The media control device may send a DLNA HTTP response to the media content device. The DLNA HTTP response may have a header that may include a second metadata indicating the stream media content information. The second metadata may include information enabling construction of a HTTP Live Streaming (HLS) master playlist, a program map table, and/or a program association table associated with the stream media content.

Abstract: The invention relates to a method for selectively configuring a container that contains an application, wherein user-authentication data are received by a container management component and forwarded via a container applicant to an authorisation server. This server transmits an authorisation response, on the basis of which a decision is made as to whether the application is allowed to be run in the container.

Abstract: The disclosure provides methods for treating major depressive disorder in a human patient having moderate or severe anhedonia. The methods comprise administering to the patient in need thereof an effective amount of aticaprant, or a pharmaceutically acceptable salt thereof. In some embodiments, the patient had an inadequate response to other antidepressant therapy prior to treatment with aticaprant. In other embodiments, the other antidepressant therapy comprised a selective serotonin reuptake inhibitor (SSRI), serotonin-norepinephrine reuptake inhibitor (SNRI), or a combination thereof.

Abstract: A hearing device including a shell to be worn at least in part in the ear canal and having an outer opening; a faceplate covering the outer opening of the shell and facing outwardly of the ear canal when the hearing device is worn in the ear canal; a transceiver configured to operate in an operating frequency range which is located within 2.4 GHz to 2.5 GHz; and a dipole antenna. The dipole antenna is integrated within the faceplate or at an outer surface of the faceplate in a manner so as to follow the contour of the outer surface of the faceplate to maximize radiation gain of the dipole antenna.

Abstract: An ear level part for a hearing device may include a body containing at least two microphones acoustically connected to at least two microphone openings, the at least two microphone openings arranged in a microphone line, the body further comprising a flange, wherein a receiver is arranged within the body, wherein the flange has a sound exit for the receiver; and an upper tab generally protruding in a lateral direction from the body and configured to be positioned above the tragus of a user's ear and a lower tab generally protruding in a lateral direction from the body and configured to be positioned beneath the tragus of the user's ear thereby aligning the ear level part.

Abstract: A device includes a housing, a tamper switch supported at the housing, and a tamper actuator receivable at the housing. The tamper actuator is movable between a tamper disabled position and a tamper enabled position. In the tamper disabled position, the tamper actuator is fixed in place at the housing. In the tamper enabled position, the tamper actuator is configured to move relative to the housing between a tamper switch engaged position and a tamper switch released position.