Abstract: A connection mechanism including a plurality of microstructure features. The connection mechanism includes a first strip, with a plurality of protrusions extending from the first strip, and a second strip, with a plurality of protrusions extending from the second strip. The protrusions define grooves between adjacent protrusions. A pressure sensitive adhesive is provided in at least some of the grooves. When the first and second strips are brought together, the protrusions from one strip are received in the grooves of the other, and some of the protrusions contact the pressure sensitive adhesive, thereby connecting the first and second strips. The connection mechanism can be used as a closure mechanism for a plastic storage bag.

Abstract: Phenotypic antimicrobial susceptibility testing (AST), the gold-standard diagnostic that indicates whether an antimicrobial will be clinically effective, often suffer the slowest times-to-result for the most resistant pathogens. Here we introduce novel assays to be performed in parallel with standard AST assays that enable rapid, same-shift reporting of AST results for a plurality of pathogens. The assays developed here are further capable of detecting resistance to carbapenems, the most powerful class of beta-lactams commonly used as “last-resort” antimicrobials.

Abstract: Disclosed embodiments relate to a footwear system. The footwear system includes a shoe, a first insole, and a second insole. The first insole is a fitting insole having a first volume. It is positioned within the shoe during a fitting of a potential wearer of the shoe. The fitting insole is removed after the fitting is completed. The second insole has a volume substantially similar to the first volume. The second insole adapted for positioning within the shoe if the first insole demonstrates an appropriate fit. The second insole is self-customizable and further adapted to conform to the imprint of the sole of the potential wearer.

Abstract: The invention relates to a polymeric treatment for a textile component. An exemplary method of treating a textile element for incorporation into at least a portion of an upper of an article of footwear includes applying a thermoplastic polymer to a textile element having at least one first region and at least one second region, selectively activating the thermoplastic polymer in the at least one first region to modify at least one structural property of the at least one first region, and leaving the thermoplastic polymer in the at least one second region of the textile element unactivated, wherein the at least one modified structural property of the at least one first region differs from at least one structural property of the at least one second region.

Abstract: A customizeable footbed, a self-customizing footwear having a customizable footbed, and a method for customizing a footbed to conform to contours of a foot is provided. The customizable footbed may include a plurality of packets, each packet comprising an exterior membrane defining a chamber therein, and an interior filling within the chamber. The interior filling may be selected from a group consisting of two or more components of a curable material that chemically react upon mixing of the components to irreversibly form a solid or semi-solid resin or a gel. The plurality of packets may be configured to burst upon application of a pressure such that the interior fillings of the packets flow into and mix within the intermediate space.

Abstract: A connection mechanism including a plurality of microstructure features. The connection mechanism includes a first strip, with a plurality of protrusions extending from the first strip, and a second strip, with a plurality of protrusions extending from the second strip. The protrusions define grooves between adjacent protrusions. A pressure sensitive adhesive is provided in at least some of the grooves. When the first and second strips are brought together, the protrusions from one strip are received in the grooves of the other, and some of the protrusions contact the pressure sensitive adhesive, thereby connecting the first and second strips. The connection mechanism can be used as a closure mechanism for a plastic storage bag.

Abstract: Conventional dispensers for a cosmetic fluid, such as a liquid, comprises a bottle having a housing for a low regulator, such as a roller or preferably a ball and a cap which is securable to the bottle by a single set of co-operating screw threads. An improved dispenser secures the cap to the bottle, and especially to the housing, by a plurality of sets of mounting elements, one of which comprises a cam providing axial movement of the cap when it is rotated around the bottle and the other a follower, such a lug and bayonet. One element is mounted on the interior of the cap and the other on the exterior of the bottle/housing. The mounting elements on the bottle/housing advantageously are separated both laterally around the periphery and axially so as to permit the mounting elements on the cap to pass axially between adjacent bottle elements and the cap to be rotated until matched sets of elements are brought into contact.

Abstract: In cosmetic dispensers for fluids, such as for example deodorants or antiperspirants comprising a bottle, a flow regulator in a housing mounted on the bottle and a cap rotatably mounted on the bottle or particularly onto the flow regulator housing, there is a risk that the housing can part from the bottle or be moved out of alignment by fitting or removal of the cap. This problem can be ameliorated or eliminated by employing a plurality of sets of anti-rotation elements at or adjacent to the mouth of the bottle around its periphery, each set comprising a peg and a socket. Preferably, the housing is bifurcated inward of the flow regulator, one wall extending within the bottle and the other wall extending out side the wall, and desirably the bottle wall is of reduced wall thickness in the overlap so that the exterior of the bottle surface and housing surface can be flush at their line of contact.