Patents by Inventor Mark Stanley Cushman

Mark Stanley Cushman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Janus kinase inhibitors and uses thereof
    Patent number: 10399979
    Abstract: The invention described herein pertains to selective Janus kinase (JAK) inhibitors and methods of use thereof. Also described are methods for treating diseases involved abnormal JAK/STAT signaling pathway in mammals using the described selective JAK inhibitors or a pharmaceutical formulation thereof.
    Type: Grant
    Filed: October 31, 2018
    Date of Patent: September 3, 2019
    Assignee: Purdue Research Foundation
    Inventors: Mark Stanley Cushman, Mohamed S. A. Elsayed
  • JANUS KINASE INHIBITORS AND USES THEREOF
    Publication number: 20190127377
    Abstract: The invention described herein pertains to selective Janus kinase (JAK) inhibitors and methods of use thereof. Also described are methods for treating diseases involved abnormal JAK/STAT signaling pathway in mammals using the described selective JAK inhibitors or a pharmaceutical formulation thereof.
    Type: Application
    Filed: October 31, 2018
    Publication date: May 2, 2019
    Applicant: Purdue Research Foundation
    Inventors: Mark Stanley Cushman, Mohamed S. A. Elsayed
  • Antimicrobial substituted thiazoles and methods of use
    Patent number: 9801861
    Abstract: Disclosed are compositions having activity against MRSA and/or VRSA, and methods of using the compositions to treat microbial infections.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: October 31, 2017
    Assignee: Purdue Research Foundation
    Inventors: Mark Stanley Cushman, Mohamed Seleem, Abdelrahman S Mayhoub
  • N-substituted indenoisoquinolines and syntheses thereof
    Patent number: 9796753
    Abstract: N-Substituted indenoisoquinoline compounds, and pharmaceutical formulations of N-substituted indenoisoquinoline compounds are described. Also described are processes for preparing N-substituted indenoisoquinoline compounds. Also described are methods for treating cancer in mammals using the described N-substituted indenoisoquinoline compounds or pharmaceutical formulations thereof.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: October 24, 2017
    Assignee: Purdue Research Foundation
    Inventors: Mark Stanley Cushman, Daniel Edward Beck
  • Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase I inhibitors
    Patent number: 9682990
    Abstract: The invention described herein pertains to substituted indenoisoquinoline compounds as described herein, wherein RA, RD, W, X and Y are defined herein, pharmaceutical compositions and formulations comprising the indenoisoquinoline compounds, their synthesis, and methods for their use in the treatment and/or prevention of cancer.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: June 20, 2017
    Assignee: Purdue Research Foundation
    Inventors: Mark Stanley Cushman, Daniel Edward Beck
  • ANTIMICROBIAL SUBSTITUTED THIAZOLES AND METHODS OF USE
    Publication number: 20160243088
    Abstract: Disclosed are compositions having activity against MRSA and/or VRSA, and methods of using the compositions to treat microbial infections.
    Type: Application
    Filed: April 29, 2016
    Publication date: August 25, 2016
    Inventors: Mark Stanley Cushman, Mohamed Seleem, Abdelrahman S. Mayhoub
  • N-SUBSTITUTED INDENOISOQUINOLINES AND SYNTHESES THEREOF
    Publication number: 20160229888
    Abstract: N-Substituted indenoisoquinoline compounds, and pharmaceutical formulations of N-substituted indenoisoquinoline compounds are described. Also described are processes for preparing N-substituted indenoisoquinoline compounds. Also described are methods for treating cancer in mammals using the described N-substituted indenoisoquinoline compounds or pharmaceutical formulations thereof.
    Type: Application
    Filed: April 27, 2016
    Publication date: August 11, 2016
    Inventors: Mark Stanley Cushman, Daniel Edward Beck
  • Antimicrobial substituted thiazoles and methods of use
    Patent number: 9353072
    Abstract: Disclosed are compositions having activity against MRSA and/or VRSA, and methods of using the compositions to treat microbial infections.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: May 31, 2016
    Assignee: Purdue Research Foundation
    Inventors: Mark Stanley Cushman, Mohamed Seleem, Abdelrahman S Mayhoub
  • ANTIMICROBIAL SUBSTITUTED THIAZOLES AND METHODS OF USE
    Publication number: 20140121249
    Abstract: Disclosed are compositions having activity against MRSA and/or VRSA, and methods of using the compositions to treat microbial infections.
    Type: Application
    Filed: October 31, 2013
    Publication date: May 1, 2014
    Inventors: Mark Stanley Cushman, Mohamed Seleem, Abdelrahman S. Mayhoub