Patents by Inventor Mark Thomas Holtzapple
Mark Thomas Holtzapple has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190301808Abstract: A heat exchanger includes a shell, and a tube assembly disposed in the shell, the tube assembly including at least one tube, wherein the tube has a pair of end sections having a first diameter and a central section extending between the end sections having a second diameter that is greater than the first diameter.Type: ApplicationFiled: December 13, 2017Publication date: October 3, 2019Applicant: The Texas A&M University SystemInventor: Mark Thomas Holtzapple
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Publication number: 20140242253Abstract: Herein disclosed is a process for solubilizing protein from a biological source selected from the group consisting of animal tissue and keratinous material and combinations thereof, the process comprising: forming an alkaline slurry comprising the biological source and a first alkali comprising hydrated lime or quicklime; heating the alkaline slurry to a first temperature of at least 50° C. for a first treatment time to solubilize protein while minimizing degradation of amino acids and obtain a first treated slurry; separating from the first treated slurry a first liquid product and a solid product, wherein the first liquid product comprises the solubilized protein and calcium; and removing at least a portion of the calcium from the liquid product by adjusting pH to higher than 8 to precipitate calcium and produce a low-calcium liquid product.Type: ApplicationFiled: March 19, 2014Publication date: August 28, 2014Applicant: THE TEXAS A&M UNIVERSITY SYSTEMInventors: Mark Thomas Holtzapple, Richard Read Davison, Guillermo Coward Kelly
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Publication number: 20130231467Abstract: A method of solubilizing protein that includes applying an alkali to a protein source to form a slurry; heating the slurry to a temperature sufficient to allow hydrolysis of protein in the protein source to obtain a reaction liquid comprising solubilized proteins, prions, and reactive solids; separating reactive solids from the reaction liquid to produce a separated reaction liquid, wherein the reactive solids comprise unsolubilized proteins; further heating the separated reaction liquid to an elevated temperature and holding for a time period sufficient to destroy prions in the separated reaction liquid, wherein the elevated temperature is between 75° C. and 250° C. and the time period is between 1 second and 5 hours; and neutralizing the reaction liquid with acid or an acid source to produce a neutralized liquid.Type: ApplicationFiled: February 20, 2013Publication date: September 5, 2013Applicant: EE-TERRABON, LLCInventors: Mark Thomas Holtzapple, Gary P. Noyes, Richard Davison, Cesar B. Granda
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Publication number: 20120258509Abstract: A method of biomass pretreatment that includes forming a mixture comprising alkali and lignocellulosic biomass; controlling at least one physical property of the mixture selected from the group of pressure, temperature, and a combination thereof; contacting the mixture with a fluid; fermenting at least a portion of the mixture; and collecting carboxylate salts formed from fermenting.Type: ApplicationFiled: June 20, 2012Publication date: October 11, 2012Applicant: The Texas A&M University SystemInventors: Mark Thomas Holtzapple, Richard Read Davison, Lee Leon Lowery, JR., Cesar Benigno Granda
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Patent number: 8283141Abstract: The disclosure includes a method, process and apparatus for the conversion of biomass to carboxylic acids and/or primary alcohols. The system may include a pretreatment/fermentation subsystem operable to produce a fermentation broth containing carboxylic acid salts from biomass, such as lignocellulosic biomass. The system may also include a dewatering subsystem operable to remove excess water from the fermentation broth to produce a concentrated product. The system may also includes an acid springing subsystem operable to produce a mixed carboxylic acid product. The system may also include a hydrogenation subsystem operable to produce an alcohol mixture, such as a mixture containing primary alcohols. Methods of operating this system or other systems to obtain a carboxylic acid or alcohol mixture are also provided.Type: GrantFiled: October 11, 2011Date of Patent: October 9, 2012Assignee: The Texas A&M University SystemInventors: Mark Thomas Holtzapple, Richard Davison
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Patent number: 8262853Abstract: According to one embodiment of the invention, a system for processing biomass includes a water-impermeable bottom liner, a gravel layer supported by the bottom liner, a drain pipe disposed within the gravel layer, a biomass input device operable to deliver biomass over the gravel layer to form a biomass pile, a lime input device operable to deliver lime to the biomass for pretreating the biomass, a distribution pipe elevated above the gravel layer, and a pump operable to circulate water through the biomass pile by delivering water to the distribution pipe and receiving water from the drain pipe after it has traveled through the biomass pile. According to another embodiment, a method for biomass pretreatment with alkali, conducted at ambient pressure for approximately 4-16 weeks at temperatures ranging from approximately 25° C. to 95° C. Biomass may be lignocellulosic biomass and may be rendered suitable for enzymatic digestion or pulp production.Type: GrantFiled: September 5, 2007Date of Patent: September 11, 2012Assignee: The Texas A&M University SystemInventors: Mark Thomas Holtzapple, Richard Read Davison, Lee Leon Lowery, Jr., Cesar Benigno Granda
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Patent number: 8124386Abstract: The disclosure includes a method, process and apparatus for the conversion of biomass to carboxylic acids and/or primary alcohols. The system may include a pretreatment/fermentation subsystem operable to produce a fermentation broth containing carboxylic acid salts from biomass, such as lignocellulosic biomass. The system may also include a dewatering subsystem operable to remove excess water from the fermentation broth to produce a concentrated product. The system may also includes an acid springing subsystem operable to produce a mixed carboxylic acid product. The system may also include a hydrogenation subsystem operable to produce an alcohol mixture, such as a mixture containing primary alcohols. Methods of operating this system or other systems to obtain a carboxylic acid or alcohol mixture are also provided.Type: GrantFiled: October 7, 2010Date of Patent: February 28, 2012Assignee: The Texas A&M University SystemInventors: Mark Thomas Holtzapple, Richard Davison
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Publication number: 20120034663Abstract: The disclosure includes a method, process and apparatus for the conversion of biomass to carboxylic acids and/or primary alcohols. The system may include a pretreatment/fermentation subsystem operable to produce a fermentation broth containing carboxylic acid salts from biomass, such as lignocellulosic biomass. The system may also include a dewatering subsystem operable to remove excess water from the fermentation broth to produce a concentrated product. The system may also includes an acid springing subsystem operable to produce a mixed carboxylic acid product. The system may also include a hydrogenation subsystem operable to produce an alcohol mixture, such as a mixture containing primary alcohols. Methods of operating this system or other systems to obtain a carboxylic acid or alcohol mixture are also provided.Type: ApplicationFiled: October 11, 2011Publication date: February 9, 2012Applicant: The Texas A&M University SystemInventors: Mark Thomas HOLTZAPPLE, Richard Davison
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Publication number: 20110039315Abstract: The disclosure includes a method, process and apparatus for the conversion of biomass to carboxylic acids and/or primary alcohols. The system may include a pretreatment/fermentation subsystem operable to produce a fermentation broth containing carboxylic acid salts from biomass, such as lignocellulosic biomass. The system may also include a dewatering subsystem operable to remove excess water from the fermentation broth to produce a concentrated product. The system may also includes an acid springing subsystem operable to produce a mixed carboxylic acid product. The system may also include a hydrogenation subsystem operable to produce an alcohol mixture, such as a mixture containing primary alcohols. Methods of operating this system or other systems to obtain a carboxylic acid or alcohol mixture are also provided.Type: ApplicationFiled: October 7, 2010Publication date: February 17, 2011Applicant: THE TEXAS A&M UNIVERSITY SYSTEMInventors: Mark Thomas HOLTZAPPLE, Richard DAVISON
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Patent number: 7820417Abstract: The disclosure includes a method, process and apparatus for the conversion of biomass to carboxylic acids and/or primary alcohols. The system may include a pretreatment/fermentation subsystem operable to produce a fermentation broth containing carboxylic acid salts from biomass, such as lignocellulosic biomass. The system may also include a dewatering subsystem operable to remove excess water from the fermentation broth to produce a concentrated product. The system may also includes an acid springing subsystem operable to produce a mixed carboxylic acid product. The system may also include a hydrogenation subsystem operable to produce an alcohol mixture, such as a mixture containing primary alcohols. Methods of operating this system or other systems to obtain a carboxylic acid or alcohol mixture are also provided.Type: GrantFiled: June 16, 2005Date of Patent: October 26, 2010Assignee: The Texas A&M University SystemInventors: Mark Thomas Holtzapple, Richard Davison
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Publication number: 20100202936Abstract: A process for solubilization of protein including application of an alkali, such as lime, and heating. The process may also involve lime recovery and may be accomplished in a single stage or two stages to separate protein solubilized from labile and recalcitrant sources. Systems and devices for use in such process, including a continuous stirred tank reactor and a plug flow reactor are also involved.Type: ApplicationFiled: March 5, 2010Publication date: August 12, 2010Applicants: TEXAS A&M UNIVERSITY SYSTEM, TERRABON TECHNOLOGY CORP.Inventors: Mark Thomas Holtzapple, Gary P. Noyes, Richard Davison, Cesar B. Granda
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Patent number: 7705116Abstract: A process for solubilization of protein including application of an alkali, such as lime, and heating. The process may also involve lime recovery and may be accomplished in a single stage or two stages to separate protein solubilized from labile and recalcitrant sources. Systems and devices for use in such process, including a continuous stirred tank reactor and a plug flow reactor are also involved.Type: GrantFiled: June 1, 2005Date of Patent: April 27, 2010Assignees: Texas A&M University System, Terrabon Technology Corp.Inventors: Mark Thomas Holtzapple, Gary P. Noyes, Richard Davison, Cesar B. Granda
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Publication number: 20090325251Abstract: The disclosure includes a method, process and apparatus for the conversion of biomass to carboxylic acids and/or primary alcohols. The system may include a pretreatment/fermentation subsystem operable to produce a fermentation broth containing carboxylic acid salts from biomass, such as lignocellulosic biomass. The system may also include a dewatering subsystem operable to remove excess water from the fermentation broth to produce a concentrated product. The system may also includes an acid springing subsystem operable to produce a mixed carboxylic acid product. The system may also include a hydrogenation subsystem operable to produce an alcohol mixture, such as a mixture containing primary alcohols. Methods of operating this system or other systems to obtain a carboxylic acid or alcohol mixture are also provided.Type: ApplicationFiled: September 8, 2009Publication date: December 31, 2009Applicant: The Texas A&M university SystemInventors: Mark Thomas Holtzapple, Richard Davison
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Publication number: 20080121359Abstract: According to one embodiment of the invention, a system for processing biomass includes a water-impermeable bottom liner, a gravel layer supported by the bottom liner, a drain pipe disposed within the gravel layer, a biomass input device operable to deliver biomass over the gravel layer to form a biomass pile, a lime input device operable to deliver lime to the biomass for pretreating the biomass, a distribution pipe elevated above the gravel layer, and a pump operable to circulate water through the biomass pile by delivering water to the distribution pipe and receiving water from the drain pipe after it has traveled through the biomass pile. According to another embodiment, a method for biomass pretreatment with alkali, conducted at ambient pressure for approximately 4-16 weeks at temperatures ranging from approximately 25° C. to 95° C. Biomass may be lignocellulosic biomass and may be rendered suitable for enzymatic digestion or pulp production.Type: ApplicationFiled: September 5, 2007Publication date: May 29, 2008Applicant: The Texas A&M University SystemInventors: Mark Thomas Holtzapple, Richard Read Davison, Lee Leon Lowery, Cesar Benigno Granda
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Publication number: 20040168960Abstract: According to one embodiment of the invention, a system for processing biomass includes a water-impermeable bottom liner, a gravel layer supported by the bottom liner, a drain pipe disposed within the gravel layer, a biomass input device operable to deliver biomass over the gravel layer to form a biomass pile, a lime input device operable to deliver lime to the biomass for pretreating the biomass, a distribution pipe elevated above the gravel layer, and a pump operable to circulate water through the biomass pile by delivering water to the distribution pipe and receiving water from the drain pipe after it has traveled through the biomass pile.Type: ApplicationFiled: October 31, 2003Publication date: September 2, 2004Applicant: The Texas A&M University SystemInventors: Mark Thomas Holtzapple, Richard Read Davison, Lee Leon Lowery, Cesar Benigno Granda
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Publication number: 20040152881Abstract: A process for solubilization of protein including application of an alkali, such as lime, and heating. The process may also involve lime recovery and may be accomplished in a single stage or two stages to separate protein solubilized from labile and recalcitrant sources. Systems and devices for use in such process, including a continuous stirred tank reactor and a plug flow reactor are also involved.Type: ApplicationFiled: November 7, 2003Publication date: August 5, 2004Applicant: The Texas A&M University SystemInventors: Mark Thomas Holtzapple, Richard Davison, Guillermo Coward Kelly