Abstract: Systems and methods according to the present invention address these needs and others by providing a handheld device, e.g., a 3D pointing device, which uses at least one sensor to detect motion of the handheld device. The detected motion can then be mapped into a desired output, e.g., cursor movement.

Abstract: There is disclosed a drinking receptacle comprising: a container for containing a fluid for drinking; and an outlet member having an outlet through which the fluid is delivered under a pressure supplied by a user of the receptacle and a collar portion that attaches to an opening of the container such that an undersurface of the collar portion abuts with an upper surface of the opening of the container to form a substantially sealed engagement between the outlet member and the container; wherein either the undersurface of the collar portion or the upper surface of the opening of the container has at least one vent formed therein, the at least one vent being configured such that when said pressure is applied to the outlet member the at least one vent member permits the controlled ingress of air into the container to facilitate flow of fluid from the outlet, and when said pressure is removed the at least one vent member substantially prevents the ingress of air into the container to facilitate a controlled vacuu

Abstract: Systems and methods according to the present invention address these needs and others by providing a handheld device, e.g., a 3D pointing device, which uses at least one sensor to detect motion of the handheld device. The detected motion can then be mapped into a desired output, e.g., cursor movement.

Abstract: According to one aspect of the present disclosure, an induction-based reference point locator is provided. The locator includes transmitter locatable at a position on a first side of a structure, the transmitter configured to generate an alternating magnetic field at a desired frequency; and a receiver locatable on a second side of the structure opposite the first side, the receiver configured to detect the magnetic field and provide a directional indication to the position of the transmitter relative to the second side of the structure.

Abstract: The invention provides LNA therapeutics oligonucleotide carbohydrate conjugates with considerably enhanced potency, extended therapeutic index and reduced toxicity.

Abstract: Consistent with embodiments of the present disclosure, a Document Layering (DL) platform may enable a user to overlay a color layer and/or an interactive electronic layer on an existing legacy document. Such embodiments may begin by receiving a legacy document and a specification of layers to be added to the legacy document. The legacy document may include, for example, a PDF document. The specified layers may include, for example, color layer design or an interactive layer design. The DL platform may overlay the color design and/or interactive layer design upon the legacy document. Further, the DL platform may output an updated document comprised of the legacy document with the color layer and/or the interactive layer overlaid upon it.

Abstract: According to one aspect of the present disclosure, an induction-based reference point locator is provided. The locator includes transmitter locatable at a position on a first side of a structure, the transmitter configured to generate an alternating magnetic field at a desired frequency; and a receiver locatable on a second side of the structure opposite the first side, the receiver configured to detect the magnetic field and provide a directional indication to the position of the transmitter relative to the second side of the structure.

Abstract: The present invention relates to conjugates of LNA antisense oligonucleotides (oligomers) that target ApoB.

Abstract: Context awareness enables devices, e.g., smart televisions, to perform context-based actions without requiring user interaction. This enables users to more rapidly access desired content or applications via these devices without needing to navigate complicated user interfaces.

Abstract: A Targeted Content Marketing (TCM) platform may be provided. Consistent with embodiments of the present disclosure, TCM platform may enable the dynamic placement of, for example, targeted messages, advertisements and/or onserts (hereinafter referred to as “content”) in various documents. The content may be placed within any portion of the document, including, but not limited to for example, the body, margins, various fields, and any white-space in the document. In addition to being effective with high-volume electronic document processing, TCM platform may be integrated with, but not limited to, for example, outbound printing and communication channels, interactive voice response (IVR) systems, and customer service (CSR) popup message prompts.

Abstract: An auxiliary tank for a liquid is removably mounted on a rod extending from a support attached to selected threaded studs supporting a spare tire on a vehicle. A plurality of snaplock elements retain the tank locked with the support. A second tank for a liquid may be mounted on the rod adjacent the first tank. A further plurality of snaplock elements interlock the two tanks with one another. To prevent unauthorized removal of the tank(s), a conventional padlock is engaged with a passageway at the end of the rod. A variant support includes a flange for attachment to a bumper, running board, or the like, of a vehicle.

Abstract: A process of enzymatic degumming edible oils, comprising treating edible oil with a lipid acyltransferase so as to transfer an acyl group from a major part of the phospholipid to one or more acyl acceptors, wherein the acyl acceptor may be any compound comprising a hydroxyl group. In one embodiment preferably the acyl acceptor is water and in another embodiment preferably the acyl acceptor is one or more sterols and/or stanols. When the acyl acceptor is a stanol and/or sterol, one or more sterol esters and/or stanol esters are produced.

Abstract: The present disclosure relates to devices, systems, and methods for evaluating and preserving arteriovenous access sites. More particularly, the present disclosure relates to a sensor wire that is sized, shaped, and configured to pass through a delivery instrument to measure pressure and flow within and around an AV access site, thereby indicating the impact of the arteriovenous access site on the blood flow to the surrounding vasculature and tissues in real time. Also, the present disclosure relates to a therapeutic system comprising a combination pressure-flow sensor wire, a balloon catheter with imaging capabilities, and a computer system to allow the user to evaluate the blood flow and blood pressure within and around an AV access site in real time, diagnose the presence of complications associated with arteriovenous access sites, treat such complications, and assess the effectiveness of treatment both during and after treatment.

Abstract: Systems and methods according to the present invention address these needs and others by providing a handheld device, e.g., a 3D device, which uses at least one sensor to detect motion of the handheld device. The detected motion can then be mapped into a desired output, e.g., cursor movement.

Abstract: A method comprises generating a laser signal; scanning the laser signal into a field of view; and processing the return signal.

Abstract: Systems and methods for social networking, in which a user of a social networking system may interact with other users, comprises using a processor to associate a telephone number, such as a cell phone number, with the user and to use the telephone number as an identifier of the user in the social networking system. A prospective contact may be identified with the telephone number of the prospective contact. The user may integrate access to multiple social networking systems by selecting one or more of the multiple networking systems as desired networking systems for the user's interaction with a contact. A contact may choose which of the multiple systems to select for interacting with the user. Further, contacts may be grouped in the networking system, and the user may present customized user profiles to contacts based on the groupings.

Abstract: A line retrieval system comprises a retrieval device having a radially magnetized magnet adapted to be magnetically coupled to an object disposed on an opposite side of a structure for drawing the object in a desired direction relative to the structure.

Abstract: An auxiliary tank for a liquid is removably mounted on a rod extending from a support attached to selected threaded studs supporting a spare tire on a vehicle. A plurality of snaplock elements retain the tank locked with the support. A second tank for a liquid may be mounted on the rod adjacent the first tank. A further plurality of snaplock elements interlock the two tanks with one another. To prevent unauthorized removal of the tank(s), a conventional padlock is engaged with a passageway at the end of the rod. A variant support includes a flange for attachment to a bumper, running board, or the like, of a vehicle.

Abstract: A lighting fixture with a unique modular design is described. The said lighting fixture is comprised of a thermally conductive structure that provides the heat sinking and mounting surfaces for the light emitting diodes, the power supply(s), and the lens optics. The lens optics are designed in such a way as to accommodate a variety of warehouse aisle geometries or cavity ratios.