Patents by Inventor Mark W. Surber

Mark W. Surber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOGENIC MINICELLS AND METHODS OF USE
    Publication number: 20120252099
    Abstract: The disclosed invention relates to immunogenic minicells cells (anucleated) and their use to induce an immune response from a subject.
    Type: Application
    Filed: March 5, 2012
    Publication date: October 4, 2012
    Applicant: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber, Matthew J. Giacalone
  • MINICELL BASED DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS
    Publication number: 20120142079
    Abstract: Minicells are used to deliver biologically active compounds including radioisotopes, polypeptides, nucleic acids, small molecules, drug molecules, and chemotherapeutic agents. In some cases, the minicell displays ligands or binding moieties that target the minicell to a desired host cell.
    Type: Application
    Filed: November 11, 2011
    Publication date: June 7, 2012
    Applicant: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber, Robert Klepper
  • MINICELL BASED DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS
    Publication number: 20120135503
    Abstract: Minicells are used to deliver biologically active compounds including radioisotopes, polypeptides, nucleic acids, small molecules, drug molecules, and chemotherapeutic agents. In some cases, the minicell displays ligands or binding moieties that target the minicell to a desired host cell.
    Type: Application
    Filed: November 11, 2011
    Publication date: May 31, 2012
    Applicant: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber
  • Minicells displaying antibodies or derivatives thereof and comprising biologically active compounds
    Patent number: 8101396
    Abstract: Minicells are used to deliver biologically active compounds including radioisotopes, polypeptides, nucleic acids, small molecules, drug molecules, and chemotherapeutic agents. In some cases, the minicell displays ligands or binding moieties that target the minicell to a desired host cell.
    Type: Grant
    Filed: March 16, 2007
    Date of Patent: January 24, 2012
    Assignee: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber, Robert Klepper
  • MINICELLS EXPRESSING ANTIBODIES OR DERIVATIVES THEREOF AND COMPRISING BIOLOGICALLY ACTIVE COMPOUNDS
    Publication number: 20110281330
    Abstract: Minicells are used to deliver biologically active compounds including radioisotopes, polypeptides, nucleic acids, small molecules, drug molecules, and chemotherapeutic agents. In some cases, the minicell displays ligands or binding moieties that target the minicell to a desired host cell.
    Type: Application
    Filed: March 16, 2007
    Publication date: November 17, 2011
    Applicant: VAXIION THERAPEUTICS, INC.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber
  • Rhamnose-inducible expression constructs and methods
    Patent number: 7871815
    Abstract: Disclosed herein is a rhamnose-inducible expression vector.
    Type: Grant
    Filed: October 11, 2006
    Date of Patent: January 18, 2011
    Assignee: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber
  • Aerosolized fluoroquinolones and uses thereof
    Patent number: 7838532
    Abstract: Disclosed herein are formulations of fluoroquinolones suitable for aerosolization and use of such formulations for aerosol administration of fluoroquinolone antimicrobials for the treatment of pulmonary bacterial infections. In particular, inhaled levofloxacin specifically formulated and delivered for bacterial infections of the lungs is described. Methods include inhalation protocols and manufacturing procedures for production and use of the compositions described.
    Type: Grant
    Filed: May 18, 2006
    Date of Patent: November 23, 2010
    Assignee: Mpex Pharmaceuticals, Inc.
    Inventors: Mark W. Surber, Keith A. Bostian, Michael N. Dudley, Olga Lomovskaya, David C. Griffith
  • AEROSOLIZED FLUOROQUINOLONES AND USES THEREOF
    Publication number: 20100166673
    Abstract: Disclosed herein are formulations of fluoroquinolones suitable for aerosolization and use of such formulations for aerosol administration of fluoroquinolone antimicrobials for the treatment of pulmonary bacterial infections. In particular, inhaled levofloxacin specifically formulated and delivered for bacterial infections of the lungs is described. Methods include inhalation protocols and manufacturing procedures for production and use of the compositions described.
    Type: Application
    Filed: October 22, 2009
    Publication date: July 1, 2010
    Applicant: MPEX PHARMACEUTICALS, INC.
    Inventors: Mark W. Surber, Keith A. Bostian, Michael N. Dudley, Olga Lomovskaya, David C. Griffith
  • AEROSOLIZED FLUOROQUINOLONES AND USES THEREOF
    Publication number: 20100158957
    Abstract: Disclosed herein are formulations of fluoroquinolones suitable for aerosolization and use of such formulations for aerosol administration of fluoroquinolone antimicrobials for the treatment of pulmonary bacterial infections. In particular, inhaled levofloxacin specifically formulated and delivered for bacterial infections of the lungs is described. Methods include inhalation protocols and manufacturing procedures for production and use of the compositions described.
    Type: Application
    Filed: January 28, 2010
    Publication date: June 24, 2010
    Applicant: MPEX PHARMACEUTICALS, INC.
    Inventors: Mark W. Surber, Keith A. Bostian, Michael N. Dudley, Olga Rodny, David C. Griffith
  • AEROSOL FLUOROQUINOLONE FORMULATIONS FOR IMPROVED PHARMACOKINETICS
    Publication number: 20100087416
    Abstract: The present invention relates to the field of antimicrobial agents. In particular, the present invention relates to the use of aerosolized fluoroquinolones formulated with divalent or trivalent cations and having improved pulmonary availability for the treatment and management of bacterial infections of the lung and upper respiratory tract.
    Type: Application
    Filed: October 6, 2009
    Publication date: April 8, 2010
    Applicant: MPEX PHARMACEUTICALS, INC.
    Inventors: David C. Griffith, Michael N. Dudley, Mark W. Surber, Keith A. Bostian, Olga Rodny
  • AEROSOLIZED FLUOROQUINOLONES AND USES THEREOF
    Publication number: 20100037890
    Abstract: Disclosed herein are formulations of fluoroquinolones suitable for aerosolization and use of such formulations for aerosol administration of fluoroquinolone antimicrobials for the treatment of pulmonary bacterial infections. In particular, inhaled levofloxacin specifically formulated and delivered for bacterial infections of the lungs is described. Methods include inhalation protocols and manufacturing procedures for production and use of the compositions described.
    Type: Application
    Filed: October 22, 2009
    Publication date: February 18, 2010
    Applicant: MPEX PHARMACEUTICALS, INC.
    Inventors: Mark W. Surber, Keith A. Bostian, Michael N. Dudley, Olga Lomovskaya (AKA Olga Rodny), David C. Griffith
  • AEROSOLIZED FLUOROQUINOLONES AND USES THEREOF
    Publication number: 20100040560
    Abstract: Disclosed herein are formulations of fluoroquinolones suitable for aerosolization and use of such formulations for aerosol administration of fluoroquinolone antimicrobials for the treatment of pulmonary bacterial infections. In particular, inhaled levofloxacin specifically formulated and delivered for bacterial infections of the lungs is described. Methods include inhalation protocols and manufacturing procedures for production and use of the compositions described.
    Type: Application
    Filed: October 22, 2009
    Publication date: February 18, 2010
    Applicant: MPEX PHARMACEUTICALS, INC.
    Inventors: Mark W. Surber, Keith A. Bostian, Michael N. Dudley, Olga Lomovskaya, David C. Griffith
  • AEROSOLIZED NITRITE AND NITRIC OXIDE -DONATING COMPOUNDS AND USES THEREOF
    Publication number: 20090196930
    Abstract: Disclosed herein are formulations of nitrite, nitrite salt, or nitrite- or nitric oxide-producing compounds suitable for aerosolization and use of such formulations for aerosol administration of nitrite, nitrite salt, or nitrite- or nitric oxide-donating compounds for the treatment of pulmonary arterial hypertension, intra-nasal or pulmonary bacterial infections, or to treat or prevent ischemic reperfusion injury of the heart, brain and organs involved in transplantation. In particular, inhaled nitrite, nitrite salt, or nitrite- or nitric oxide-donating compound specifically formulated and delivered to the respiratory tract for the indications is described. Compositions include all formulations, kits, and device combinations described herein. Methods include inhalation procedures and manufacturing processes for production and use of the compositions described.
    Type: Application
    Filed: December 24, 2008
    Publication date: August 6, 2009
    Applicant: Aires Pharmaceuticals, Inc.
    Inventors: Mark W. Surber, Gary T. Elliott, Geoffrey Eugene Barker
  • MINICELLS AS VACCINES
    Publication number: 20090004744
    Abstract: The disclosed invention relates to immunogenic minicells cells (anucleated) and their use to induce an immune response from a subject.
    Type: Application
    Filed: April 30, 2008
    Publication date: January 1, 2009
    Applicant: Vaxiion Therapeutics, Inc.
    Inventors: Mark W. Surber, Roger Sabbadini, Neil Berkley
  • Eubacterial minicells and their use as vectors for nucleic acid delivery and expression
    Patent number: 7183105
    Abstract: Th invention provides compositions and methods for the production of achromosomal and anucleate cells useful for applications such as diagnositic and therapeutic uses, as well as research tools and agents for drug discovery.
    Type: Grant
    Filed: May 28, 2002
    Date of Patent: February 27, 2007
    Assignee: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber
  • Poroplasts
    Publication number: 20040005700
    Abstract: The invention provides compositions and methods for the production of achromosomal and anucleate cells useful for applications such as diagnostic and therapeutic uses, as well as research tools and agents for drug discovery.
    Type: Application
    Filed: May 28, 2002
    Publication date: January 8, 2004
    Inventors: Mark W. Surber, Matthew Giacalone
  • Minicell-based screening for compounds and proteins that modulate the activity of signalling proteins
    Publication number: 20030232335
    Abstract: The invention provides compositions and methods for the production of achromosomal and anucleate cells useful for applications such as diagnositic and therapeutic uses, as well as research tools and agents for drug discovery.
    Type: Application
    Filed: May 28, 2002
    Publication date: December 18, 2003
    Inventors: Mark W. Surber, Neil Berkley
  • Reverse screening and target identification with minicells
    Publication number: 20030224369
    Abstract: The invention provides compositions and methods for the production of achromosomal and anucleate cells useful for applications such as diagnositic and therapeutic uses, as well as research tools and agents for drug discovery.
    Type: Application
    Filed: May 28, 2002
    Publication date: December 4, 2003
    Inventors: Mark W. Surber, Neil Berkley, William Gerhart
  • Antibodies to native conformations of membrane proteins
    Publication number: 20030224444
    Abstract: The invention provides compositions and methods for the production of achromosomal and anucleate cells useful for applications such as diagnositic and therapeutic uses, as well as research tools and agents for drug discovery.
    Type: Application
    Filed: May 28, 2002
    Publication date: December 4, 2003
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber
  • Minicell-based delivery agents
    Publication number: 20030211599
    Abstract: The invention provides compositions and methods for the production of achromosomal and anucleate cells useful for applications such as diagnositic and therapeutic uses, as well as research tools and agents for drug discovery.
    Type: Application
    Filed: May 28, 2002
    Publication date: November 13, 2003
    Inventors: Roger A. Sabbadini, Robert Klepper, Mark W. Surber