Patents by Inventor Mark Westerman
Mark Westerman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11142572Abstract: Disclosed herein are antibodies specific for erythroferrone and assays comprising the antibodies. Also disclosed are methods for using the assays for the diagnosis or monitoring of disease.Type: GrantFiled: February 21, 2020Date of Patent: October 12, 2021Assignee: INTRINSIC LIFESCIENCES LLCInventors: Mark Westerman, Huiling Han, Vaughn Ostland
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Publication number: 20200300873Abstract: The present invention is generally related to kits for measuring a level of hepcidin in a biological sample in an in vitro assay compared to a standard control. The kits may further include instructions for use, a label for use, or both. The kits may be used to identify an individual having a disease or disorder associated with an elevated level of hepcidin, a reduced level of hepcidin, an elevated level of iron, a reduced level of iron, or a combination thereof.Type: ApplicationFiled: November 21, 2016Publication date: September 24, 2020Inventors: Mark Westerman, Patrick Gutschow, Vaughn Ostland
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Publication number: 20200231668Abstract: Disclosed herein are antibodies specific for erythroferrone and assays comprising the antibodies. Also disclosed are methods for using the assays for the diagnosis or monitoring of disease.Type: ApplicationFiled: February 21, 2020Publication date: July 23, 2020Inventors: Mark Westerman, Huiling Han, Vaughn Ostland
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Patent number: 10604567Abstract: Disclosed herein are antibodies specific for erythroferrone and assays comprising the antibodies. Also disclosed are methods for using the assays for the diagnosis or monitoring of disease.Type: GrantFiled: March 13, 2018Date of Patent: March 31, 2020Assignee: INTRINSIC LIFESCIENCES LLCInventors: Mark Westerman, Huiling Han, Vaughn Ostland
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Patent number: 10323088Abstract: The present application relates to humanized antibodies that specifically bind to hepcidin and methods of using the humanized antibodies. Another aspect relates to humanized antibodies which bind hepcidin and regulate iron homeostasis. Another aspect relates to the use of humanized antibodies which bind hepcidin for the treatment of a disease or condition associated with hepcidin.Type: GrantFiled: September 22, 2015Date of Patent: June 18, 2019Assignee: INTRINSIC LIFESCIENCES LLCInventor: Mark Westerman
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Patent number: 10239941Abstract: The present application relates to antibodies that specifically bind to hepcidin and methods of using the antibodies. Another aspect relates to antibodies which bind hepcidin and regulate iron homeostasis. Another aspect relates to the use of humanized antibodies which bind hepcidin for the treatment of a disease or condition associated with hepcidin.Type: GrantFiled: August 31, 2017Date of Patent: March 26, 2019Assignee: Intrinsic Lifesciences LLCInventors: Mark Westerman, Vaughn Ostland, Huiling Han, Patrick Gutschow, Keith Westerman, Gordana Olbina
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Publication number: 20180258168Abstract: Disclosed herein are antibodies specific for erythroferrone and assays comprising the antibodies. Also disclosed are methods for using the assays for the diagnosis or monitoring of disease.Type: ApplicationFiled: March 13, 2018Publication date: September 13, 2018Inventors: Mark Westerman, Huiling Han, Vaughn Ostland
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Publication number: 20180057586Abstract: The present application relates to antibodies that specifically bind to hepcidin and methods of using the antibodies. Another aspect relates to antibodies which bind hepcidin and regulate iron homeostasis. Another aspect relates to the use of humanized antibodies which bind hepcidin for the treatment of a disease or condition associated with hepcidin.Type: ApplicationFiled: August 31, 2017Publication date: March 1, 2018Inventors: Mark Westerman, Vaughn Ostland, Huiling Han, Patrick Gutschow, Keith Westerman, Gordana Olbina
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Patent number: 9803011Abstract: The present application relates to antibodies that specifically bind to hepcidin and methods of using the antibodies. Another aspect relates to antibodies which bind hepcidin and regulate iron homeostasis. Another aspect relates to the use of humanized antibodies which bind hepcidin for the treatment of a disease or condition associated with hepcidin.Type: GrantFiled: April 11, 2017Date of Patent: October 31, 2017Assignee: Intrinsic Lifesciences LLCInventors: Mark Westerman, Vaughn Ostland, Huiling Han, Patrick Gutschow, Keith Westerman, Gordana Olbina
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Publication number: 20170283495Abstract: The present application relates to antibodies that specifically bind to hepcidin and methods of using the antibodies. Another aspect relates to antibodies which bind hepcidin and regulate iron homeostasis. Another aspect relates to the use of humanized antibodies which bind hepcidin for the treatment of a disease or condition associated with hepcidin.Type: ApplicationFiled: April 11, 2017Publication date: October 5, 2017Inventors: Mark WESTERMAN, Vaughn OSTLAND, Huiling HAN, Patrick GUTSCHOW, Keith WESTERMAN, Gordana OLBINA
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Publication number: 20170247448Abstract: The present application relates to humanized antibodies that specifically bind to hepcidin and methods of using the humanized antibodies. Another aspect relates to humanized antibodies which bind hepcidin and regulate iron homeostasis. Another aspect relates to the use of humanized antibodies which bind hepcidin for the treatment of a disease or condition associated with hepcidin.Type: ApplicationFiled: September 22, 2015Publication date: August 31, 2017Applicant: Intrinsic Lifesciences LLCInventor: Mark WESTERMAN
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Patent number: 9731905Abstract: A stockpile control system adapted for use on a stockpile conveyor comprising a sensor that is disposed on the stockpile conveyor, a limit switch that is disposed on the stockpile conveyor, a pile probe that is disposed on the stockpile conveyor, and a microprocessor that is in operative communication with the limit switch and the sensor. The stockpile conveyor is adapted to move, the sensor is adapted to measure the location of the stockpile conveyor, the limit switch is adapted to limit the movement of the stockpile conveyor, the pile probe is adapted to measure a distance between the stockpile conveyor and a stockpile, and the microprocessor is adapted to control the movement of the stockpile conveyor. A method for controlling the production of a stockpile comprising providing a stockpile control system, calculating one or more stockpile boundaries, and controlling the movement of the stockpile conveyor.Type: GrantFiled: June 6, 2016Date of Patent: August 15, 2017Assignee: Kolberg-Pioneer, Inc.Inventors: Keith Enge, Mark Westerman
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Patent number: 9657098Abstract: The present application relates to antibodies that specifically bind to hepcidin and methods of using the antibodies. Another aspect relates to antibodies which bind hepcidin and regulate iron homeostasis. Another aspect relates to the use of humanized antibodies which bind hepcidin for the treatment of a disease or condition associated with hepcidin.Type: GrantFiled: March 13, 2014Date of Patent: May 23, 2017Assignee: INTRINSIC LIFESCIENCES, LLCInventors: Mark Westerman, Vaughn Ostland, Huiling Han, Patrick Gutschow, Keith Westerman, Gordana Olbina
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Publication number: 20160355351Abstract: A stockpile control system adapted for use on a stockpile conveyor comprising a sensor that is disposed on the stockpile conveyor, a limit switch that is disposed on the stockpile conveyor, a pile probe that is disposed on the stockpile conveyor, and a microprocessor that is in operative communication with the limit switch and the sensor. The stockpile conveyor is adapted to move, the sensor is adapted to measure the location of the stockpile conveyor, the limit switch is adapted to limit the movement of the stockpile conveyor, the pile probe is adapted to measure a distance between the stockpile conveyor and a stockpile, and the microprocessor is adapted to control the movement of the stockpile conveyor. A method for controlling the production of a stockpile comprising providing a stockpile control system, calculating one or more stockpile boundaries, and controlling the movement of the stockpile conveyor.Type: ApplicationFiled: June 6, 2016Publication date: December 8, 2016Applicant: Kolberg-Pioneer, Inc.Inventors: Keith Enge, Mark Westerman
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Publication number: 20160017032Abstract: The present application relates to antibodies that specifically bind to hepcidin and methods of using the antibodies. Another aspect relates to antibodies which bind hepcidin and regulate iron homeostasis. Another aspect relates to the use of humanized antibodies which bind hepcidin for the treatment of a disease or condition associated with hepcidin.Type: ApplicationFiled: March 13, 2014Publication date: January 21, 2016Inventors: Mark Westerman, Vaughn Ostland, Huiling Han, Patrick Gutschow, Keith Westerman, Gordana Olbina
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Patent number: 7464889Abstract: A method and apparatus for wirelessly monitoring and/or controlling the processing operations of a mobile rock crushing plant.Type: GrantFiled: November 27, 2006Date of Patent: December 16, 2008Assignee: Johnson Crushers InternationalInventors: Mark Westerman, James Donald Brock, Gary Heeszel, Lawrence Olsen, Robert Carnes
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Publication number: 20070158479Abstract: A method and apparatus for wirelessly monitoring and/or controlling the processing operations of a mobile rock crushing plant.Type: ApplicationFiled: November 27, 2006Publication date: July 12, 2007Applicant: Johnson Crushers InternationalInventors: Mark Westerman, James Brock, Gary Heeszel, Lawrence Olsen, Robert Carnes
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Publication number: 20060019339Abstract: The present invention concerns a method for the oxidative refolding of a hepcidin polypeptide to a form that is mature, bioactive and folded as in the native configuration and molecular mass; a method for measuring the level of native, bioactive hepcidin in a vertebrate animal; a method for measuring the level of hepcidin gene expression in a vertebrate animal; and a method for regulating the production of native, bioactive hepcidin in a vertebrate animal in vivo. The present invention also concerns an antibody or fragment thereof that specifically binds to a continuous, discontinuous, and/or conformational epitope of a mature and bioactive hepcidin folded as in the native configuration; and a pharmaceutical composition that includes the antibody or a hepcidin polypeptide and that provides antimicrobial, agonistic, or antagonistic activities in vivo in a vertebrate animal.Type: ApplicationFiled: April 28, 2005Publication date: January 26, 2006Inventors: Xavier Lauth, Mark Westerman, Vaughn Ostland, Jason Stannard, Michael Pennington