Patents by Inventor Markus Hornung

Markus Hornung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240050907
    Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
    Type: Application
    Filed: May 4, 2023
    Publication date: February 15, 2024
    Inventors: Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Bernd KRAUSE, Markus HORNUNG, Markus STORR, Heinrich BEHR, Werner BECK, Carina ZWEIGART, Reinhold BUCK, Philipp HERBST, Joachim LOERCHER, Arnd WOCHNER
  • Publication number: 20230271146
    Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
    Type: Application
    Filed: May 4, 2023
    Publication date: August 31, 2023
    Inventors: Markus HORNUNG, Bernd KRAUSE, Markus STORR, Philipp HERBST, Arnd WOCHNER, Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Carina ZWEIGART, Joachim LOERCHER, Reinhold BUCK, Heinrich BEHR, Werner BECK
  • Patent number: 11666868
    Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
    Type: Grant
    Filed: February 1, 2022
    Date of Patent: June 6, 2023
    Assignee: GAMBRO LUNDIA AB
    Inventors: Adriana Boschetti-De-Fierro, Manuel Voigt, Bernd Krause, Markus Hornung, Markus Storr, Heinrich Behr, Werner Beck, Carina Zweigart, Reinhold Buck, Philipp Herbst, Joachim Loercher, Arnd Wochner
  • Patent number: 11666869
    Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
    Type: Grant
    Filed: February 1, 2022
    Date of Patent: June 6, 2023
    Assignee: GAMBRO LUNDIA AB
    Inventors: Markus Hornung, Bernd Krause, Markus Storr, Philipp Herbst, Arnd Wochner, Adriana Boschetti-De-Fierro, Manuel Voigt, Carina Zweigart, Joachim Loercher, Reinhold Buck, Heinrich Behr, Werner Beck
  • Publication number: 20220339585
    Abstract: The present disclosure relates to a spinneret for producing hollow fiber membranes in a phase inversion process.
    Type: Application
    Filed: December 21, 2020
    Publication date: October 27, 2022
    Inventors: Reinhold BUCK, Evelyn GROSSMANN, Markus HORNUNG, Markus LOEFFLER, Heinrich BEHR, Arnd WOCHNER, Carl-Philipp SCHEUERMANN
  • Publication number: 20220152562
    Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
    Type: Application
    Filed: February 1, 2022
    Publication date: May 19, 2022
    Inventors: Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Bernd KRAUSE, Markus HORNUNG, Markus STORR, Heinrich BEHR, Werner BECK, Carina ZWEIGART, Reinhold BUCK, Philipp HERBST, Joachim LOERCHER, Arnd WOCHNER
  • Publication number: 20220152563
    Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
    Type: Application
    Filed: February 1, 2022
    Publication date: May 19, 2022
    Inventors: Markus HORNUNG, Bernd KRAUSE, Markus STORR, Philipp HERBST, Arnd WOCHNER, Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Carina ZWEIGART, Joachim LOERCHER, Reinhold BUCK, Heinrich BEHR, Werner BECK
  • Patent number: 11273416
    Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
    Type: Grant
    Filed: April 17, 2020
    Date of Patent: March 15, 2022
    Assignee: GAMBRO LUNDIA AB
    Inventors: Adriana Boschetti-De-Fierro, Manuel Voigt, Bernd Krause, Markus Hornung, Markus Storr, Heinrich Behr, Werner Beck, Carina Zweigart, Reinhold Buck, Philipp Herbst, Joachim Loercher, Arnd Wochner
  • Patent number: 11273417
    Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
    Type: Grant
    Filed: April 17, 2020
    Date of Patent: March 15, 2022
    Assignee: GAMBRO LUNDIA AB
    Inventors: Markus Hornung, Bernd Krause, Markus Storr, Philipp Herbst, Arnd Wochner, Adriana Boschetti-De-Fierro, Manuel Voigt, Carina Zweigart, Joachim Loercher, Reinhold Buck, Heinrich Behr, Werner Beck
  • Publication number: 20210229047
    Abstract: The present disclosure relates to synthetic membranes for the removal, isolation or purification of substances from a liquid, comprising at least one hydrophobic and at least one hydrophilic polymer, wherein 5-40 wt.-% of particles having an average particles size of between 0.1 and 15 ?m are entrapped and wherein the membrane has a wall thickness of below 150 ?m. Further disclosed are methods for preparing such membranes in various geometries and their use for the adsorption, isolation and/or purification of substances from a liquid.
    Type: Application
    Filed: March 31, 2021
    Publication date: July 29, 2021
    Inventors: Ralf FLIEG, Markus STORR, Bernd KRAUSE, Markus HORNUNG, Karl Heinz KLOTZ
  • Publication number: 20200316533
    Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
    Type: Application
    Filed: April 17, 2020
    Publication date: October 8, 2020
    Inventors: Markus HORNUNG, Bernd KRAUSE, Markus STORR, Philipp HERBST, Arnd WOCHNER, Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Carina ZWEIGART, Joachim LOERCHER, Reinhold BUCK, Heinrich BEHR, Werner BECK
  • Publication number: 20200269197
    Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
    Type: Application
    Filed: April 17, 2020
    Publication date: August 27, 2020
    Inventors: Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Bernd KRAUSE, Markus HORNUNG, Markus STORR, Heinrich BEHR, Werner BECK, Carina ZWEIGART, Reinhold BUCK, Philipp HERBST, Joachim LOERCHER, Arnd WOCHNER
  • Patent number: 10661231
    Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: May 26, 2020
    Assignee: GAMBRO LUNDIA AB
    Inventors: Adriana Boschetti-De-Fierro, Manuel Voigt, Bernd Krause, Markus Hornung, Markus Storr, Heinrich Behr, Werner Beck, Carina Zweigart, Reinhold Buck, Philipp Herbst, Joachim Loercher, Arnd Wochner
  • Patent number: 10661230
    Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: May 26, 2020
    Assignee: GAMBRO LUNDIA AB
    Inventors: Markus Hornung, Bernd Krause, Markus Storr, Philipp Herbst, Arnd Wochner, Adriana Boschetti-De-Fierro, Manuel Voigt, Carina Zweigart, Joachim Loercher, Reinhold Buck, Heinrich Behr, Werner Beck
  • Patent number: 10022481
    Abstract: The present disclosure relates to capillary dialyzers for blood purification comprising from 85-95% crimped fibers and from 5-15% non-crimped fibers.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: July 17, 2018
    Assignee: GAMBRO LUNDIA AB
    Inventors: Markus Hornung, Arnd Wochner, Reinhold Buck, Helmut Hildwein, Nikolaus Kanarjow
  • Patent number: 10005044
    Abstract: The invention relates to a virus filter membrane which can be used for the removal of virus particles including parvovirus. The invention further relates to a method for producing the membrane. The membrane comprises polyacrylonitrile and polyvinylpyrrolidone.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: June 26, 2018
    Assignee: GAMBRO LUNDIA AB
    Inventors: Markus Hornung, Bernd Krause, Johannes Geckeler, Ferdinand Schweiger, Szymon Dutczak, Simon Beiter
  • Patent number: 9776143
    Abstract: Porous hollow fiber membranes having a low molecular weight cut-off, processes for their production, and their use for separation tasks in the fields of biotechnology, pharmaceutical technology and food processing.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: October 3, 2017
    Assignee: GAMBRO LUNDIA AB
    Inventors: Bernd Krause, Markus Hornung, Johannes Geckeler
  • Publication number: 20170165615
    Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
    Type: Application
    Filed: February 5, 2015
    Publication date: June 15, 2017
    Inventors: Markus HORNUNG, Bernd KRAUSE, Markus STORR, Philipp HERBST, Arnd WOCHNER, Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Carina ZWEIGART, Joachim LOERCHER, Reinhold BUCK, Heinrich BEHR, Werner BECK
  • Publication number: 20170165616
    Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
    Type: Application
    Filed: February 5, 2015
    Publication date: June 15, 2017
    Inventors: Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Bernd KRAUSE, Markus HORNUNG, Markus STORR, Heinrich BEHR, Werner BECK, Carina ZWEIGART, Reinhold BUCK, Philipp HERBST, Joachim LOERCHER, Arnd WOCHNER
  • Publication number: 20160129172
    Abstract: The present disclosure relates to capillary dialyzers for blood purification comprising from 85-95% crimped fibres and from 5-15% non-crimped fibres.
    Type: Application
    Filed: June 19, 2014
    Publication date: May 12, 2016
    Inventors: Markus HORNUNG, Arnd WOCHNER, Reinhold BUCK, Helmut HILDWEIN, Nikolaus KANARJOW