Patents by Inventor Markus Hornung
Markus Hornung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240050907Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.Type: ApplicationFiled: May 4, 2023Publication date: February 15, 2024Inventors: Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Bernd KRAUSE, Markus HORNUNG, Markus STORR, Heinrich BEHR, Werner BECK, Carina ZWEIGART, Reinhold BUCK, Philipp HERBST, Joachim LOERCHER, Arnd WOCHNER
-
Publication number: 20230271146Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.Type: ApplicationFiled: May 4, 2023Publication date: August 31, 2023Inventors: Markus HORNUNG, Bernd KRAUSE, Markus STORR, Philipp HERBST, Arnd WOCHNER, Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Carina ZWEIGART, Joachim LOERCHER, Reinhold BUCK, Heinrich BEHR, Werner BECK
-
Patent number: 11666868Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.Type: GrantFiled: February 1, 2022Date of Patent: June 6, 2023Assignee: GAMBRO LUNDIA ABInventors: Adriana Boschetti-De-Fierro, Manuel Voigt, Bernd Krause, Markus Hornung, Markus Storr, Heinrich Behr, Werner Beck, Carina Zweigart, Reinhold Buck, Philipp Herbst, Joachim Loercher, Arnd Wochner
-
Patent number: 11666869Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.Type: GrantFiled: February 1, 2022Date of Patent: June 6, 2023Assignee: GAMBRO LUNDIA ABInventors: Markus Hornung, Bernd Krause, Markus Storr, Philipp Herbst, Arnd Wochner, Adriana Boschetti-De-Fierro, Manuel Voigt, Carina Zweigart, Joachim Loercher, Reinhold Buck, Heinrich Behr, Werner Beck
-
Publication number: 20220339585Abstract: The present disclosure relates to a spinneret for producing hollow fiber membranes in a phase inversion process.Type: ApplicationFiled: December 21, 2020Publication date: October 27, 2022Inventors: Reinhold BUCK, Evelyn GROSSMANN, Markus HORNUNG, Markus LOEFFLER, Heinrich BEHR, Arnd WOCHNER, Carl-Philipp SCHEUERMANN
-
Publication number: 20220152562Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.Type: ApplicationFiled: February 1, 2022Publication date: May 19, 2022Inventors: Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Bernd KRAUSE, Markus HORNUNG, Markus STORR, Heinrich BEHR, Werner BECK, Carina ZWEIGART, Reinhold BUCK, Philipp HERBST, Joachim LOERCHER, Arnd WOCHNER
-
Publication number: 20220152563Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.Type: ApplicationFiled: February 1, 2022Publication date: May 19, 2022Inventors: Markus HORNUNG, Bernd KRAUSE, Markus STORR, Philipp HERBST, Arnd WOCHNER, Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Carina ZWEIGART, Joachim LOERCHER, Reinhold BUCK, Heinrich BEHR, Werner BECK
-
Patent number: 11273416Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.Type: GrantFiled: April 17, 2020Date of Patent: March 15, 2022Assignee: GAMBRO LUNDIA ABInventors: Adriana Boschetti-De-Fierro, Manuel Voigt, Bernd Krause, Markus Hornung, Markus Storr, Heinrich Behr, Werner Beck, Carina Zweigart, Reinhold Buck, Philipp Herbst, Joachim Loercher, Arnd Wochner
-
Patent number: 11273417Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.Type: GrantFiled: April 17, 2020Date of Patent: March 15, 2022Assignee: GAMBRO LUNDIA ABInventors: Markus Hornung, Bernd Krause, Markus Storr, Philipp Herbst, Arnd Wochner, Adriana Boschetti-De-Fierro, Manuel Voigt, Carina Zweigart, Joachim Loercher, Reinhold Buck, Heinrich Behr, Werner Beck
-
Publication number: 20210229047Abstract: The present disclosure relates to synthetic membranes for the removal, isolation or purification of substances from a liquid, comprising at least one hydrophobic and at least one hydrophilic polymer, wherein 5-40 wt.-% of particles having an average particles size of between 0.1 and 15 ?m are entrapped and wherein the membrane has a wall thickness of below 150 ?m. Further disclosed are methods for preparing such membranes in various geometries and their use for the adsorption, isolation and/or purification of substances from a liquid.Type: ApplicationFiled: March 31, 2021Publication date: July 29, 2021Inventors: Ralf FLIEG, Markus STORR, Bernd KRAUSE, Markus HORNUNG, Karl Heinz KLOTZ
-
Publication number: 20200316533Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.Type: ApplicationFiled: April 17, 2020Publication date: October 8, 2020Inventors: Markus HORNUNG, Bernd KRAUSE, Markus STORR, Philipp HERBST, Arnd WOCHNER, Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Carina ZWEIGART, Joachim LOERCHER, Reinhold BUCK, Heinrich BEHR, Werner BECK
-
Publication number: 20200269197Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.Type: ApplicationFiled: April 17, 2020Publication date: August 27, 2020Inventors: Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Bernd KRAUSE, Markus HORNUNG, Markus STORR, Heinrich BEHR, Werner BECK, Carina ZWEIGART, Reinhold BUCK, Philipp HERBST, Joachim LOERCHER, Arnd WOCHNER
-
Patent number: 10661231Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.Type: GrantFiled: February 5, 2015Date of Patent: May 26, 2020Assignee: GAMBRO LUNDIA ABInventors: Adriana Boschetti-De-Fierro, Manuel Voigt, Bernd Krause, Markus Hornung, Markus Storr, Heinrich Behr, Werner Beck, Carina Zweigart, Reinhold Buck, Philipp Herbst, Joachim Loercher, Arnd Wochner
-
Patent number: 10661230Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.Type: GrantFiled: February 5, 2015Date of Patent: May 26, 2020Assignee: GAMBRO LUNDIA ABInventors: Markus Hornung, Bernd Krause, Markus Storr, Philipp Herbst, Arnd Wochner, Adriana Boschetti-De-Fierro, Manuel Voigt, Carina Zweigart, Joachim Loercher, Reinhold Buck, Heinrich Behr, Werner Beck
-
Patent number: 10022481Abstract: The present disclosure relates to capillary dialyzers for blood purification comprising from 85-95% crimped fibers and from 5-15% non-crimped fibers.Type: GrantFiled: June 19, 2014Date of Patent: July 17, 2018Assignee: GAMBRO LUNDIA ABInventors: Markus Hornung, Arnd Wochner, Reinhold Buck, Helmut Hildwein, Nikolaus Kanarjow
-
Patent number: 10005044Abstract: The invention relates to a virus filter membrane which can be used for the removal of virus particles including parvovirus. The invention further relates to a method for producing the membrane. The membrane comprises polyacrylonitrile and polyvinylpyrrolidone.Type: GrantFiled: February 24, 2014Date of Patent: June 26, 2018Assignee: GAMBRO LUNDIA ABInventors: Markus Hornung, Bernd Krause, Johannes Geckeler, Ferdinand Schweiger, Szymon Dutczak, Simon Beiter
-
Patent number: 9776143Abstract: Porous hollow fiber membranes having a low molecular weight cut-off, processes for their production, and their use for separation tasks in the fields of biotechnology, pharmaceutical technology and food processing.Type: GrantFiled: March 4, 2013Date of Patent: October 3, 2017Assignee: GAMBRO LUNDIA ABInventors: Bernd Krause, Markus Hornung, Johannes Geckeler
-
Publication number: 20170165615Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.Type: ApplicationFiled: February 5, 2015Publication date: June 15, 2017Inventors: Markus HORNUNG, Bernd KRAUSE, Markus STORR, Philipp HERBST, Arnd WOCHNER, Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Carina ZWEIGART, Joachim LOERCHER, Reinhold BUCK, Heinrich BEHR, Werner BECK
-
Publication number: 20170165616Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.Type: ApplicationFiled: February 5, 2015Publication date: June 15, 2017Inventors: Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Bernd KRAUSE, Markus HORNUNG, Markus STORR, Heinrich BEHR, Werner BECK, Carina ZWEIGART, Reinhold BUCK, Philipp HERBST, Joachim LOERCHER, Arnd WOCHNER
-
Publication number: 20160129172Abstract: The present disclosure relates to capillary dialyzers for blood purification comprising from 85-95% crimped fibres and from 5-15% non-crimped fibres.Type: ApplicationFiled: June 19, 2014Publication date: May 12, 2016Inventors: Markus HORNUNG, Arnd WOCHNER, Reinhold BUCK, Helmut HILDWEIN, Nikolaus KANARJOW